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6DTA	Bacteriophage N4 RNA polymerase II elongation complex 2 Descriptor: DNA (5'-D(P*CP*CP*CP*AP*CP*CP*AP*AP*AP*AP*A)-3'), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Molodtsov, V, Murakami, K.S. Deposit date: 2018-06-15 Release date: 2018-07-11 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.694 Å) Cite: Minimalism and functionality: Structural lessons from the heterodimeric N4 bacteriophage RNA polymerase II. J. Biol. Chem., 293, 2018
6DT7	Bacteriophage N4 RNA polymerase II and DNA complex Descriptor: DNA (5'-D(P*CP*CP*AP*CP*CP*TP*GP*CP*A)-3'), RNAP1, RNAP2 Authors: Molodtsov, V, Murakami, K.S. Deposit date: 2018-06-15 Release date: 2018-07-11 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Minimalism and functionality: Structural lessons from the heterodimeric N4 bacteriophage RNA polymerase II. J. Biol. Chem., 293, 2018
4GWP	Structure of the Mediator Head Module from S. cerevisiae Descriptor: Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ... Authors: Robinson, P.J.J, Bushnell, D.A, Trnka, M.J, Burlingame, A.L, Kornberg, R.D. Deposit date: 2012-09-03 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (4.2 Å) Cite: Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II. Proc.Natl.Acad.Sci.USA, 109, 2012
4PN0	Structure of S. pombe Pct1 RNA triphosphatase Descriptor: mRNA-capping enzyme subunit beta Authors: Lima, C.D, Doamekpor, S.K. Deposit date: 2014-05-22 Release date: 2014-11-12 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Fission yeast RNA triphosphatase reads an Spt5 CTD code. Rna, 21, 2015
8UHA	Structure of paused transcription complex Pol II-DSIF-NELF - tilted Descriptor: DNA (28-MER), DNA (38-MER), DNA-directed RNA polymerase II subunit E, ... Authors: Vos, S.M, Su, B.G. Deposit date: 2023-10-08 Release date: 2024-03-20 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 2024
8UIS	Structure of transcription complex Pol II-DSIF-NELF-TFIIS Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... Authors: Su, B.G, Vos, S.M. Deposit date: 2023-10-10 Release date: 2024-03-20 Last modified: 2024-04-17 Method: ELECTRON MICROSCOPY (3.23 Å) Cite: Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 84, 2024
8UI0	Structure of poised transcription complex Pol II-DSIF-NELF - pre-translocated Descriptor: DNA, DNA (38-MER), DNA-directed RNA polymerase II subunit E, ... Authors: Vos, S.M, Su, B.G. Deposit date: 2023-10-09 Release date: 2024-03-20 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 2024
8UHD	Structure of paused transcription complex Pol II-DSIF-NELF - post-translocated Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... Authors: Su, B.G, Vos, S.M. Deposit date: 2023-10-08 Release date: 2024-03-20 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 2024
8UHG	Structure of paused transcription complex Pol II-DSIF-NELF - poised post-translocated Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Vos, S.M, Su, B.G. Deposit date: 2023-10-09 Release date: 2024-03-20 Last modified: 2024-04-17 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 84, 2024
6GYM	Structure of a yeast closed complex with distorted DNA (CCdist) Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. Deposit date: 2018-06-30 Release date: 2018-12-05 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (6.7 Å) Cite: Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
6GYL	Structure of a yeast closed complex with distorted DNA (core CCdist) Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. Deposit date: 2018-06-30 Release date: 2018-12-05 Last modified: 2019-12-11 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
6GYK	Structure of a yeast closed complex (core CC1) Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. Deposit date: 2018-06-30 Release date: 2018-12-05 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (5.1 Å) Cite: Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
8OEW	Structure of the mammalian Pol II-Elongin complex, lacking the ELOA latch (composite structure, structure 2) Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... Authors: Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. Deposit date: 2023-03-13 Release date: 2023-10-18 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
7MEI	Composite structure of EC+EC Descriptor: DNA (74-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Yang, C, Murakami, K. Deposit date: 2021-04-06 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (3.54 Å) Cite: Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. Mol.Cell, 82, 2022
