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2OI3
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NMR Structure Analysis of the Hematopoetic Cell Kinase SH3 Domain complexed with an artificial high affinity ligand (PD1)
Descriptor: Tyrosine-protein kinase HCK, artificial peptide PD1
Authors:Schmidt, H, Stoldt, M, Hoffmann, S, Tran, T, Willbold, D.
Deposit date:2007-01-10
Release date:2007-02-20
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of a Hck SH3 Domain Ligand Complex Reveals Novel Interaction Modes
J.Mol.Biol., 365, 2007
2O9V
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The second SH3 domain from Ponsin in complex with the paxillin proline rich region
Descriptor: Paxillin, Ponsin
Authors:Pinotsis, N, Wilmanns, M.
Deposit date:2006-12-14
Release date:2007-10-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Paxillin and ponsin interact in nascent costameres of muscle cells
J.Mol.Biol., 369, 2007
2O88
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Crystal structure of the N114A mutant of ABL-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions
Descriptor: P41 peptide, Proto-oncogene tyrosine-protein kinase ABL1, SULFATE ION
Authors:Camara-Artigas, A.
Deposit date:2006-12-12
Release date:2007-05-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystallization by capillary counter-diffusion and structure determination of the N114A mutant of the SH3 domain of Abl tyrosine kinase complexed with a high-affinity peptide ligand.
Acta Crystallogr.,Sect.D, 63, 2007
2OAW
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Structure of SHH variant of "Bergerac" chimera of spectrin SH3
Descriptor: CHLORIDE ION, Spectrin alpha chain, brain
Authors:Gabdoulkhakov, A.G, Gushchina, L.V, Nikulin, A.D, Nikonov, S.V, Viguera, A.R, Serrano, L, Filimonov, V.V.
Deposit date:2006-12-18
Release date:2008-04-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and thermodynamic studies of Bergerac-SH3 chimeras.
Biophys.Chem., 139, 2009
2L2P
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Folding Intermediate of the Fyn SH3 A39V/N53P/V55L from NMR Relaxation Dispersion Experiments
Descriptor: Tyrosine-protein kinase Fyn
Authors:Neudecker, P, Robustelli, P, Cavalli, A, Vendruscolo, M, Kay, L.E.
Deposit date:2010-08-25
Release date:2011-09-14
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of an intermediate state in protein folding and aggregation.
Science, 336, 2012
2LP5
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Native Structure of the Fyn SH3 A39V/N53P/V55L
Descriptor: Tyrosine-protein kinase Fyn
Authors:Neudecker, P, Robustelli, P, Cavalli, A, Vendruscolo, M, Kay, L.E.
Deposit date:2012-02-06
Release date:2012-05-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of an intermediate state in protein folding and aggregation.
Science, 336, 2012
1SRL
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BU of 1srl by Molmil
1H AND 15N ASSIGNMENTS AND SECONDARY STRUCTURE OF THE SRC SH3 DOMAIN
Descriptor: SRC TYROSINE KINASE SH3 DOMAIN
Authors:Yu, H, Rosen, M.K, Shin, T.B, Seidel-Dugan, C, Brugge, J.S, Schreiber, S.L.
Deposit date:1994-03-07
Release date:1994-05-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:1H and 15N assignments and secondary structure of the Src SH3 domain.
FEBS Lett., 324, 1993
1TG0
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0.97-A structure of the SH3 domain of bbc1
Descriptor: Myosin tail region-interacting protein MTI1
Authors:Kursula, P, Kursula, I, Lehmann, F, Song, Y.H, Wilmanns, M.
Deposit date:2004-05-28
Release date:2005-06-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Saccharomyces cerevisiae SH3 domain structural genomics
To be Published
1SSH
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Crystal structure of the SH3 domain from a S. cerevisiae hypothetical 40.4 kDa protein in complex with a peptide
Descriptor: 12-mer peptide from Cytoskeleton assembly control protein SLA1, Hypothetical 40.4 kDa protein in PES4-HIS2 intergenic region
Authors:Kursula, P, Kursula, I, Lehmann, F, Song, Y.-H, Wilmanns, M.
Deposit date:2004-03-24
Release date:2005-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Yeast SH3 domain structural genomics
To be Published
1SEM
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BU of 1sem by Molmil
STRUCTURAL DETERMINANTS OF PEPTIDE-BINDING ORIENTATION AND OF SEQUENCE SPECIFICITY IN SH3 DOMAINS
Descriptor: 10-RESIDUE PROLINE-RICH PEPTIDE FROM MSOS (ACE-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG), SEM-5
Authors:Lim, W.A, Richards, F.M, Fox, R.O.
Deposit date:1995-03-28
Release date:1995-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains.
Nature, 372, 1994
1SHG
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CRYSTAL STRUCTURE OF A SRC-HOMOLOGY 3 (SH3) DOMAIN
Descriptor: ALPHA-SPECTRIN SH3 DOMAIN
Authors:Noble, M, Pauptit, R, Musacchio, A, Saraste, M, Wierenga, R.K.
Deposit date:1993-05-19
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a Src-homology 3 (SH3) domain.
Nature, 359, 1992
1QWF
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C-SRC SH3 DOMAIN COMPLEXED WITH LIGAND VSL12
Descriptor: TYROSINE-PROTEIN KINASE TRANSFORMING PROTEIN SRC, VAL-SER-LEU-ALA-ARG-ARG-PRO-LEU-PRO-PRO-LEU-PRO
Authors:Feng, S, Chiyoshi, K, Rickles, R.J, Schreiber, S.L.
