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PDB: 8 results
5N8A
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BU of 5n8a by Molmil
Structure of RPA70N in complex with PrimPol (fragment 480-560)
Descriptor: DNA-directed primase/polymerase protein, Replication protein A 70 kDa DNA-binding subunit
Authors:Brissett, N.C, Doherty, A.J.
Deposit date:2017-02-23
Release date:2017-06-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Molecular basis for PrimPol recruitment to replication forks by RPA.
Nat Commun, 8, 2017
5N85
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BU of 5n85 by Molmil
Structure of RPA70N in complex with PrimPol (fragment 514-525)
Descriptor: DNA-directed primase/polymerase protein, Replication protein A 70 kDa DNA-binding subunit
Authors:Brissett, N.C, Doherty, A.J.
Deposit date:2017-02-23
Release date:2017-06-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for PrimPol recruitment to replication forks by RPA.
Nat Commun, 8, 2017
7JLG
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BU of 7jlg by Molmil
Human PrimPol extending from the erroneous primer base A opposite the 8-oxoguanine lesion
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Rechkoblit, O, Aggarwal, A.K.
Deposit date:2020-07-29
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase.
Nat Commun, 12, 2021
7JL8
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BU of 7jl8 by Molmil
Human PrimPol extending from the correct primer base C opposite the 8-oxoguanine lesion
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, ...
Authors:Rechkoblit, O, Aggarwal, A.K.
Deposit date:2020-07-29
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase.
Nat Commun, 12, 2021
5L2X
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BU of 5l2x by Molmil
Crystal structure of human PrimPol ternary complex
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*GP*GP*TP*AP*GP*CP*(DDG))-3'), ...
Authors:Rechkoblit, O, Gupta, Y.K, Malik, R, Rajashankar, K.R, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K.
Deposit date:2016-08-02
Release date:2016-11-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and mechanism of human PrimPol, a DNA polymerase with primase activity.
Sci Adv, 2, 2016
7JKL
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BU of 7jkl by Molmil
Human PrimPol misinserting dATP opposite the 8-oxoguanine lesion (3'-end base of the primer strand is 2',3'-dideoxy-terminated).
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*TP*GP*TP*GP*GP*TP*AP*GP*CP*(DDG))-3'), ...
Authors:Rechkoblit, O, Aggarwal, A.K.
Deposit date:2020-07-28
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.384 Å)
Cite:Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase.
Nat Commun, 12, 2021
7JKP
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BU of 7jkp by Molmil
Human PrimPol misinserting dATP opposite the 8-oxoguanine lesion
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*TP*GP*TP*GP*GP*TP*AP*GP*CP*G)-3'), ...
Authors:Rechkoblit, O, Aggarwal, A.K.
Deposit date:2020-07-28
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.592 Å)
Cite:Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase.
Nat Commun, 12, 2021
7JK1
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BU of 7jk1 by Molmil
Human PrimPol inserting correct dCTP opposite the 8-oxoguanine lesion
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Rechkoblit, O, Aggarwal, A.K.
Deposit date:2020-07-27
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase.
Nat Commun, 12, 2021

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