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8FI7
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BU of 8fi7 by Molmil
Structure of Lettuce C20T bound to DFHO
Descriptor: (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, Lettuce DNA aptamer, MAGNESIUM ION, ...
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2022-12-15
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Intricate 3D architecture of a DNA mimic of GFP.
Nature, 618, 2023
8FHX
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BU of 8fhx by Molmil
Structure of Lettuce aptamer bound to DFHBI-1T
Descriptor: (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, Lettuce DNA aptamer, MAGNESIUM ION, ...
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2022-12-15
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Intricate 3D architecture of a DNA mimic of GFP.
Nature, 618, 2023
4DXI
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BU of 4dxi by Molmil
Crystal Structure of an Ancestor of All Faviina Proteins
Descriptor: GREEN FLUORESCENT PROTEIN, MAGNESIUM ION
Authors:Kim, H, Wachter, R.M.
Deposit date:2012-02-27
Release date:2013-02-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A hinge migration mechanism unlocks the evolution of green-to-red photoconversion in GFP-like proteins.
Structure, 23, 2015
3ST3
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BU of 3st3 by Molmil
Dreiklang - off state
Descriptor: Dreiklang, PHOSPHATE ION
Authors:Brakemann, T, Weber, G, Andresen, M, Stiel, A.C, Jakobs, S, Wahl, M.C.
Deposit date:2011-07-08
Release date:2011-09-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching.
Nat.Biotechnol., 29, 2011
7LG4
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BU of 7lg4 by Molmil
Green fluorescent protein from Aequorea macrodactyla - amacGFP
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Bozhanova, N.G, Meiler, J.
Deposit date:2021-01-19
Release date:2021-01-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Heterogeneity of the GFP fitness landscape and data-driven protein design.
Elife, 11, 2022
5O8A
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BU of 5o8a by Molmil
Crystal Structure of rsEGFP2 in the non-fluorescent off-state determined by SFX
Descriptor: Green fluorescent protein
Authors:Coquelle, N, Sliwa, M, Woodhouse, J, Schiro, G, Adam, V, Aquila, A, Barends, T.R.M, Boutet, S, Byrdin, M, Carbajo, S, De la Mora, E, Doak, R.B, Feliks, M, Fieschi, F, Foucar, L, Guillon, V, Hilpert, M, Hunter, M, Jakobs, S, Koglin, J.E, Kovacsova, G, Lane, T.J, Levy, B, Liang, M, Nass, K, Ridard, J, Robinson, J.S, Roome, C.M, Ruckebusch, C, Seaberg, M, Thepaut, M, Cammarata, M, Demachy, I, Field, M, Shoeman, R.L, Bourgeois, D, Colletier, J.P, Schlichting, I, Weik, M.
Deposit date:2017-06-12
Release date:2017-09-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography.
Nat Chem, 10, 2018
4KZE
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BU of 4kze by Molmil
Crystal structure of an RNA aptamer in complex with Fab
Descriptor: BL3-6 Fab antibody, heavy chain, light chain, ...
Authors:Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A.
Deposit date:2013-05-29
Release date:2014-06-18
Last modified:2014-07-30
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
4KZD
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BU of 4kzd by Molmil
Crystal structure of an RNA aptamer in complex with fluorophore and Fab
Descriptor: 4-(3,5-difluoro-4-hydroxybenzyl)-1,2-dimethyl-1H-imidazol-5-ol, BL3-6 Fab antibody, heavy chain, ...
Authors:Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A.
Deposit date:2013-05-29
Release date:2014-06-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.186 Å)
Cite:A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
8A83
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BU of 8a83 by Molmil
rsEGFP2 with a chlorinated chromophore in the fluorescent ON-state in a crystal dehydrated after illumination
Descriptor: Green fluorescent protein, SULFATE ION
Authors:Fadini, A, van Thor, J, Chang, J.
Deposit date:2022-06-21
Release date:2023-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Serial Femtosecond Crystallography Reveals that Photoactivation in a Fluorescent Protein Proceeds via the Hula Twist Mechanism.