Deposit date:1995-11-09
Release date:1996-03-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands.
Proc.Natl.Acad.Sci.USA, 92, 1995
1QWE
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BU of 1qwe by Molmil
C-SRC SH3 DOMAIN COMPLEXED WITH LIGAND APP12
Descriptor: ALA-PRO-PRO-LEU-PRO-PRO-ARG-ASN-ARG-PRO-ARG-LEU, TYROSINE-PROTEIN KINASE TRANSFORMING PROTEIN SRC
Authors:Feng, S, Chiyoshi, K, Rickles, R.J, Schreiber, S.L.
Deposit date:1995-11-09
Release date:1996-03-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands.
Proc.Natl.Acad.Sci.USA, 92, 1995
1TUD
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BU of 1tud by Molmil
ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT N47-D48
Descriptor: ALPHA-SPECTRIN
Authors:Viguera, A.R, Serrano, L, Wilmanns, M.
Deposit date:1996-02-29
Release date:1996-08-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics.
J.Mol.Biol., 247, 1995
1RLP
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TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS
Descriptor: C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND RLP2 (RALPPLPRY)
Authors:Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L.
Deposit date:1994-10-10
Release date:1995-02-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions.
Science, 266, 1994
1S1N
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BU of 1s1n by Molmil
SH3 domain of human nephrocystin
Descriptor: Nephrocystin 1
Authors:Le Maire, A, Weber, T, Saunier, S, Antignac, C, Ducruix, A, Dardel, F.
Deposit date:2004-01-07
Release date:2005-01-18
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution NMR structure of the SH3 domain of human nephrocystin and analysis of a mutation-causing juvenile nephronophthisis.
Proteins, 59, 2005
1U3O
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BU of 1u3o by Molmil
Solution structure of rat Kalirin N-terminal SH3 domain
Descriptor: Huntingtin-associated protein-interacting protein
Authors:Schiller, M.R, Chakrabarti, K, King, G.F, Schiller, N.I, Eipper, B.A, Maciejewski, M.W.
Deposit date:2004-07-22
Release date:2005-07-26
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Regulation of RhoGEF Activity by Intramolecular and Intermolecular SH3 Domain Interactions.
J.Biol.Chem., 281, 2006
1UE9
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BU of 1ue9 by Molmil
Solution structure of the fourth SH3 domain of human intersectin 2 (KIAA1256)
Descriptor: Intersectin 2
Authors:Tochio, N, Kigawa, T, Koshiba, S, Kobayashi, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-05-09
Release date:2003-11-09
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the fourth SH3 domain of human intersectin 2 (KIAA1256)
To be Published
1RLQ
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TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS
Descriptor: C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND RLP2 (RALPPLPRY)
Authors:Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L.
Deposit date:1994-10-10
Release date:1995-02-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions.
Science, 266, 1994
1RUW
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BU of 1ruw by Molmil
Crystal structure of the SH3 domain from S. cerevisiae Myo3
Descriptor: IMIDAZOLE, Myosin-3 isoform
Authors:Kursula, P, Kursula, I, Lehmann, F, Song, Y.H, Wilmanns, M.
Deposit date:2003-12-12
Release date:2005-03-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the SH3 domain from S. cerevisiae Myo3
To be Published
1TUC
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ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT S19-P20
Descriptor: ALPHA-SPECTRIN
Authors:Wilmanns, M, Serrano, L, Viguera, A.R.
Deposit date:1996-02-29
Release date:1996-08-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics.
J.Mol.Biol., 247, 1995
1UHF
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Solution Structure of the third SH3 domain of human intersectin 2(KIAA1256)
Descriptor: INTERSECTIN 2
Authors:Suzuki, S, Hatanaka, H, Koshiba, S, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-07-03
Release date:2004-08-10
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of the third SH3 domain of human intersectin 2(KIAA1256)
To be Published
1UJ0
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Crystal Structure of STAM2 SH3 domain in complex with a UBPY-derived peptide
Descriptor: PHOSPHATE ION, deubiquitinating enzyme UBPY, signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
Authors:Kaneko, T, Kumasaka, T, Ganbe, T, Sato, T, Miyazawa, K, Kitamura, N, Tanaka, N.
Deposit date:2003-07-24
Release date:2003-12-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domain.
J.Biol.Chem., 278, 2003
1U06
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crystal structure of chicken alpha-spectrin SH3 domain
Descriptor: AZIDE ION, Spectrin alpha chain, brain
Authors:Chevelkov, V, Faelber, K, Diehl, A, Heinemann, U, Oschkinat, H, Reif, B.
Deposit date:2004-07-13
Release date:2005-01-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Detection of dynamic water molecules in a microcrystalline sample of the SH3 domain of alpha-spectrin by MAS solid-state NMR.
J.Biomol.Nmr, 31, 2005
1VA7
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Yeast Myo3 SH3 domain, triclinic crystal form
Descriptor: GLYCEROL, Myosin-3 isoform
Authors:Kursula, P, Lehmann, F, Song, Y.H, Wilmanns, M.
Deposit date:2004-02-12
Release date:2005-06-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:High-throughput structural genomics of yeast SH3 domains
To be Published

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