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7NH5
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BU of 7nh5 by Molmil
Co-Crystal Structure of Akt1 in Complex with Covalent-Allosteric Akt Inhibitor 6
Descriptor: ACETATE ION, RAC-alpha serine/threonine-protein kinase, ~{N}-methyl-6-[4-[[4-[2-oxidanylidene-6-(propanoylamino)-3~{H}-benzimidazol-1-yl]piperidin-1-yl]methyl]phenyl]-5-phenyl-pyridine-3-carboxamide
Authors:Landel, I, Mueller, M.P, Rauh, D.
Deposit date:2021-02-10
Release date:2021-09-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cellular model system to dissect the isoform-selectivity of Akt inhibitors.
Nat Commun, 12, 2021
7PXH
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BU of 7pxh by Molmil
Emodepside-bound Drosophila Slo channel
Descriptor: (3~{S},6~{R},9~{S},12~{R},15~{S},18~{R},21~{S},24~{R})-4,6,10,16,18,22-hexamethyl-3,9,15,21-tetrakis(2-methylpropyl)-12,24-bis[(4-morpholin-4-ylphenyl)methyl]-1,7,13,19-tetraoxa-4,10,16,22-tetrazacyclotetracosane-2,5,8,11,14,17,20,23-octone, (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, ...
Authors:Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S.
Deposit date:2021-10-08
Release date:2021-12-15
Last modified:2021-12-22
Method:ELECTRON MICROSCOPY (2.59 Å)
Cite:Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM.
Nat Commun, 12, 2021
7PXE
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BU of 7pxe by Molmil
Ca2+ bound Drosophila Slo channel
Descriptor: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ...
Authors:Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S.
Deposit date:2021-10-08
Release date:2021-12-15
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.38 Å)
Cite:Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM.
Nat Commun, 12, 2021
7NA0
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BU of 7na0 by Molmil
Structure of Geobacter sulfurreducens proline utilization A (PutA) variant A206W
Descriptor: 1,2-ETHANEDIOL, Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Korasick, D.A.
Deposit date:2021-06-19
Release date:2021-09-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the function of a ligand-modulated dynamic tunnel in bifunctional proline utilization A (PutA).
Arch.Biochem.Biophys., 712, 2021
7PK9
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BU of 7pk9 by Molmil
C-reactive protein decamer at pH 7.5
Descriptor: C-reactive protein, CALCIUM ION
Authors:Noone, D.P, Sharp, T.H.
Deposit date:2021-08-25
Release date:2021-12-22
Last modified:2022-01-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-Electron Microscopy and Biochemical Analysis Offer Insights Into the Effects of Acidic pH, Such as Occur During Acidosis, on the Complement Binding Properties of C-Reactive Protein.
Front Immunol, 12, 2021
7PTR
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BU of 7ptr by Molmil
Structure of hexameric S-layer protein from Haloferax volcanii archaea
Descriptor: CALCIUM ION, Cell surface glycoprotein, beta-D-glucopyranose
Authors:von Kuegelgen, A, Bharat, T.A.M.
Deposit date:2021-09-27
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Complete atomic structure of a native archaeal cell surface.
Cell Rep, 37, 2021
7N32
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BU of 7n32 by Molmil
protofilaments of microtubule doublets bound to outer-arm dynein
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Rao, Q, Zhang, K.
Deposit date:2021-05-31
Release date:2021-09-29
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.
Nat.Struct.Mol.Biol., 28, 2021
7NA6
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BU of 7na6 by Molmil
Cryo-EM structure of AAV True Type
Descriptor: Capsid protein VP1
Authors:Bennett, A.D, McKenna, R.
Deposit date:2021-06-19
Release date:2021-09-29
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2.
J.Struct.Biol., 213, 2021
1WL9
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BU of 1wl9 by Molmil
Structure of aminopeptidase P from E. coli
Descriptor: CHLORIDE ION, MANGANESE (II) ION, Xaa-Pro aminopeptidase
Authors:Graham, S.C, Bond, C.S, Freeman, H.C, Guss, J.M.
