6UDC

Spectroscopic and structural characterization of a genetically encoded direct sensor for protein-ligand interactions

Summary for 6UDC

Entry DOI	10.2210/pdb6udc/pdb
Descriptor	Streptavidin, BIOTIN (3 entities in total)
Functional Keywords	unnatural amino acid, non-canonical amino acid, fluorescence, biosensor, small molecule biosensor, ligand detection, fluorescent protein
Biological source	Streptomyces avidinii
Total number of polymer chains	4
Total formula weight	59440.27
Authors	Mills, J.H.,Gleason, P.R.,Simmons, C.R.,Henderson, J.N.,Kartchner, B.K. (deposition date: 2019-09-19, release date: 2020-09-23, Last modification date: 2021-10-13)
Primary citation	Gleason, P.R.,Kolbaba-Kartchner, B.,Henderson, J.N.,Stahl, E.P.,Simmons, C.R.,Mills, J.H. Structural Origins of Altered Spectroscopic Properties upon Ligand Binding in Proteins Containing a Fluorescent Noncanonical Amino Acid. Biochemistry, 60:2577-2585, 2021 Cited by PubMed: 34415744 DOI: 10.1021/acs.biochem.1c00291 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation