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PDB: 10 results

2RG8
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Crystal Structure of Programmed for Cell Death 4 Middle MA3 domain
Descriptor: CHLORIDE ION, Programmed cell death protein 4, SODIUM ION
Authors:Garces, R, Suzuki, C, Wagner, G.
Deposit date:2007-10-03
Release date:2008-03-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains.
Proc.Natl.Acad.Sci.Usa, 105, 2008
9BKD
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The structure of human Pdcd4 bound to the 40S small ribosomal subunit
Descriptor: 18S rRNA, 40S ribosomal protein S12, 40S ribosomal protein S13, ...
Authors:Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Zuber, P, Albacete-Albacete, L, Ramakrishnan, V, S.Fraser, C.
Deposit date:2024-04-27
Release date:2024-09-04
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit.
Nat Commun, 15, 2024
3EIJ
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Crystal structure of Pdcd4
Descriptor: Programmed cell death protein 4
Authors:Loh, P.G.
Deposit date:2008-09-16
Release date:2009-02-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for translational inhibition by the tumour suppressor Pdcd4
Embo J., 28, 2009
2ZU6
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crystal structure of the eIF4A-PDCD4 complex
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, Eukaryotic initiation factor 4A-I, ...
Authors:Cho, Y, Chang, J.H, Sohn, S.Y.
Deposit date:2008-10-13
Release date:2009-02-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the eIF4A-PDCD4 complex
Proc.Natl.Acad.Sci.Usa, 106, 2009
8XXL
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Cryo-EM structure of the human 40S ribosome with PDCD4
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J.
Deposit date:2024-01-18
Release date:2024-05-01
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 34, 2024
8XXM
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Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J.
Deposit date:2024-01-18
Release date:2024-05-01
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 34, 2024
8XXN
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Cryo-EM structure of the human 43S ribosome with PDCD4
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J.
Deposit date:2024-01-18
Release date:2024-05-01
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 34, 2024
9BLN
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The structure of human Pdcd4 bound to the 40S-eIF4A-eIF3-eIF1 complex
Descriptor: 40S ribosomal protein S14, ACETIC ACID, Eukaryotic initiation factor 4A-I, ...
Authors:Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Zuber, P, Yifei, D, Albacete-Albacete, L, Ramakrishnan, V, S Fraser, C.
Deposit date:2024-04-30
Release date:2024-09-04
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit.
Nat Commun, 15, 2024
2GGF
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Solution structure of the MA3 domain of human Programmed cell death 4
Descriptor: Programmed cell death 4, isoform 1
Authors:Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-03-24
Release date:2007-04-24
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the MA3 domain of human Programmed cell death 4
To be Published
2KZT
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Structure of the Tandem MA-3 Region of Pdcd4
Descriptor: Programmed cell death protein 4
Authors:Waters, L.C, Strong, S.L, Oka, O, Muskett, F.W, Veverka, V, Banerjee, S, Schmedt, T, Henry, A.J, Klempnauer, K.H, Carr, M.D.
Deposit date:2010-06-24
Release date:2011-03-16
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G: molecular mechanisms of a tumor suppressor
J.Biol.Chem., 286, 2011

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