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8WQE
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BU of 8wqe by Molmil
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 1)
Descriptor: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
Authors:Chen, X, Zhang, K, Xu, C.
Deposit date:2023-10-11
Release date:2024-04-03
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
9B5F
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BU of 9b5f by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 1 map and model (Ub(A)/ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5I
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BU of 9b5i by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 4 map and model (Ub(A)-AMP/PPi/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
8XTG
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BU of 8xtg by Molmil
Crystal structure of methyltransferase MpaG' in complex with SAH and DMMPA
Descriptor: O-desmethyl mycophenolic acid, O-methyltransferase mpaG', S-ADENOSYL-L-HOMOCYSTEINE
Authors:You, C, Pan, Y.J, Li, S.Y, Feng, Y.G.
Deposit date:2024-01-10
Release date:2024-08-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for substrate flexibility of the O-methyltransferase MpaG' involved in mycophenolic acid biosynthesis.
Protein Sci., 33, 2024
9B5L
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BU of 9b5l by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - Ub(T) class 10 map and model from cluster 5 (Ub(A)-AMP)
Descriptor: 4-aminobutanenitrile, ADENOSINE MONOPHOSPHATE, Polyubiquitin, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
8XTE
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BU of 8xte by Molmil
Crystal structure of methyltransferase MpaG' in complex with SAH and FDHMP
Descriptor: 4-farnesyl-3,5-dihydroxy-6-methylphthalide, O-methyltransferase mpaG', S-ADENOSYL-L-HOMOCYSTEINE
Authors:You, C, Pan, Y.J, Li, S.Y, Feng, Y.G.
Deposit date:2024-01-10
Release date:2024-08-28
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural basis for substrate flexibility of the O-methyltransferase MpaG' involved in mycophenolic acid biosynthesis.
Protein Sci., 33, 2024
9B5Q
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BU of 9b5q by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - cluster 2 map and model (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
8VHW
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BU of 8vhw by Molmil
Neutron Structure of Peroxide-Soaked Trp161Phe MnSOD
Descriptor: HYDROGEN PEROXIDE, MANGANESE (II) ION, Superoxide dismutase [Mn], ...
Authors:Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Coates, L, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O.
Deposit date:2024-01-02
Release date:2024-07-31
Last modified:2024-10-16
Method:NEUTRON DIFFRACTION (2.3 Å)
Cite:Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
Nat Commun, 15, 2024
8VJ5
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BU of 8vj5 by Molmil
Peroxide-Soaked MnSOD
Descriptor: HYDROGEN PEROXIDE, MANGANESE (II) ION, PHOSPHATE ION, ...
Authors:Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O.
Deposit date:2024-01-05
Release date:2024-07-31
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
Nat Commun, 15, 2024
2UXC
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BU of 2uxc by Molmil
Crystal structure of an extended tRNA anticodon stem loop in complex with its cognate mRNA UCGU in the context of the Thermus thermophilus 30S subunit.
Descriptor: 16S RIBOSOMAL RNA, A-SITE MESSENGER RNA FRAGMENT CGGG, ANTICODON STEM-LOOP OF TRANSFER RNA WITH ANTICODON ACGA, ...
Authors:Dunham, C.M, Selmer, M, Phelps, S.S, Kelley, A.C, Suzuki, T, Joseph, S, Ramakrishnan, V.
Deposit date:2007-03-28
Release date:2007-05-08
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of Trnas with an Expanded Anticodon Loop in the Decoding Center of the 30S Ribosomal Subunit.
RNA, 13, 2007
9B5H
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BU of 9b5h by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 3 map and model (Ub(A)-AMP/PPi/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE MONOPHOSPHATE, Large ribosomal subunit protein eL40B, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5S
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BU of 9b5s by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - cluster 4 map and model (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5X
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BU of 9b5x by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 10 map and model from cluster 5 (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
8XB8
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BU of 8xb8 by Molmil
The structure of ASFV A137R
Descriptor: A137R
Authors:Li, C, Song, H, Gao, G.F.
Deposit date:2023-12-06
Release date:2024-01-31
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:African swine fever virus A137R assembles into a dodecahedron cage.
