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PDB: 13 件
4BBN
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BU of 4bbn by Molmil
NEDD4 HECT-Ub:Ub complex
分子名称: E3 UBIQUITIN-PROTEIN LIGASE NEDD4, POLYUBIQUITIN-B
著者Maspero, E, Valentini, E, Mari, S, Cecatiello, V, Polo, S, Pasqualato, S.
登録日2012-09-27
公開日2013-05-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure of a Ubiquitin-Loaded Hect Ligase Reveals the Molecular Basis for Catalytic Priming
Nat.Struct.Mol.Biol., 20, 2013
2XBF
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Nedd4 HECT structure
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE NEDD4
著者Maspero, E, Cecatiello, V, Musacchio, A, Polo, S, Pasqualato, S.
登録日2010-04-09
公開日2011-03-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献Structure of the Hect:Ubiquitin Complex and its Role in Ubiquitin Chain Elongation
Embo Rep., 12, 2011
3B7Y
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BU of 3b7y by Molmil
Crystal structure of the C2 Domain of the E3 Ubiquitin-Protein Ligase NEDD4
分子名称: CALCIUM ION, E3 ubiquitin-protein ligase NEDD4
著者Walker, J.R, Ruzanov, M, Butler-Cole, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-10-31
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献C2 Domain of the Human E3 Ubiquitin-Protein Ligase NEDD4.
To be Published
4N7H
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Crystal Structure of the Complex of 3rd WW domain of Human Nedd4 and 1st PPXY Motif of ARRDC3
分子名称: Arrestin domain-containing protein 3, E3 ubiquitin-protein ligase NEDD4, GUANIDINE
著者Qi, S, O'Hayre, M, Gutkind, J.S, Hurley, J.
登録日2013-10-15
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3).
J.Biol.Chem., 289, 2014
4N7F
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BU of 4n7f by Molmil
Crystal structure of 3rd WW domain of human Nedd4-1
分子名称: E3 ubiquitin-protein ligase NEDD4
著者Qi, S, O'Hayre, M, Gutkind, J.S, Hurley, J.
登録日2013-10-15
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.102 Å)
主引用文献Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3).
J.Biol.Chem., 289, 2014
4BE8
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BU of 4be8 by Molmil
NEDD4 HECT A889F structure
分子名称: E3 UBIQUITIN-PROTEIN LIGASE NEDD4
著者Maspero, E, Valentini, E, Mari, S, Cecatiello, V, Polo, S, Pasqualato, S.
登録日2013-03-06
公開日2013-05-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.996 Å)
主引用文献Structure of a Ubiquitin-Loaded Hect Ligase Reveals the Molecular Basis for Catalytic Priming
Nat.Struct.Mol.Biol., 20, 2013
2XBB
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BU of 2xbb by Molmil
Nedd4 HECT:Ub complex
分子名称: E3 UBIQUITIN-PROTEIN LIGASE NEDD4, GLYCEROL, UBIQUITIN
著者Maspero, E, Cecatiello, V, Musacchio, A, Polo, S, Pasqualato, S.
登録日2010-04-08
公開日2011-03-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Structure of the Hect:Ubiquitin Complex and its Role in Ubiquitin Chain Elongation
Embo Rep., 12, 2011
5AHT
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BU of 5aht by Molmil
Third WW domain from the E3 ubiquitin-protein ligase NEDD4
分子名称: E3 UBIQUITIN-PROTEIN LIGASE NEDD4
著者Panwalkar, V, Lecher, J, Dingley, A.
登録日2015-02-09
公開日2016-01-27
最終更新日2024-01-31
実験手法SOLUTION NMR
主引用文献The Nedd4-1 Ww Domain Recognizes the Py Motif Peptide Through Coupled Folding and Binding Equilibria.
Biochemistry, 55, 2016
2KPZ
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Human NEDD4 3RD WW Domain Complex with The Human T-cell Leukemia virus 1 GAG-Pro poliprotein Derived Peptide SDPQIPPPYVEP
分子名称: 12-mer from Gag-Pro polyprotein, E3 ubiquitin-protein ligase NEDD4
著者Iglesias-Bexiga, M, Macias, M, Bonet, R, Blanco, F.J, Cobos, E.S, Luque, I.
登録日2009-10-23
公開日2010-11-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Human NEDD4 3RD WW Domain Complex with Human T-cell Leukemia virus GAP-Pro Poliprotein Derived Peptide
To be Published
2KQ0
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Human NEDD4 3rd WW Domain Complex with Ebola Zaire Virus Matrix Protein VP40 Derived Peptide ILPTAPPEYMEA
分子名称: 12-mer from Matrix protein VP40, E3 ubiquitin-protein ligase NEDD4
著者Iglesias-Bexiga, M, Macias, M, Bonet, R, Blanco, F.J, Cobos, E.S, Luque, I.
登録日2009-10-23
公開日2010-11-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Human NEDD4 3rd WW Domain Complex with Ebola Zaire Virus Matrix Protein VP40 Derived Peptide
To be Published
5C7J
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BU of 5c7j by Molmil
CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT
分子名称: E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C
著者Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC)
登録日2015-06-24
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
5C91
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NEDD4 HECT with covalently bound indole-based inhibitor
分子名称: E3 ubiquitin-protein ligase NEDD4, methyl (2E)-4-{[(5-methoxy-1,2-dimethyl-1H-indol-3-yl)carbonyl]amino}but-2-enoate
著者Span, I, Smith, A.T, Kathman, S, Statsyuk, A.V, Rosenzweig, A.C.
登録日2015-06-26
公開日2015-09-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献A Small Molecule That Switches a Ubiquitin Ligase From a Processive to a Distributive Enzymatic Mechanism.
J. Am. Chem. Soc., 137, 2015
2M3O
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BU of 2m3o by Molmil
Structure and dynamics of a human Nedd4 WW domain-ENaC complex
分子名称: Amiloride-sensitive sodium channel subunit alpha, E3 ubiquitin-protein ligase NEDD4
著者Bobby, R, Medini, K, Neudecker, P, Lee, V, MacDonald, F.J, Brimble, M.A, Lott, J, Dingley, A.J.
登録日2013-01-23
公開日2013-08-28
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure and dynamics of human Nedd4-1 WW3 in complex with the alpha ENaC PY motif.
Biochim.Biophys.Acta, 1834, 2013

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件を2024-05-15に公開中

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