7MJA
 
 | | HLA-A*24:02 bound to Neuroblastoma derived PHOX2B peptide | | Descriptor: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | Authors: | Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G. | | Deposit date: | 2021-04-19 | | Release date: | 2021-08-18 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Nature, 599, 2021
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8EK5
 | | Engineered scFv 10LH bound to PHOX2B/HLA-A24:02 | | Descriptor: | 10LH single chain fragment variable (scFv), Beta-2-microglobulin, GLYCEROL, ... | | Authors: | Garfinkle, S.E, Florio, T.J, Sgourakis, N.G. | | Deposit date: | 2022-09-20 | | Release date: | 2023-12-06 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion.
Sci Immunol, 8, 2023
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8P7G
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8PUI
 | | human PHOX2B C-terminal domain including the polyA fragment at 298K | | Descriptor: | Paired mesoderm homeobox protein 2B | | Authors: | Anton, R, Trevino, M.A, Pantoja-Uceda, D, Felix, S, Babu, M, Cabrita, E.J, Zweckstetter, M, Tinnefeld, P, Vera, A.M, Oroz, J. | | Deposit date: | 2023-07-17 | | Release date: | 2024-03-13 | | Method: | SOLUTION NMR | | Cite: | Alternative low-populated conformations prompt phase transitions in polyalanine repeat expansions.
Nat Commun, 15, 2024
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8PTL
 | | human PHOX2B C-terminal domain including the polyA fragment at 278K | | Descriptor: | Paired mesoderm homeobox protein 2B | | Authors: | Anton, R, Trevino, M.A, Pantoja-Uceda, D, Felix, S, Babu, M, Cabrita, E.J, Zweckstetter, M, Tinnefeld, P, Vera, A.M, Oroz, J. | | Deposit date: | 2023-07-14 | | Release date: | 2024-03-13 | | Method: | SOLUTION NMR | | Cite: | Alternative low-populated conformations prompt phase transitions in polyalanine repeat expansions.
Nat Commun, 15, 2024
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