8SM7
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3GVK
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![BU of 3gvk by Molmil](/molmil-images/mine/3gvk) | Crystal structure of endo-neuraminidase NF mutant | Descriptor: | Endo-N-acetylneuraminidase, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-beta-neuraminic acid, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-beta-neuraminic acid, ... | Authors: | Schulz, E.C, Dickmanns, A, Ficner, R. | Deposit date: | 2009-03-31 | Release date: | 2010-03-02 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structural basis for the recognition and cleavage of polysialic acid by the bacteriophage K1F tailspike protein EndoNF. J.Mol.Biol., 397, 2010
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8RDP
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![BU of 8rdp by Molmil](/molmil-images/mine/8rdp) | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with spiro-isoxazol based compound 8a | Descriptor: | (5~{S})-3-(2-chlorophenyl)-1-oxa-2,9-diazaspiro[4.5]dec-2-ene-8,10-dione, Cereblon isoform 4, PHOSPHATE ION, ... | Authors: | Bischof, L, Hartmann, M.D. | Deposit date: | 2023-12-08 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode. Eur.J.Med.Chem., 270, 2024
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7QHJ
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![BU of 7qhj by Molmil](/molmil-images/mine/7qhj) | Peptide GAKSAA in complex with human cathepsin V C25A mutant | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Cathepsin L2, ... | Authors: | Loboda, J, Sosnowski, P, Tusar, L, Vidmar, R, Vizovisek, M, Horvat, J, Kosec, G, Impens, F, Demol, H, Turk, B, Gevaert, K, Turk, D. | Deposit date: | 2021-12-13 | Release date: | 2022-12-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins. Commun Biol, 6, 2023
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8SGB
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7QLH
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![BU of 7qlh by Molmil](/molmil-images/mine/7qlh) | Crystal structure of S-layer protein SlpA from Lactobacillus amylovorus, domain I (aa 48-213) | Descriptor: | PHOSPHATE ION, S-layer, SODIUM ION | Authors: | Grininger, C, Sagmeister, T, Eder, E, Vejzovic, D, Pavkov-Keller, T. | Deposit date: | 2021-12-20 | Release date: | 2022-12-28 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The molecular architecture of Lactobacillus S-layer: Assembly and attachment to teichoic acids. Proc.Natl.Acad.Sci.USA, 121, 2024
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7QKB
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![BU of 7qkb by Molmil](/molmil-images/mine/7qkb) | Crystal structure of human Cathepsin L in complex with covalently bound GC376 | Descriptor: | CHLORIDE ION, Cathepsin L, DI(HYDROXYETHYL)ETHER, ... | Authors: | Reinke, P.Y.A, Falke, S, Lieske, J, Ewert, W, Loboda, J, Rahmani Mashhour, A, Hauser, M, Karnicar, K, Usenik, A, Lindic, N, Lach, M, Boehler, H, Beck, T, Cox, R, Chapman, H.N, Hinrichs, W, Turk, D, Guenther, S, Meents, A. | Deposit date: | 2021-12-17 | Release date: | 2022-12-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections. Commun Biol, 6, 2023
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7LM5
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![BU of 7lm5 by Molmil](/molmil-images/mine/7lm5) | Crystal structure of the Zn(II)-bound AdcAII H65A mutant variant of Streptococcus pneumoniae | Descriptor: | Adhesion protein, CHLORIDE ION, SODIUM ION, ... | Authors: | Luo, Z, Zupan, M, McDevitt, C.A, Kobe, B. | Deposit date: | 2021-02-05 | Release date: | 2021-09-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Conformation of the Solute-Binding Protein AdcAII Influences Zinc Uptake in Streptococcus pneumoniae . Front Cell Infect Microbiol, 11, 2021
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3HAB
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![BU of 3hab by Molmil](/molmil-images/mine/3hab) | The structure of DPP4 in complex with piperidine fused benzimidazole 25 | Descriptor: | (2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Scapin, G. | Deposit date: | 2009-05-01 | Release date: | 2009-07-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Aminopiperidine-fused imidazoles as dipeptidyl peptidase-IV inhibitors Bioorg.Med.Chem.Lett., 19, 2009
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8SBF
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![BU of 8sbf by Molmil](/molmil-images/mine/8sbf) | Full-length structure of the LysR-type transcriptional regulator, ACIAD0746, from Acinetobacter baylyi | Descriptor: | GLYCEROL, MAGNESIUM ION, Putative transcriptional regulator (LysR family), ... | Authors: | Momany, C, Nune, M, Brondani, J.C, Afful, D, Neidle, E, Galloway, N.R. | Deposit date: | 2023-04-03 | Release date: | 2024-04-17 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | FinR, a LysR-type transcriptional regulator involved in sulfur homeostasis with homologs in diverse microorganisms To Be Published
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5H8I
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![BU of 5h8i by Molmil](/molmil-images/mine/5h8i) | Crystal structure of Medicago truncatula N-carbamoylputrescine amidohydrolase (MtCPA) in complex with N-(dihydroxymethyl)putrescine | Descriptor: | (4-azanylbutylamino)methanediol, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Sekula, B, Ruszkowski, M, Malinska, M, Dauter, Z. | Deposit date: | 2015-12-23 | Release date: | 2016-04-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural Investigations of N-carbamoylputrescine Amidohydrolase from Medicago truncatula: Insights into the Ultimate Step of Putrescine Biosynthesis in Plants. Front Plant Sci, 7, 2016
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7LU6
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![BU of 7lu6 by Molmil](/molmil-images/mine/7lu6) | Crystal structure of the mouse Kirrel3 D1 homodimer | Descriptor: | Kin of IRRE-like protein 3, SODIUM ION | Authors: | Roman, C.A, Pak, J.S, Wang, J, Ozkan, E. | Deposit date: | 2021-02-21 | Release date: | 2021-11-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors. Cell Rep, 37, 2021
