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6T1G	Streptavidin variants harbouring an artificial organocatalyst based cofactor Descriptor: 1,2-ETHANEDIOL, 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(1-pyridin-4-ylpiperidin-4-yl)pentanamide, Streptavidin Authors: Lechner, H, Hocker, B. Deposit date: 2019-10-04 Release date: 2020-10-14 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: An Artificial Cofactor Catalyzing the Baylis-Hillman Reaction with Designed Streptavidin as Protein Host*. Chembiochem, 22, 2021
6SOK	Engineered streptavidin variant (VTAR) in complex with the Twin-Strep-tag peptide Descriptor: AMINO GROUP, Streptavidin, Twin-Strep-tag peptide Authors: Skerra, A, Eichinger, A. Deposit date: 2019-08-29 Release date: 2020-09-09 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.96 Å) Cite: The Role of Changing Loop Conformations in Streptavidin Versions Engineered for High-affinity Binding of the Strep-tag II Peptide. J.Mol.Biol., 433, 2021
1HQQ	MINIPROTEIN MP-2 (M9A) COMPLEX WITH STREPTAVIDIN Descriptor: MP-2, STREPTAVIDIN Authors: Yang, H.W, Liu, D.Q, Fan, X, White, M.A, Fox, R.O. Deposit date: 2000-12-19 Release date: 2003-09-16 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Conformational Ensemble Analysis of Ligand Binding in Streptavidin Mini-protein Complexes To be Published
6T2L	Streptavidin variants harbouring an artificial organocatalyst based cofactor Descriptor: 1,2-ETHANEDIOL, 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(1-pyridin-4-ylpiperidin-4-yl)pentanamide, GLYCEROL, ... Authors: Lechner, H, Hocker, B. Deposit date: 2019-10-09 Release date: 2020-10-14 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1 Å) Cite: An Artificial Cofactor Catalyzing the Baylis-Hillman Reaction with Designed Streptavidin as Protein Host*. Chembiochem, 22, 2021
6T30	Streptavidin variants harbouring an artificial organocatalyst based cofactor Descriptor: 1,2-ETHANEDIOL, 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(1-pyridin-4-ylpiperidin-4-yl)pentanamide, GLYCEROL, ... Authors: Lechner, H, Hocker, B. Deposit date: 2019-10-10 Release date: 2020-11-18 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.8 Å) Cite: An Artificial Cofactor Catalyzing the Baylis-Hillman Reaction with Designed Streptavidin as Protein Host*. Chembiochem, 22, 2021
1KL3	an engineered streptavidin with improved affinity for the strep-tag II peptide : SAm1-StrepII Descriptor: strep-tag II peptide, streptavidin Authors: Korndoerfer, I.P, Skerra, A. Deposit date: 2001-12-11 Release date: 2002-04-03 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site. Protein Sci., 11, 2002
1KFF	An engineered streptavidin with improved affinity for the strep-tag II peptide: apo-SAM1 Descriptor: streptavidin Authors: Korndoerfer, I.P, Skerra, A. Deposit date: 2001-11-20 Release date: 2002-04-03 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site. Protein Sci., 11, 2002
6SOS	Engineered streptavidin variant (ENAGY) in complex with the Twin-Strep-tag peptide Descriptor: Streptavidin, Twin-Strep-tag peptide Authors: Skerra, A, Eichinger, A. Deposit date: 2019-08-29 Release date: 2020-09-09 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The Role of Changing Loop Conformations in Streptavidin Versions Engineered for High-affinity Binding of the Strep-tag II Peptide. J.Mol.Biol., 433, 2021
6T1E	Streptavidin variants harbouring an artificial organocatalyst based cofactor Descriptor: 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(1-pyridin-4-ylpiperidin-4-yl)pentanamide, ACETATE ION, CHLORIDE ION, ... Authors: Lechner, H, Hocker, B. Deposit date: 2019-10-04 Release date: 2020-10-14 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.3 Å) Cite: An Artificial Cofactor Catalyzing the Baylis-Hillman Reaction with Designed Streptavidin as Protein Host*. Chembiochem, 22, 2021
1KL5	an engineered streptavidin with improved affinity for the strep-tag II peptide : SAm2-StrepII Descriptor: strep-tag II, streptavidin Authors: Korndoerfer, I.P, Skerra, A. Deposit date: 2001-12-11 Release date: 2002-04-03 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site. Protein Sci., 11, 2002
6T31	Streptavidin variants harbouring an artificial organocatalyst based cofactor Descriptor: 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(1-pyridin-4-ylpiperidin-4-yl)pentanamide, Streptavidin Authors: Lechner, H, Hocker, B. Deposit date: 2019-10-10 Release date: 2020-11-18 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.35 Å) Cite: An Artificial Cofactor Catalyzing the Baylis-Hillman Reaction with Designed Streptavidin as Protein Host*. Chembiochem, 22, 2021
6TIP	Engineered streptavidin variant (YNAFM) in complex with the Strep-tag II peptide Descriptor: AMINO GROUP, Strep-tag II peptide, Streptavidin Authors: Skerra, A, Eichinger, A. Deposit date: 2019-11-22 Release date: 2020-12-02 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The Role of Changing Loop Conformations in Streptavidin Versions Engineered for High-affinity Binding of the Strep-tag II Peptide. J.Mol.Biol., 433, 2021