J.Am.Chem.Soc., 145, 2023
3U8P
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BU of 3u8p by Molmil
Cytochrome b562 integral fusion with EGFP
Descriptor: Cytochrome b562 integral fusion with enhanced green fluorescent protein, PROTOPORPHYRIN IX CONTAINING FE
Authors:Arpino, J, Czapinska, H, Piasecka, A, Edwards, W.R, Barker, P, Gajda, M, Bochtler, M, Jones, D.D.
Deposit date:2011-10-17
Release date:2012-08-29
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for efficient chromophore communication and energy transfer in a constructed didomain protein scaffold.
J.Am.Chem.Soc., 134, 2012
6ZQO
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BU of 6zqo by Molmil
EYFP mutant - F165G
Descriptor: G protein/GFP fusion protein, SULFATE ION
Authors:Pletnev, V.Z, Pletnev, S.V, Pletneva, N.V.
Deposit date:2020-07-10
Release date:2021-06-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Amino acid residue at the 165th position tunes EYFP chromophore maturation. A structure-based design.
Comput Struct Biotechnol J, 19, 2021
6ZWC
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BU of 6zwc by Molmil
Z-SBTub2 photoswitch bound to tubulin-DARPin D1 complex
Descriptor: 2-[2-(3,4,5-trimethoxyphenyl)ethyl]-1,3-benzothiazole, Designed Ankyrin Repeat Protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Wranik, M, Weinert, T, Olieric, N, Gao, L, Kraus, Y.C.M, Bingham, R, Ntouliou, E, Ahlfeld, J, Thorn-Seshold, O, Steinmetz, M.O, Standfuss, J.
Deposit date:2020-07-28
Release date:2020-12-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:A Robust, GFP-Orthogonal Photoswitchable Inhibitor Scaffold Extends Optical Control over the Microtubule Cytoskeleton.
Cell Chem Biol, 28, 2021
6ZWB
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BU of 6zwb by Molmil
Z-SBTub3 photoswitch bound to tubulin-DARPin D1 complex
Descriptor: 5-[2-(1,3-benzothiazol-2-yl)ethyl]-2-methoxy-phenol, Designed Ankyrin Repeat Protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Wranik, M, Weinert, T, Olieric, N, Gao, L, Kraus, Y.C.M, Bingham, R, Ntouliou, E, Ahlfeld, J, Thorn-Seshold, O, Steinmetz, M.O, Standfuss, J.
Deposit date:2020-07-28
Release date:2020-12-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.747 Å)
Cite:A Robust, GFP-Orthogonal Photoswitchable Inhibitor Scaffold Extends Optical Control over the Microtubule Cytoskeleton.
Cell Chem Biol, 28, 2021
8U21
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BU of 8u21 by Molmil
A Highly Stable Variant of Corynactis Californica Green Fluorescent Protein, ccGFP E6
Descriptor: Green Fluorescent Protein Variant E6, ccGFP E6
Authors:Hung, L.-W, Terwilliger, T.C, Waldo, G, Nguyen, H.B.
Deposit date:2023-09-05
Release date:2024-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Engineering highly stable variants of Corynactis californica green fluorescent proteins.
Protein Sci., 33, 2024
8U23
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BU of 8u23 by Molmil
A Highly Stable Variant of Corynactis Californica Green Fluorescent Protein, ccGFP 8
Descriptor: Green Fluorescent Protein Variant #8, ccGFP 8
Authors:Hung, L.-W, Terwilliger, T.C, Waldo, G, Nguyen, H.B.
Deposit date:2023-09-05
Release date:2024-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Engineering highly stable variants of Corynactis californica green fluorescent proteins.
Protein Sci., 33, 2024
8U22
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BU of 8u22 by Molmil
A Highly Stable Variant of Corynactis Californica Green Fluorescent Protein, ccGFP 7
Descriptor: Green Fluorescent Protein Variant #7, ccGFP 7
Authors:Hung, L.-W, Terwilliger, T.C, Waldo, G, Nguyen, H.B.
Deposit date:2023-09-05
Release date:2024-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Engineering highly stable variants of Corynactis californica green fluorescent proteins.
