5V07
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![BU of 5v07 by Molmil](/molmil-images/mine/5v07) | Crystal structure of human exonuclease 1 Exo1 (D173A) in complex with 5' recessed-end DNA (rV) | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | Authors: | Shi, Y, Beese, L.S. | Deposit date: | 2017-02-28 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7MXV
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![BU of 7mxv by Molmil](/molmil-images/mine/7mxv) | |
5V0A
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![BU of 5v0a by Molmil](/molmil-images/mine/5v0a) | Crystal structure of human exonuclease 1 Exo1 (D225A) in complex with 5' recessed-end DNA (rVIII) | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(P*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), ... | Authors: | Shi, Y, Beese, L.S. | Deposit date: | 2017-02-28 | Release date: | 2017-05-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UZV
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![BU of 5uzv by Molmil](/molmil-images/mine/5uzv) | Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (rI) | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*C)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | Authors: | Shi, Y, Beese, L.S. | Deposit date: | 2017-02-27 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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3QE9
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![BU of 3qe9 by Molmil](/molmil-images/mine/3qe9) | Crystal structure of human exonuclease 1 Exo1 (D173A) in complex with DNA (complex I) | Descriptor: | CALCIUM ION, DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), ... | Authors: | Orans, J, McSweeney, E.A, Iyer, R.R, Hast, M.A, Hellinga, H.W, Modrich, P, Beese, L.S. | Deposit date: | 2011-01-20 | Release date: | 2011-04-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structures of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family. Cell(Cambridge,Mass.), 145, 2011
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5V0C
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![BU of 5v0c by Molmil](/molmil-images/mine/5v0c) | Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' flap DNA (f2I) | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*A)-3'), DNA (5'-D(P*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | Authors: | Shi, Y, Beese, L.S. | Deposit date: | 2017-02-28 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5V0D
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![BU of 5v0d by Molmil](/molmil-images/mine/5v0d) | Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' flap DNA (f2II) | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*AP*CP*TP*CP*A)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | Authors: | Shi, Y, Beese, L.S. | Deposit date: | 2017-02-28 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5V0B
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![BU of 5v0b by Molmil](/molmil-images/mine/5v0b) | Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (rIX) | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | Authors: | Shi, Y, Beese, L.S. | Deposit date: | 2017-02-28 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5V04
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![BU of 5v04 by Molmil](/molmil-images/mine/5v04) | Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (rII) | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | Authors: | Shi, Y, Beese, L.S. | Deposit date: | 2017-02-28 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5V0E
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![BU of 5v0e by Molmil](/molmil-images/mine/5v0e) | Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' flap DNA (f5I) | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*GP*AP*TP*AP*C)-3'), DNA (5'-D(P*CP*TP*CP*GP*TP*CP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | Authors: | Shi, Y, Beese, L.S. | Deposit date: | 2017-02-28 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.744 Å) | Cite: | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5V06
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![BU of 5v06 by Molmil](/molmil-images/mine/5v06) | Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (rIV) | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | Authors: | Shi, Y, Beese, L.S. | Deposit date: | 2017-02-28 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5V09
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5v09 by Molmil](/molmil-images/mine/5v09) | Crystal structure of human exonuclease 1 Exo1 (D225A) in complex with 5' recessed-end DNA (rVII) | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(P*AP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | Authors: | Shi, Y, Beese, L.S. | Deposit date: | 2017-02-28 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7MXS
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![BU of 7mxs by Molmil](/molmil-images/mine/7mxs) | |
5V08
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![BU of 5v08 by Molmil](/molmil-images/mine/5v08) | Crystal structure of human exonuclease 1 Exo1 (D173A) in complex with 5' recessed-end DNA (rVI) | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | Authors: | Shi, Y, Beese, L.S. | Deposit date: | 2017-02-28 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.812 Å) | Cite: | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7MXW
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![BU of 7mxw by Molmil](/molmil-images/mine/7mxw) | |
7MXX
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![BU of 7mxx by Molmil](/molmil-images/mine/7mxx) | |
5V05
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![BU of 5v05 by Molmil](/molmil-images/mine/5v05) | Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (rIII) | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | Authors: | Shi, Y, Beese, L.S. | Deposit date: | 2017-02-28 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.902 Å) | Cite: | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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3QEB
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![BU of 3qeb by Molmil](/molmil-images/mine/3qeb) | Crystal structure of human exonuclease 1 Exo1 (WT) in complex with DNA and Mn2+ (complex III) | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | Authors: | Orans, J, McSweeney, E.A, Iyer, R.R, Hast, M.A, Hellinga, H.W, Modrich, P, Beese, L.S. | Deposit date: | 2011-01-20 | Release date: | 2011-04-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family. Cell(Cambridge,Mass.), 145, 2011
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7MXU
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![BU of 7mxu by Molmil](/molmil-images/mine/7mxu) | |
7MXT
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![BU of 7mxt by Molmil](/molmil-images/mine/7mxt) | |
3QEA
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![BU of 3qea by Molmil](/molmil-images/mine/3qea) | Crystal structure of human exonuclease 1 Exo1 (WT) in complex with DNA (complex II) | Descriptor: | BARIUM ION, DNA (5'-D(P*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), ... | Authors: | Orans, J, McSweeney, E.A, Iyer, R.R, Hast, M.A, Hellinga, H.W, Modrich, P, Beese, L.S. | Deposit date: | 2011-01-20 | Release date: | 2011-04-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family. Cell(Cambridge,Mass.), 145, 2011
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7MXR
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![BU of 7mxr by Molmil](/molmil-images/mine/7mxr) | |
7MXQ
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![BU of 7mxq by Molmil](/molmil-images/mine/7mxq) | |