J.Virol., 98, 2024
8WQC
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BU of 8wqc by Molmil
cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CDK5R1
Descriptor: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
Authors:Chen, X, Zhang, K, Xu, C.
Deposit date:2023-10-11
Release date:2024-04-03
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8VHY
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BU of 8vhy by Molmil
Neutron Structure of Reduced Trp161Phe MnSOD
Descriptor: MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial
Authors:Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Coates, L, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O.
Deposit date:2024-01-02
Release date:2024-07-31
Last modified:2024-10-16
Method:NEUTRON DIFFRACTION (2.3 Å)
Cite:Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
Nat Commun, 15, 2024
8WQD
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BU of 8wqd by Molmil
Local refinement of FEM1B bound with the C-degron of CCC89
Descriptor: Coiled-coil domain-containing protein 89, Protein fem-1 homolog B
Authors:Chen, X, Zhang, K, Xu, C.
Deposit date:2023-10-11
Release date:2024-04-03
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
9B5M
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BU of 9b5m by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - consensus map and model
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5V
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BU of 9b5v by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 10 map and model from cluster 1 (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (3.94 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
8YI7
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BU of 8yi7 by Molmil
The Cryo-EM structure of IL-12, receptor subunit beta-1 and receptor subunit beta-2 complex, local refinement
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1, Interleukin-12 receptor subunit beta-2, ...
Authors:Chen, H.Q, Ge, X.F.
Deposit date:2024-02-29
Release date:2024-07-24
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Structure and assembly of the human IL-12 signaling complex.
Structure, 2024
8XM7
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BU of 8xm7 by Molmil
Cryo-EM structure of the RhoG/DOCK5/ELMO1/Rac1 complex: RhoG/DOCK5/ELMO1 focused map
Descriptor: Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Kukimoto-Niino, M, Katsura, K, Ishizuka-Katsura, Y, Mishima-Tsumagari, C, Yonemochi, M, Inoue, M, Nakagawa, R, Kaushik, R, Zhang, K.Y.J, Shirouzu, M.
Deposit date:2023-12-27
Release date:2024-06-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (4.91 Å)
Cite:RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state.
J.Biol.Chem., 300, 2024
9ASH
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BU of 9ash by Molmil
Cryo-EM structure of the active Lactococcus lactis Csm bound to target in post-cleavage stage
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CRISPR RNA, CRISPR system Cms endoribonuclease Csm3, ...
Authors:Wang, B, Goswami, H.N, Li, H.
Deposit date:2024-02-25
Release date:2024-08-14
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Molecular basis for cA6 synthesis by a type III-A CRISPR-Cas enzyme and its conversion to cA4 production.
Nucleic Acids Res., 52, 2024
8XT3
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BU of 8xt3 by Molmil
Cryo-EM structure of the human 39S mitoribosome with 10uM Tigecycline
Descriptor: 16s rRNA, 39S ribosomal protein L22, mitochondrial, ...
Authors:Li, X, Wang, M, Cheng, J.
Deposit date:2024-01-10
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8Z3S
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BU of 8z3s by Molmil
Activation mechanism and novel binding site of the BKCa channel activator CTIBD
Descriptor: 4-[4-(4-chlorophenyl)-3-(trifluoromethyl)-1,2-oxazol-5-yl]benzene-1,3-diol, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ...
Authors:Lee, N, Kim, S, Jo, H, Lee, N.Y, Jin, M.S, Park, C.S.
Deposit date:2024-04-16
Release date:2024-07-31
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Activation mechanism and novel binding sites of the BK Ca channel activator CTIBD.
Life Sci Alliance, 7, 2024
8YA8
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BU of 8ya8 by Molmil
The crystal structure of human Rtel1 HHD2 domain
Descriptor: Regulator of telomere elongation helicase 1
Authors:Chun, I.S, Kim, M.S.
Deposit date:2024-02-08
Release date:2024-02-28
Last modified:2024-09-11
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structure of the HHD2 domain in human RTEL1
Biodesign, 12, 2024

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PDB entries from 2024-10-16

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