7MKA	Structure of EC+EC (leading EC-focused) Descriptor: DNA (40-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Yang, C, Murakami, K. Deposit date: 2021-04-22 Release date: 2022-04-27 Last modified: 2023-05-17 Method: ELECTRON MICROSCOPY (3.54 Å) Cite: Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. Mol.Cell, 82, 2022
7MK9	Complex structure of trailing EC of EC+EC (trailing EC-focused) Descriptor: DNA (40-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Yang, C, Murakami, K. Deposit date: 2021-04-22 Release date: 2022-04-27 Last modified: 2023-05-17 Method: ELECTRON MICROSCOPY (3.54 Å) Cite: Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. Mol.Cell, 82, 2022
8OEU	Structure of the mammalian Pol II-SPT6 complex (composite structure, Structure 4) Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... Authors: Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. Deposit date: 2023-03-13 Release date: 2023-10-18 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (3.04 Å) Cite: Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
8OF0	Structure of the mammalian Pol II-SPT6-Elongin complex, Structure 1 Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... Authors: Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. Deposit date: 2023-03-13 Release date: 2023-10-18 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (3.05 Å) Cite: Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
8OEV	Structure of the mammalian Pol II-SPT6-Elongin complex, lacking ELOA latch (composite structure, structure 3) Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... Authors: Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. Deposit date: 2023-03-13 Release date: 2023-10-18 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (2.86 Å) Cite: Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
7O4L	Yeast TFIIH in the expanded state within the pre-initiation complex Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... Authors: Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. Deposit date: 2021-04-06 Release date: 2021-06-16 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening. Cell, 184, 2021
7O4K	Yeast TFIIH in the contracted state within the pre-initiation complex Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... Authors: Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. Deposit date: 2021-04-06 Release date: 2021-06-16 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening. Cell, 184, 2021
3J1N	Cryo-EM map of a yeast minimal preinitiation complex interacting with the Mediator Head module Descriptor: DNA-directed RNA polymerase II subunit RPABC1, DNA-directed RNA polymerase II subunit RPABC2, DNA-directed RNA polymerase II subunit RPABC3, ... Authors: Asturias, F.J, Imasaki, T. Deposit date: 2012-03-29 Release date: 2013-03-06 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (16 Å) Cite: Interaction of the mediator head module with RNA polymerase II. Structure, 20, 2012
3H3V	Yeast RNAP II containing poly(A)-signal sequence in the active site Descriptor: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*GP*CP*TP*GP*CP*TP*TP*TP*AP*TP*TP*GP*CP*AP*TP*T)-3', 5'-D(*CP*AP*GP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*UP*CP*GP*CP*AP*AP*UP*AP*AP*A)-3', ... Authors: Dengl, S, Cramer, P. Deposit date: 2009-04-17 Release date: 2009-06-16 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (4 Å) Cite: Torpedo Nuclease Rat1 Is Insufficient to Terminate RNA Polymerase II in Vitro J.Biol.Chem., 284, 2009
8PNP	Influenza A/H7N9 polymerase in pre-initiation state with continuous Pol II pS5 CTD peptide mimic bound in site 1A/2A Descriptor: 51-mer vRNA loop (v51_mut_S), Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Arragain, B, Cusack, S. Deposit date: 2023-06-30 Release date: 2024-02-21 Method: ELECTRON MICROSCOPY (2.49 Å) Cite: The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8PNQ	Influenza A/H7N9 polymerase in elongation state with continuous Pol II pS5 CTD peptide mimic bound in site 1A/2A Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, 51-mer vRNA loop (v51_mut_S), MAGNESIUM ION, ... Authors: Arragain, B, Cusack, S. Deposit date: 2023-06-30 Release date: 2024-02-21 Method: ELECTRON MICROSCOPY (2.88 Å) Cite: The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024

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