5WSG
 
 | | Cryo-EM structure of the Catalytic Step II spliceosome (C* complex) at 4.0 angstrom resolution | | Descriptor: | 3'-exon-intron, 3'-intron-lariat, 5'-exon, ... | | Authors: | Yan, C, Wan, R, Bai, R, Huang, G, Shi, Y. | | Deposit date: | 2016-12-07 | | Release date: | 2017-01-25 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structure of a yeast step II catalytically activated spliceosome
Science, 355, 2017
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5LJ3
 | | Structure of the core of the yeast spliceosome immediately after branching | | Descriptor: | CEF1, CLF1, CWC15, ... | | Authors: | Galej, W.P, Wilkinson, M.F, Fica, S.M, Oubridge, C, Newman, A.J, Nagai, K. | | Deposit date: | 2016-07-17 | | Release date: | 2016-08-03 | | Last modified: | 2019-10-23 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Cryo-EM structure of the spliceosome immediately after branching.
Nature, 537, 2016
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4Z11
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4Z12
 | | Recombinantly expressed latent aurone synthase (polyphenol oxidase) co-crystallized with hexatungstotellurate(VI) | | Descriptor: | 6-tungstotellurate(VI), Aurone synthase, COPPER (II) ION, ... | | Authors: | Molitor, C, Mauracher, S.G, Rompel, A. | | Deposit date: | 2015-03-26 | | Release date: | 2016-03-23 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Aurone synthase is a catechol oxidase with hydroxylase activity and provides insights into the mechanism of plant polyphenol oxidases.
Proc.Natl.Acad.Sci.USA, 113, 2016
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4Z13
 | | Recombinantly expressed latent aurone synthase (polyphenol oxidase) co-crystallized with hexatungstotellurate(VI) and soaked in H2O2 | | Descriptor: | 6-tungstotellurate(VI), Aurone synthase, COPPER (II) ION, ... | | Authors: | Molitor, C, Mauracher, S.G, Rompel, A. | | Deposit date: | 2015-03-26 | | Release date: | 2016-03-23 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Aurone synthase is a catechol oxidase with hydroxylase activity and provides insights into the mechanism of plant polyphenol oxidases.
Proc.Natl.Acad.Sci.USA, 113, 2016
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4Z14
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6HQJ
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6HQI
 | | holo-form of polyphenol oxidase from Solanum lycopersicum | | Descriptor: | COPPER (II) ION, OXYGEN ATOM, Polyphenol oxidase A, ... | | Authors: | Kampatsikas, I, Bijelic, A, Rompel, A. | | Deposit date: | 2018-09-25 | | Release date: | 2019-03-20 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Biochemical and structural characterization of tomato polyphenol oxidases provide novel insights into their substrate specificity.
Sci Rep, 9, 2019
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7QTT
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8H6K
 | | Cryo-EM structure of human exon-defined spliceosome in the mature B state. | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | | Deposit date: | 2022-10-18 | | Release date: | 2024-05-01 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
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7R5K
 | | Human nuclear pore complex (constricted) | | Descriptor: | Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... | | Authors: | Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. | | Deposit date: | 2022-02-10 | | Release date: | 2022-06-22 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (12 Å) | | Cite: | AI-based structure prediction empowers integrative structural analysis of human nuclear pores.
Science, 376, 2022
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7R5J
 | | Human nuclear pore complex (dilated) | | Descriptor: | Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... | | Authors: | Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. | | Deposit date: | 2022-02-10 | | Release date: | 2022-09-21 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (50 Å) | | Cite: | AI-based structure prediction empowers integrative structural analysis of human nuclear pores
Science, 376, 2022
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5ZWO
 | | Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom | | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ... | | Authors: | Bai, R, Wan, R, Yan, C, Shi, Y. | | Deposit date: | 2018-05-16 | | Release date: | 2018-08-29 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Science, 360, 2018
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5ZWM
 | | Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom (tri-snRNP and U2 snRNP Part) | | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, ... | | Authors: | Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y. | | Deposit date: | 2018-05-16 | | Release date: | 2018-08-29 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Science, 360, 2018
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6AH0
 | | The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Zhan, X, Yan, C, Zhang, X, Shi, Y. | | Deposit date: | 2018-08-15 | | Release date: | 2018-11-14 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (5.7 Å) | | Cite: | Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018
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6ELS
 | | Structure of latent apple tyrosinase (MdPPO1) | | Descriptor: | COPPER (II) ION, OXYGEN ATOM, Polyphenol oxidase, ... | | Authors: | Kampatsikas, I, Bijelic, A, Pretzler, M, Rompel, A. | | Deposit date: | 2017-09-29 | | Release date: | 2019-03-20 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.346 Å) | | Cite: | A Peptide-Induced Self-Cleavage Reaction Initiates the Activation of Tyrosinase.
