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PDB: 3 results

4QU3
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BU of 4qu3 by Molmil
GES-2 ertapenem acyl-enzyme complex
Descriptor: (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase GES-2, ...
Authors:Stewart, N.K, Smith, C.A, Frase, H, Black, D.J, Vakulenko, S.B.
Deposit date:2014-07-10
Release date:2014-12-31
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.402 Å)
Cite:Kinetic and Structural Requirements for Carbapenemase Activity in GES-Type beta-Lactamases.
Biochemistry, 54, 2015
3NIA
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BU of 3nia by Molmil
GES-2 carbapenemase tazobactam complex
Descriptor: (3S)-3-(dihydroxy-lambda~4~-sulfanyl)-4-(1H-1,2,3-triazol-1-yl)-D-valine, Beta-lactamase GES-2, TAZOBACTAM INTERMEDIATE
Authors:Frase, H, Smith, C.A, Toth, M, Vakulenko, S.B.
Deposit date:2010-06-15
Release date:2011-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Inhibition of the GES-2 beta-Lactamse by Tazobactam: Detection of Reaction Intermediates by UV and Mass Spectrometry and X-Ray Crystallography
To be Published
3NI9
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BU of 3ni9 by Molmil
GES-2 carbapenemase apo form
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase GES-2
Authors:Frase, H, Smith, C.A, Toth, M, Vakulenko, S.B.
Deposit date:2010-06-15
Release date:2011-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Kinetic and structural requirements for carbapenemase activity in GES-type beta-lactamases.
Biochemistry, 54, 2015

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