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7LTW
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![BU of 7ltw by Molmil](/molmil-images/mine/7ltw) | Crystal structure of the mouse Kirrel2 D1 homodimer | Descriptor: | Kin of IRRE-like protein 2, SODIUM ION | Authors: | Roman, C.A, Pak, J.S, Wang, J, Ozkan, E. | Deposit date: | 2021-02-20 | Release date: | 2021-11-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors. Cell Rep, 37, 2021
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7QTD
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![BU of 7qtd by Molmil](/molmil-images/mine/7qtd) | Crystal Structure of the Fe(II)/alpha-ketoglutarate dependent dioxygenase PlaO1 in complex with iron and alpha-ketoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, ACETATE ION, FE (II) ION, ... | Authors: | Lukat, P, Daum, M, Bechthold, A, Einsle, O. | Deposit date: | 2022-01-14 | Release date: | 2023-01-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural investigations on the Fe(II)/alpha-ketoglutarate dependent dioxygense PlaO1 from Streptomyces sp. Tu6071 Thesis, 2011
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7QUV
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![BU of 7quv by Molmil](/molmil-images/mine/7quv) | Crystal structure of human Calprotectin (S100A8/S100A9) in complex with Peptide 3 | Descriptor: | 1,2-ETHANEDIOL, 4-methanoyl-2-(6-oxidanyl-3-oxidanylidene-4~{H}-xanthen-9-yl)benzoic acid, AMINO GROUP, ... | Authors: | Diaz-Perlas, C, Heinis, C, Pojer, F, Lau, K. | Deposit date: | 2022-01-19 | Release date: | 2023-02-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | High-affinity peptides developed against calprotectin and their application as synthetic ligands in diagnostic assays. Nat Commun, 14, 2023
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8SIG
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![BU of 8sig by Molmil](/molmil-images/mine/8sig) | Crystal Structure of PRMT4 with Compound YD1-288 | Descriptor: | 5'-{(3-aminopropyl)[2-(benzylcarbamamido)ethyl]amino}-5'-deoxyadenosine, Histone-arginine methyltransferase CARM1, SODIUM ION, ... | Authors: | Song, X, Dong, A, Deng, Y, Huang, R, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2023-04-16 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Crystal Structure of PRMT4 with Compound YD1-288 To be published
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7LA9
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7QTE
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![BU of 7qte by Molmil](/molmil-images/mine/7qte) | Crystal Structure of the Fe(II)/alpha-ketoglutarate dependent dioxygenase PlaO1 in complex with cobalt and succinate | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, COBALT (II) ION, PlaO1, ... | Authors: | Lukat, P, Daum, M, Bechthold, A, Einsle, O. | Deposit date: | 2022-01-14 | Release date: | 2023-01-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structural investigations on the Fe(II)/alpha-ketoglutarate dependent dioxygense PlaO1 from Streptomyces sp. Tu6071 Thesis, 2011
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6I9A
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![BU of 6i9a by Molmil](/molmil-images/mine/6i9a) | Porphyromonas gingivalis gingipain K (Kgp) in complex with inhibitor KYT-36 | Descriptor: | (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Gomis-Ruth, F.X, Guevara, T, Rofdriguez-Banqueri, A. | Deposit date: | 2018-11-22 | Release date: | 2019-03-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural determinants of inhibition of Porphyromonas gingivalis gingipain K by KYT-36, a potent, selective, and bioavailable peptidase inhibitor. Sci Rep, 9, 2019
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8RQQ
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![BU of 8rqq by Molmil](/molmil-images/mine/8rqq) | In meso structure of the adenosine A2a G protein-coupled receptor, A2aR, in 7.10 monoacylglycerol | Descriptor: | 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, 7.10 monoacylglycerol (R-form), 7.10 monoacylglycerol (S-form), ... | Authors: | Smithers, L, Krawinski, P, Caffrey, M. | Deposit date: | 2024-01-19 | Release date: | 2024-04-03 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | 7.10 MAG. A Novel Host Monoacylglyceride for In Meso (Lipid Cubic Phase) Crystallization of Membrane Proteins. Cryst.Growth Des., 24, 2024
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7QZ1
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![BU of 7qz1 by Molmil](/molmil-images/mine/7qz1) | Formate dehydrogenase from Starkeya novella | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Formate dehydrogenase, ... | Authors: | Pontillo, N, Slotboom, D.J, Guskov, A. | Deposit date: | 2022-01-30 | Release date: | 2023-02-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Biochemical and structural insight into the chemical resistance and cofactor specificity of the formate dehydrogenase from Starkeya novella. Febs J., 290, 2023
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7LSV
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3H4Z
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![BU of 3h4z by Molmil](/molmil-images/mine/3h4z) | Crystal Structure of an MBP-Der p 7 fusion protein | Descriptor: | Maltose-binding periplasmic protein fused with Allergen DERP7, SODIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Pedersen, L.C, Mueller, G.A, London, R.E. | Deposit date: | 2009-04-21 | Release date: | 2010-03-31 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The structure of the dust mite allergen Der p 7 reveals similarities to innate immune proteins. J.Allergy Clin.Immunol., 125, 2010
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7LNP
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7LJ2
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