Angew.Chem.Int.Ed.Engl., 58, 2019
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6FF7
 | | human Bact spliceosome core structure | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... | | Authors: | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | | Deposit date: | 2018-01-03 | | Release date: | 2019-03-13 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
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7ABF
 | | Human pre-Bact-1 spliceosome core structure | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | Deposit date: | 2020-09-07 | | Release date: | 2020-12-09 | | Last modified: | 2020-12-30 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
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7AAV
 | | Human pre-Bact-2 spliceosome core structure | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, D-chiro inositol hexakisphosphate, ... | | Authors: | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | Deposit date: | 2020-09-04 | | Release date: | 2020-12-09 | | Last modified: | 2020-12-30 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
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2Y7C
 | | Atomic model of the Ocr-bound methylase complex from the Type I restriction-modification enzyme EcoKI (M2S1). Based on fitting into EM map 1534. | | Descriptor: | GENE 0.3 PROTEIN, TYPE I RESTRICTION ENZYME ECOKI M PROTEIN, TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN | | Authors: | Kennaway, C.K, Obarska-Kosinska, A, White, J.H, Tuszynska, I, Cooper, L.P, Bujnicki, J.M, Trinick, J, Dryden, D.T.F. | | Deposit date: | 2011-01-31 | | Release date: | 2011-02-09 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (18 Å) | | Cite: | The Structure of M.Ecoki Type I DNA Methyltransferase with a DNA Mimic Antirestriction Protein.
Nucleic Acids Res., 37, 2009
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4TVR
 | | Tandem Tudor and PHD domains of UHRF2 | | Descriptor: | E3 ubiquitin-protein ligase UHRF2, UNKNOWN ATOM OR ION, ZINC ION | | Authors: | Walker, J.R, Dong, A, Zhang, Q, Ong, M, Duan, S, Li, Y, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | | Deposit date: | 2014-06-27 | | Release date: | 2015-06-24 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Structure of the Tandem Tudor and PHD domains of UHRF2
To be published
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8B74
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2Y7H
 | | Atomic model of the DNA-bound methylase complex from the Type I restriction-modification enzyme EcoKI (M2S1). Based on fitting into EM map 1534. | | Descriptor: | 5'-D(*GP*TP*TP*CP*AP*AP*CP*GP*TP*CP*GP*AP*CP*GP *TP*GP*CP*AP*AP*C)-3', 5'-D(*GP*TP*TP*GP*CP*AP*CP*GP*TP*CP*GP*AP*CP*GP *TP*TP*GP*AP*AP*C)-3', S-ADENOSYLMETHIONINE, ... | | Authors: | Kennaway, C.K, Obarska-Kosinska, A, White, J.H, Tuszynska, I, Cooper, L.P, Bujnicki, J.M, Trinick, J, Dryden, D.T.F. | | Deposit date: | 2011-01-31 | | Release date: | 2011-02-09 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (18 Å) | | Cite: | The Structure of M.Ecoki Type I DNA Methyltransferase with a DNA Mimic Antirestriction Protein.
Nucleic Acids Res., 37, 2009
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5A9Q
 | | Human nuclear pore complex | | Descriptor: | NUCLEAR PORE COMPLEX PROTEIN NUP107, NUCLEAR PORE COMPLEX PROTEIN NUP133, NUCLEAR PORE COMPLEX PROTEIN NUP155, ... | | Authors: | von Appen, A, Kosinski, J, Sparks, L, Ori, A, DiGuilio, A, Vollmer, B, Mackmull, M, Banterle, N, Parca, L, Kastritis, P, Buczak, K, Mosalaganti, S, Hagen, W, Andres-Pons, A, Lemke, E.A, Bork, P, Antonin, W, Glavy, J.S, Bui, K.H, Beck, M. | | Deposit date: | 2015-07-22 | | Release date: | 2015-09-30 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (23 Å) | | Cite: | In Situ Structural Analysis of the Human Nuclear Pore Complex
Nature, 526, 2015
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4V8S
 | | Archaeal RNAP-DNA binary complex at 4.32Ang | | Descriptor: | 5'-D(*AP*TP*AP*GP*AP*GP*TP*AP*TP*AP*AP*GP*AP*TP *AP*G)-3', 5'-D(*TP*CP*TP*TP*AP*TP*AP*CP*TP*CP*TP*AP*TP*CP)-3', DNA-DIRECTED RNA POLYMERASE, ... | | Authors: | Wojtas, M.N, Mogni, M, Millet, O, Bell, S.D, Abrescia, N.G.A. | | Deposit date: | 2012-07-12 | | Release date: | 2014-07-09 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (4.323 Å) | | Cite: | Structural and Functional Analyses of the Interaction of Archaeal RNA Polymerase with DNA.
Nucleic Acids Res., 40, 2012
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