Protein Sci., 33, 2024
8U24
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BU of 8u24 by Molmil
A Highly Stable Variant of Corynactis Californica Green Fluorescent Protein, ccGFP 9
Descriptor: Green Fluorescent Protein Variant #9, ccGFP 9
Authors:Hung, L.-W, Terwilliger, T.C, Waldo, G, Nguyen, H.B.
Deposit date:2023-09-05
Release date:2024-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Engineering highly stable variants of Corynactis californica green fluorescent proteins.
Protein Sci., 33, 2024
8U20
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BU of 8u20 by Molmil
A Highly Stable Variant of Corynactis Californica Green Fluorescent Protein, ccGFP 5
Descriptor: Green Fluorescent Protein Variant #5, ccGFP 5
Authors:Hung, L.-W, Terwilliger, T.C, Waldo, G, Nguyen, H.B.
Deposit date:2023-09-05
Release date:2024-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Engineering highly stable variants of Corynactis californica green fluorescent proteins.
Protein Sci., 33, 2024
5YR2
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BU of 5yr2 by Molmil
Structure of cpGFP66BPA
Descriptor: Green fluorescent protein
Authors:Wang, L, Kang, F, Wang, J.
Deposit date:2017-11-08
Release date:2019-01-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Structure of cpGFP66BPA
To Be Published
5Y8R
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BU of 5y8r by Molmil
ZsYellow at pH 3.5
Descriptor: GFP-like fluorescent chromoprotein FP538
Authors:Bae, J.E, Kim, I.J, Nam, K.H.
Deposit date:2017-08-21
Release date:2017-09-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Disruption of the hydrogen bonding network determines the pH-induced non-fluorescent state of the fluorescent protein ZsYellow by protonation of Glu221.
Biochem. Biophys. Res. Commun., 493, 2017
5Y8Q
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BU of 5y8q by Molmil
ZsYellow at pH 8.0
Descriptor: GFP-like fluorescent chromoprotein FP538
Authors:Bae, J.E, Kim, I.J, Nam, K.H.
Deposit date:2017-08-21
Release date:2017-09-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Disruption of the hydrogen bonding network determines the pH-induced non-fluorescent state of the fluorescent protein ZsYellow by protonation of Glu221.
Biochem. Biophys. Res. Commun., 493, 2017
2OTB
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BU of 2otb by Molmil
Crystal structure of a monomeric cyan fluorescent protein in the fluorescent state
Descriptor: GFP-like fluorescent chromoprotein cFP484
Authors:Henderson, J.N, Ai, H, Campbell, R.E, Remington, S.J.
Deposit date:2007-02-07
Release date:2007-04-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural basis for reversible photobleaching of a green fluorescent protein homologue.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4Q9W
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BU of 4q9w by Molmil
mTFP*: a robust and versatile host protein at 1.00 A resolution
Descriptor: GFP-like fluorescent chromoprotein cFP484
Authors:Fischer, J, Quitterer, F, Groll, M, Eppinger, J.
Deposit date:2014-05-02
Release date:2014-05-21
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1 Å)
Cite:mTFP*: An imperishable and versatile protein host for anchoring diverse ligands and organocatalysts
To be Published
6LOF
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BU of 6lof by Molmil
Crystal structure of ZsYellow soaked by Cu2+
Descriptor: GFP-like fluorescent chromoprotein FP538
Authors:Nam, K.H.
Deposit date:2020-01-05
Release date:2020-01-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Spectroscopic and Structural Analysis of Cu 2+ -Induced Fluorescence Quenching of ZsYellow.
Biosensors (Basel), 10, 2020
7A7L
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BU of 7a7l by Molmil
rsEGFP in the green-off state
Descriptor: Green fluorescent protein, TETRAETHYLENE GLYCOL
Authors:De Zitter, E, Dedecker, P, Van Meervelt, L.
Deposit date:2020-08-30
Release date:2021-02-17
Last modified:2021-05-05
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure-Function Dataset Reveals Environment Effects within a Fluorescent Protein Model System*.
Angew.Chem.Int.Ed.Engl., 60, 2021

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