Deposit date:2004-06-22
Release date:2005-08-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional implications of metal ion selection in aminopeptidase p, a metalloprotease with a dinuclear metal center
Biochemistry, 44, 2005
7PKF
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BU of 7pkf by Molmil
C-reactive protein decamer at pH 5
Descriptor: C-reactive protein, CALCIUM ION
Authors:Noone, D.P, Sharp, T.H.
Deposit date:2021-08-25
Release date:2021-12-22
Last modified:2022-01-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-Electron Microscopy and Biochemical Analysis Offer Insights Into the Effects of Acidic pH, Such as Occur During Acidosis, on the Complement Binding Properties of C-Reactive Protein.
Front Immunol, 12, 2021
7Q0G
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BU of 7q0g by Molmil
Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-49 and FI-3A Fabs
Descriptor: Beta-49 Fab heavy chain, Beta-49 Fab light chain, CHLORIDE ION, ...
Authors:Zhou, D, Ren, J, Stuart, D.I.
Deposit date:2021-10-14
Release date:2021-12-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.
Cell Host Microbe, 30, 2022
7PKD
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BU of 7pkd by Molmil
C-reactive protein decamer at pH 7.5 with phosphocholine ligand
Descriptor: C-reactive protein, CALCIUM ION, PHOSPHOCHOLINE
Authors:Noone, D.P, Sharp, T.H.
Deposit date:2021-08-25
Release date:2021-12-22
Last modified:2022-01-12
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-Electron Microscopy and Biochemical Analysis Offer Insights Into the Effects of Acidic pH, Such as Occur During Acidosis, on the Complement Binding Properties of C-Reactive Protein.
Front Immunol, 12, 2021
3GIT
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BU of 3git by Molmil
Crystal structure of a truncated acetyl-CoA synthase
Descriptor: Carbon monoxide dehydrogenase/acetyl-CoA synthase subunit alpha, GLYCEROL, HYDROSULFURIC ACID, ...
Authors:Volbeda, A, Darnault, C, Fontecilla-Camps, J.C.
Deposit date:2009-03-06
Release date:2009-10-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Novel domain arrangement in the crystal structure of a truncated acetyl-CoA synthase from Moorella thermoacetica
Biochemistry, 48, 2009
2R9G
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BU of 2r9g by Molmil
Crystal structure of the C-terminal fragment of AAA ATPase from Enterococcus faecium
Descriptor: AAA ATPase, central region, ACETATE ION, ...
Authors:Ramagopal, U.A, Patskovsky, Y, Bonanno, J.B, Shi, W, Toro, R, Meyer, A.J, Rutter, M, Wu, B, Groshong, C, Gheyi, T, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-09-12
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal Structure of the C-Terminal Domain of AAA ATPase from Enterococcus faecium.
To be Published
7PKH
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BU of 7pkh by Molmil
C-reactive protein decamer at pH 5 with phosphocholine ligand
Descriptor: C-reactive protein, CALCIUM ION, PHOSPHOCHOLINE
Authors:Noone, D.P, Sharp, T.H.
Deposit date:2021-08-25
Release date:2021-12-22
Last modified:2022-01-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-Electron Microscopy and Biochemical Analysis Offer Insights Into the Effects of Acidic pH, Such as Occur During Acidosis, on the Complement Binding Properties of C-Reactive Protein.
Front Immunol, 12, 2021
2REX
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BU of 2rex by Molmil
Crystal structure of the effector domain of PLXNB1 bound with Rnd1 GTPase
Descriptor: CALCIUM ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Tong, Y, Tempel, W, Shen, L, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2007-09-27
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the effector domain of PLXNB1 bound with Rnd1 GTPase.
To be Published
7PTM
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BU of 7ptm by Molmil
Crystal Structure of Two-Domain Laccase mutant M199G/R240H from Streptomyces griseoflavus
Descriptor: COPPER (II) ION, GLYCEROL, OXYGEN MOLECULE, ...