1IJ8	CRYSTAL STRUCTURE OF LITE AVIDIN-BNI COMPLEX Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, AVIDIN Authors: Livnah, O, Huberman, T. Deposit date: 2001-04-25 Release date: 2001-09-12 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2 Å) Cite: Chicken avidin exhibits pseudo-catalytic properties. Biochemical, structural, and electrostatic consequences. J.Biol.Chem., 276, 2001
1LDO	avidin-norbioitn complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NORBIOTIN, avidin Authors: Pazy, Y, Kulik, T, Bayer, E.A, Wilchek, M, Livnah, O. Deposit date: 2002-04-09 Release date: 2002-11-06 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Ligand exchange between proteins: exchange of biotin and biotin derivatives between avidin and streptavidin J.Biol.Chem., 277, 2002
6S4Q	scdSav(SASK) - Engineering Single-Chain Dimeric Streptavidin as Host for Artificial Metalloenzymes Descriptor: GLYCEROL, Streptavidin, {N-(4-{[2-(amino-kappaN)ethyl]sulfamoyl-kappaN}phenyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}(chloro)[(1,2,3,4,5-eta)-1,2,3,4,5-pentamethylcyclopentadienyl]iridium(III) Authors: Rebelein, J.G. Deposit date: 2019-06-28 Release date: 2019-09-25 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Breaking Symmetry: Engineering Single-Chain Dimeric Streptavidin as Host for Artificial Metalloenzymes. J.Am.Chem.Soc., 141, 2019
6UD6	Spectroscopic and structural characterization of a genetically encoded direct sensor for protein-ligand interactions Descriptor: CHLORIDE ION, GLYCEROL, Streptavidin Authors: Mills, J.H, Gleason, P.R, Simmons, C.R, Henderson, J.N, Kartchner, B.K. Deposit date: 2019-09-18 Release date: 2020-09-23 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.502 Å) Cite: Structural Origins of Altered Spectroscopic Properties upon Ligand Binding in Proteins Containing a Fluorescent Noncanonical Amino Acid. Biochemistry, 60, 2021
6UDC	Spectroscopic and structural characterization of a genetically encoded direct sensor for protein-ligand interactions Descriptor: BIOTIN, Streptavidin Authors: Mills, J.H, Gleason, P.R, Simmons, C.R, Henderson, J.N, Kartchner, B.K. Deposit date: 2019-09-19 Release date: 2020-09-23 Last modified: 2021-10-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural Origins of Altered Spectroscopic Properties upon Ligand Binding in Proteins Containing a Fluorescent Noncanonical Amino Acid. Biochemistry, 60, 2021
1KL4	AN ENGINEERED STREPTAVIDIN WITH IMPROVED AFFINITY FOR THE STREP-TAG II PEPTIDE : apo-SAM2 Descriptor: streptavidin Authors: Korndoerfer, I.P, Skerra, A. Deposit date: 2001-12-11 Release date: 2002-04-03 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site. Protein Sci., 11, 2002
1LCW	streptavidin-homobiotin complex Descriptor: HOMOBIOTIN, Streptavidin Authors: Livnah, O, Pazy, Y, Bayer, E.A, Wilchek, M. Deposit date: 2002-04-07 Release date: 2002-11-06 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Ligand exchange between proteins: exchange of biotin and biotin derivatives between avidin and streptavidin J.Biol.Chem., 277, 2002
1LEL	The avidin BCAP complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin, E-AMINO BIOTINYL CAPROIC ACID Authors: Pazy, Y, Kulik, T, Bayer, E.A, Wilchek, M, Livnah, O. Deposit date: 2002-04-10 Release date: 2002-11-06 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Ligand exchange between proteins: exchange of biotin and biotin derivatives between avidin and streptavidin J.Biol.Chem., 277, 2002
1LCZ	streptavidin-BCAP complex Descriptor: E-AMINO BIOTINYL CAPROIC ACID, Streptavidin Authors: Livnah, O, Pazy, Y, Bayer, E.A, Wilchek, M. Deposit date: 2002-04-08 Release date: 2002-11-06 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Ligand exchange between proteins: exchange of biotin and biotin derivatives between avidin and streptavidin J.Biol.Chem., 277, 2002
1LDQ	avidin-homobiotin complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin, HOMOBIOTIN Authors: Pazy, Y, Kulik, T, Bayer, E.A, Wilchek, M, Livnah, O. Deposit date: 2002-04-09 Release date: 2002-11-06 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Ligand exchange between proteins: exchange of biotin and biotin derivatives between avidin and streptavidin J.Biol.Chem., 277, 2002
1LCV	streptavidin-norbiotin complex Descriptor: NORBIOTIN, streptavidin Authors: Livnah, O, Pazy, Y. Deposit date: 2002-04-07 Release date: 2002-11-06 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Ligand exchange between proteins: exchange of biotin and biotin derivatives between avidin and streptavidin J.Biol.Chem., 277, 2002
1LUQ	Full Matrix Error Analysis of Streptavidin Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, BIOTIN, GLYCEROL, ... Authors: Merritt, E.A, Le Trong, I. Deposit date: 2002-05-23 Release date: 2003-09-09 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (0.96 Å) Cite: Full Matrix Error Analysis of Streptavidin To be Published
1VWA	STREPTAVIDIN-FSHPQNT Descriptor: PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN Authors: Katz, B.A, Cass, R.T. Deposit date: 1997-03-03 Release date: 1998-03-18 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.85 Å) Cite: In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0. J.Biol.Chem., 272, 1997

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