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PDB: 5 results

5VAK
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BU of 5vak by Molmil
Crystal Structure of Beta-Klotho, Domain 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-klotho, ...
Authors:Lee, S, Schlessinger, J.
Deposit date:2017-03-27
Release date:2018-01-31
Last modified:2021-03-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of beta-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling.
Nature, 553, 2018
5VAN
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BU of 5van by Molmil
Crystal Structure of Beta-Klotho
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lee, S, Schlessinger, J.
Deposit date:2017-03-27
Release date:2018-01-31
Last modified:2021-03-24
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Structures of beta-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling.
Nature, 553, 2018
5VAQ
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BU of 5vaq by Molmil
Crystal Structure of Beta-Klotho in Complex with FGF21CT
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-klotho, Fibroblast growth factor 21, ...
Authors:Lee, S, Schlessinger, J.
Deposit date:2017-03-27
Release date:2018-01-31
Last modified:2021-03-24
Method:X-RAY DIFFRACTION (2.606 Å)
Cite:Structures of beta-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling.
Nature, 553, 2018
5WI9
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BU of 5wi9 by Molmil
Crystal structure of KL with an agonist Fab
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 39F7 Fab heavy chain, ...
Authors:Johnstone, S, Min, X, Wang, Z.
Deposit date:2017-07-18
Release date:2018-07-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Agonistic beta-Klotho antibody mimics fibroblast growth factor 21 (FGF21) functions.
J. Biol. Chem., 293, 2018
6NFJ
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BU of 6nfj by Molmil
Structure of Beta-Klotho in Complex with FGF19 C-terminal peptide
Descriptor: Beta-klotho, Fibroblast growth factor 19, Nanobody 30
Authors:Kuzina, E, Schlessinger, J, Lee, S.
Deposit date:2018-12-20
Release date:2019-04-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structures of ligand-occupied beta-Klotho complexes reveal a molecular mechanism underlying endocrine FGF specificity and activity.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019

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