Authors:Gabdulkhakov, A, Tishchenko, S, Kolyadenko, I.
Deposit date:2021-09-27
Release date:2022-01-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Engineering the Catalytic Properties of Two-Domain Laccase from Streptomyces griseoflavus Ac-993.
Int J Mol Sci, 23, 2021
7PXC
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BU of 7pxc by Molmil
Substrate-engaged mycobacterial Proteasome-associated ATPase in complex with open-gate 20S CP - composite map (state A)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Jomaa, A, Kavalchuk, M, Weber-Ban, E.
Deposit date:2021-10-08
Release date:2022-01-19
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex.
Nat Commun, 13, 2022
7PUH
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BU of 7puh by Molmil
Crystal Structure of Two-Domain Laccase mutant H165A/R240H from Streptomyces griseoflavus
Descriptor: 1,2-ETHANEDIOL, COPPER (II) ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Kolyadenko, I, Tishchenko, S, Gabdulkhakov, A.
Deposit date:2021-09-30
Release date:2022-01-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Engineering the Catalytic Properties of Two-Domain Laccase from Streptomyces griseoflavus Ac-993.
Int J Mol Sci, 23, 2021
7PXD
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BU of 7pxd by Molmil
Substrate-engaged mycobacterial Proteasome-associated ATPase in complex with open-gate 20S CP - composite map (state B)
Descriptor: AAA ATPase forming ring-shaped complexes, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Jomaa, A, Kavalchuk, M, Weber-Ban, E.
Deposit date:2021-10-08
Release date:2022-01-19
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex.
Nat Commun, 13, 2022
7Q21
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BU of 7q21 by Molmil
III2-IV2 respiratory supercomplex from Corynebacterium glutamicum
Descriptor: (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate, (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ...
Authors:Kovalova, T, Moe, A, Krol, S, Yanofsky, D.J, Bott, M, Sjostrand, D, Rubinstein, J.L, Hogbom, M, Brzezinski, P.
Deposit date:2021-10-22
Release date:2022-02-02
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The respiratory supercomplex from C. glutamicum.
Structure, 30, 2022
7PF1
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BU of 7pf1 by Molmil
UVC treated Human apoferritin
Descriptor: CHLORIDE ION, Ferritin heavy chain, N-terminally processed, ...
Authors:Renault, L, Depelteau, J.S, Briegel, A.
Deposit date:2021-08-11
Release date:2022-01-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:UVC inactivation of pathogenic samples suitable for cryo-EM analysis.
Commun Biol, 5, 2022
7Q3X
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BU of 7q3x by Molmil
Crystal structure of Malate dehydrogenase from Haloarcula marismortui with Potassium and Chloride ions
Descriptor: CHLORIDE ION, Malate dehydrogenase, POTASSIUM ION
Authors:Bertrand, Q, Roche, J, Girard, E, Madern, D.
Deposit date:2021-10-29
Release date:2022-02-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Resurrection of Ancestral Malate Dehydrogenases Reveals the Evolutionary History of Haloarchaeal Proteins.
To Be Published
7PUA
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BU of 7pua by Molmil
Middle assembly intermediate of the Trypanosoma brucei mitoribosomal small subunit
Descriptor: 30S Ribosomal protein S17, putative, 30S ribosomal protein S8, ...
Authors:Lenarcic, T, Leibundgut, M, Saurer, M, Ramrath, D.J.F, Fluegel, T, Boehringer, D, Ban, N.
Deposit date:2021-09-29
Release date:2022-03-02
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Mitoribosomal small subunit maturation involves formation of initiation-like complexes.
Proc.Natl.Acad.Sci.USA, 119, 2022
7Q0A
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BU of 7q0a by Molmil
SARS-CoV-2 Spike ectodomain with Fab FI3A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FI3A fab Light chain, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
Deposit date:2021-10-14
Release date:2022-02-23
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2.
Theranostics, 12, 2022

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