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PDB: 10 results
7QI1
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BU of 7qi1 by Molmil
Crystal structure of human 14-3-3 protein beta in complex with CFTR peptide pS753pS768 and PPI stabilizer CY007424
Descriptor: 14-3-3 protein theta, ARGININE, Cystic fibrosis transmembrane conductance regulator, ...
Authors:Stevers, L.M, Ottmann, C.
Deposit date:2021-12-14
Release date:2022-05-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR.
Nat Commun, 13, 2022
6BCR
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BU of 6bcr by Molmil
Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at T340
Descriptor: 1,2-ETHANEDIOL, 14-3-3 protein theta, DI(HYDROXYETHYL)ETHER, ...
Authors:Kast, D.J, Dominguez, R.
Deposit date:2017-10-20
Release date:2018-10-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.986 Å)
Cite:Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
6KZG
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BU of 6kzg by Molmil
14-3-3 protein in Complex with CIC S301 phosphorylated peptide
Descriptor: 14-3-3 protein theta, ARG-SER-MET-SER-GLU-THR-GLY-THR
Authors:Wen, Y, Shao, Y.
Deposit date:2019-09-24
Release date:2020-09-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:14-3-3 protein in Complex with CIC S301 phosphorylated peptide
To Be Published
6BCY
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BU of 6bcy by Molmil
Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at T360
Descriptor: 14-3-3 protein theta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Kast, D.J, Dominguez, R.
Deposit date:2017-10-20
Release date:2018-10-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
6BD1
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BU of 6bd1 by Molmil
Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at S366
Descriptor: 14-3-3 protein theta, DI(HYDROXYETHYL)ETHER, Insulin receptor substrate protein of 53 kDa, ...
Authors:Kast, D.J, Dominguez, R.
Deposit date:2017-10-20
Release date:2018-10-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
5IQP
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BU of 5iqp by Molmil
14-3-3 PROTEIN TAU ISOFORM
Descriptor: 14-3-3 protein theta, SULFATE ION
Authors:Xiao, B, Smerdon, S.J, Gamblin, S.J.
Deposit date:2016-03-11
Release date:2016-03-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.602 Å)
Cite:Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways
Nature, 376, 1995
6KZH
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BU of 6kzh by Molmil
14-3-3 protein in Complex with CIC S173 phosphorylated peptide
Descriptor: 14-3-3 protein theta, CIC pS173 peptide
Authors:Wen, Y, Shao, Y.
Deposit date:2019-09-24
Release date:2020-09-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.645 Å)
Cite:14-3-3 protein in Complex with CIC S173 phosphorylated peptide
To Be Published
6BQT
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BU of 6bqt by Molmil
Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and T360
Descriptor: 1,2-ETHANEDIOL, 14-3-3 protein theta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ...
Authors:Kast, D.J, Dominguez, R.
Deposit date:2017-11-28
Release date:2018-12-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
2BTP
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BU of 2btp by Molmil
14-3-3 Protein Theta (Human) Complexed to Peptide
Descriptor: 14-3-3 PROTEIN TAU, CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS
Authors:Elkins, J.M, Johansson, A.C.E, Smee, C, Yang, X, Sundstrom, M, Edwards, A, Arrowsmith, C, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2005-06-05
Release date:2005-06-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
6BD2
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BU of 6bd2 by Molmil
Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and S366
Descriptor: 1,2-ETHANEDIOL, 14-3-3 protein theta, DI(HYDROXYETHYL)ETHER, ...
Authors:Kast, D.J, Dominguez, R.
Deposit date:2017-10-20
Release date:2018-10-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019

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