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PDB: 2 results

8EYR
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BU of 8eyr by Molmil
Cryo-EM structure of two IGF1 bound full-length mouse IGF1R mutant (four glycine residues inserted in the alpha-CT; IGF1R-P674G4): symmetric conformation
Descriptor: Insulin-like growth factor 1 receptor, Insulin-like growth factor I
Authors:Li, J, Wu, J.Y, Hall, C, Bai, X.C, Choi, E.
Deposit date:2022-10-28
Release date:2022-11-09
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
Elife, 11, 2022
6PYH
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BU of 6pyh by Molmil
Cryo-EM structure of full-length IGF1R-IGF1 complex. Only the extracellular region of the complex is resolved.
Descriptor: Insulin-like growth factor 1 receptor, Insulin-like growth factor I
Authors:Li, J, Choi, E, Yu, H.T, Bai, X.C.
Deposit date:2019-07-29
Release date:2019-10-23
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis of the activation of type 1 insulin-like growth factor receptor.
Nat Commun, 10, 2019

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