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PDB: 4 results

8QFZ
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BU of 8qfz by Molmil
TSLP-Bicycle complex
Descriptor: 1-[3,5-bis(3-bromanylpropanoyl)-1,3,5-triazinan-1-yl]-3-bromanyl-propan-1-one, CYS-HIS-TRP-LEU-GLU-ASN-CYS-TRP-ARG-GLY-PHE-CYS, Thymic stromal lymphopoietin
Authors:Petersen, J.
Deposit date:2023-09-05
Release date:2024-02-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Discovery and Characterization of a Bicyclic Peptide (Bicycle) Binder to Thymic Stromal Lymphopoietin.
J.Med.Chem., 67, 2024
5J13
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BU of 5j13 by Molmil
Structural basis for TSLP antagonism by the therapeutic antibody Tezepelumab (MEDI9929 / AMG-157)
Descriptor: SULFATE ION, Thymic stromal lymphopoietin, anti-TSLP Fab-fragment, ...
Authors:Verstraete, K, Savvides, S.N.
Deposit date:2016-03-28
Release date:2017-04-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma.
Nat Commun, 8, 2017
5J11
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BU of 5j11 by Molmil
Structure of human TSLP in complex with TSLPR and IL-7Ralpha
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor-like factor 2, Interleukin-7 receptor subunit alpha, ...
Authors:Verstraete, K, Savvides, S.N.
Deposit date:2016-03-28
Release date:2017-04-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma.
Nat Commun, 8, 2017
5J12
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BU of 5j12 by Molmil
Structure of human TSLP:TSLPR in complex with mouse IL-7Ralpha
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor-like factor 2, Interleukin-7 receptor subunit alpha, ...
Authors:Verstraete, K, Savvides, S.N.
Deposit date:2016-03-28
Release date:2017-04-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Structure of human TSLP:TSLPR in complex with mouse IL-7Ralpha
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222624

PDB entries from 2024-07-17

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