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PDB: 10 results

6GD3
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BU of 6gd3 by Molmil
Structure of HuR RRM3 in complex with RNA (UAUUUA)
Descriptor: ELAV-like protein 1, RNA (5'-R(P*UP*AP*UP*UP*UP*A)-3'), SODIUM ION
Authors:Pabis, M, Sattler, M.
Deposit date:2018-04-21
Release date:2018-10-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019
6GD2
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BU of 6gd2 by Molmil
Structure of HuR RRM3 in complex with RNA
Descriptor: ELAV-like protein 1, RNA (5'-R(P*UP*UP*UP*AP*UP*UP*U)-3')
Authors:Pabis, M, Sattler, M.
Deposit date:2018-04-21
Release date:2018-10-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019
6GC5
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BU of 6gc5 by Molmil
Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM
Descriptor: AU-rich RNA, ELAV-like protein 1
Authors:Ripin, N, Allain, F.H.
Deposit date:2018-04-17
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
4FXV
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BU of 4fxv by Molmil
Crystal structure of an ELAV-like protein 1 (ELAVL1) from Homo sapiens at 1.90 A resolution
Descriptor: ELAV-like protein 1
Authors:Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology, Partnership for T-Cell Biology (TCELL)
Deposit date:2012-07-03
Release date:2012-10-03
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of an ELAV-like protein 1 (ELAVL1) from Homo sapiens at 1.90 A resolution
To be published
4ED5
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BU of 4ed5 by Molmil
Crystal structure of the two N-terminal RRM domains of HuR complexed with RNA
Descriptor: 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, 5'-R(*A*UP*UP*UP*UP*UP*AP*UP*UP*UP*U)-3', ...
Authors:Wang, H, Zeng, F, Liu, Q, Niu, L, Teng, M, Li, X.
Deposit date:2012-03-27
Release date:2012-05-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA binding.
Acta Crystallogr.,Sect.D, 69, 2013
3HI9
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BU of 3hi9 by Molmil
The x-ray crystal structure of the first RNA recognition motif (RRM1) of the AU-rich element (ARE) binding protein HuR at 2.0 angstrom resolution
Descriptor: ELAV-like protein 1
Authors:Benoit, R.M, Kallen, J.
Deposit date:2009-05-19
Release date:2010-03-31
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:The X-ray Crystal Structure of the First RNA Recognition Motif and Site-Directed Mutagenesis Suggest a Possible HuR Redox Sensing Mechanism.
J.Mol.Biol., 397, 2010
6GD1
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BU of 6gd1 by Molmil
Structure of HuR RRM3
Descriptor: SODIUM ION, Thioredoxin 1,ELAV-like protein 1
Authors:Pabis, M, Sattler, M.
Deposit date:2018-04-21
Release date:2018-10-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019
6G2K
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BU of 6g2k by Molmil
Structure of HuR RRM3 in complex with RNA (UUUUUU)
Descriptor: ELAV-like protein 1, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), SULFATE ION
Authors:Pabis, M, Sattler, M.
Deposit date:2018-03-23
Release date:2018-10-31
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019
4EGL
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BU of 4egl by Molmil
Crystal structure of two tandem RNA recognition motifs of Human antigen R
Descriptor: ELAV-like protein 1, GLYCEROL, SULFATE ION
Authors:Wang, H, Zeng, F, Liu, H, Teng, M, Li, X.
Deposit date:2012-03-31
Release date:2012-05-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of two tandem RNA recognition motifs of Human antigen R
To be Published
5SZW
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BU of 5szw by Molmil
NMR solution structure of the RRM1 domain of the post-transcriptional regulator HuR
Descriptor: ELAV-like protein 1
Authors:Lixa, C, Mujo, A, Jendiroba, K.A, Almeida, F.C.L, Lima, L.M.T.R, Pinheiro, A.S.
Deposit date:2016-08-15
Release date:2017-09-06
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Oligomeric transition and dynamics of RNA binding by the HuR RRM1 domain in solution.
J. Biomol. NMR, 72, 2018

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