8PTL

human PHOX2B C-terminal domain including the polyA fragment at 278K

Summary for 8PTL

• Entry DOI: 10.2210/pdb8ptl/pdb
• NMR Information: BMRB: 51978
• Descriptor: Paired mesoderm homeobox protein 2B (1 entity in total)
• Functional Keywords: cchs, polya, homorepeat, trinucleotide repeat expansion, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 7535.39

Authors

Anton, R.,Trevino, M.A.,Pantoja-Uceda, D.,Felix, S.,Babu, M.,Cabrita, E.J.,Zweckstetter, M.,Tinnefeld, P.,Vera, A.M.,Oroz, J. (deposition date: 2023-07-14, release date: 2024-03-13)

• Primary citation: Anton, R.,Trevino, M.A.,Pantoja-Uceda, D.,Felix, S.,Babu, M.,Cabrita, E.J.,Zweckstetter, M.,Tinnefeld, P.,Vera, A.M.,Oroz, J.; Alternative low-populated conformations prompt phase transitions in polyalanine repeat expansions.; Nat Commun, 15:1925-1925, 2024; PubMed: 38431667; DOI: 10.1038/s41467-024-46236-5

Experimental method

SOLUTION NMR