7UOO
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![BU of 7uoo by Molmil](/molmil-images/mine/7uoo) | Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | Authors: | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | Deposit date: | 2022-04-13 | Release date: | 2023-03-15 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.34 Å) | Cite: | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
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7V08
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![BU of 7v08 by Molmil](/molmil-images/mine/7v08) | Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a Spb1 D52A suppressor 3 strain | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | Authors: | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | Deposit date: | 2022-05-10 | Release date: | 2023-03-15 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.36 Å) | Cite: | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
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7UQB
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![BU of 7uqb by Molmil](/molmil-images/mine/7uqb) | Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1-D52A strain with AlF4 | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | Authors: | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | Deposit date: | 2022-04-19 | Release date: | 2023-03-15 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.43 Å) | Cite: | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
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7UQZ
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![BU of 7uqz by Molmil](/molmil-images/mine/7uqz) | Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1 D52A strain | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | Authors: | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | Deposit date: | 2022-04-20 | Release date: | 2023-03-15 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.44 Å) | Cite: | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
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8AAF
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![BU of 8aaf by Molmil](/molmil-images/mine/8aaf) | Yeast RQC complex in state G | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Tesina, P, Buschauer, R, Beckmann, R. | Deposit date: | 2022-07-01 | Release date: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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1G62
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![BU of 1g62 by Molmil](/molmil-images/mine/1g62) | CRYSTAL STRUCTURE OF S.CEREVISIAE EIF6 | Descriptor: | RIBOSOME ANTI-ASSOCIATION FACTOR EIF6 | Authors: | Groft, C.M, Beckmann, R, Sali, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2000-11-02 | Release date: | 2000-11-22 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of ribosome anti-association factor IF6. Nat.Struct.Biol., 7, 2000
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8V83
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![BU of 8v83 by Molmil](/molmil-images/mine/8v83) | 60S ribosome biogenesis intermediate (Dbp10 pre-catalytic structure - Overall map) | Descriptor: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... | Authors: | Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. | Deposit date: | 2023-12-04 | Release date: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.53 Å) | Cite: | The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024
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8AGW
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![BU of 8agw by Molmil](/molmil-images/mine/8agw) | Yeast RQC complex in state D | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Tesina, P, Buschauer, R, Beckmann, R. | Deposit date: | 2022-07-20 | Release date: | 2023-03-08 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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8AGT
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![BU of 8agt by Molmil](/molmil-images/mine/8agt) | Yeast RQC complex in state F | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Tesina, P, Buschauer, R, Beckmann, R. | Deposit date: | 2022-07-20 | Release date: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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8AGZ
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![BU of 8agz by Molmil](/molmil-images/mine/8agz) | Yeast RQC complex in state with the RING domain of Ltn1 in the OUT position | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Tesina, P, Buschauer, R, Beckmann, R. | Deposit date: | 2022-07-20 | Release date: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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8AGV
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![BU of 8agv by Molmil](/molmil-images/mine/8agv) | Yeast RQC complex in state H | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Tesina, P, Buschauer, R, Beckmann, R. | Deposit date: | 2022-07-20 | Release date: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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8HFR
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![BU of 8hfr by Molmil](/molmil-images/mine/8hfr) | NPC-trapped pre-60S particle | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Li, Z.Q, Chen, S.J, Sui, S.F. | Deposit date: | 2022-11-12 | Release date: | 2023-04-12 | Last modified: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (2.64 Å) | Cite: | Nuclear export of pre-60S particles through the nuclear pore complex. Nature, 618, 2023
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8V87
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![BU of 8v87 by Molmil](/molmil-images/mine/8v87) | 60S ribosome biogenesis intermediate (Dbp10 post-catalytic structure - Overall map) | Descriptor: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | Authors: | Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. | Deposit date: | 2023-12-04 | Release date: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024
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8V84
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![BU of 8v84 by Molmil](/molmil-images/mine/8v84) | 60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map) | Descriptor: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... | Authors: | Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. | Deposit date: | 2023-12-04 | Release date: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024
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8AGU
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![BU of 8agu by Molmil](/molmil-images/mine/8agu) | Yeast RQC complex in state E | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Tesina, P, Buschauer, R, Beckmann, R. | Deposit date: | 2022-07-20 | Release date: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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7U0H
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![BU of 7u0h by Molmil](/molmil-images/mine/7u0h) | State NE1 nucleolar 60S ribosome biogenesis intermediate - Overall model | Descriptor: | 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ... | Authors: | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | Deposit date: | 2022-02-18 | Release date: | 2022-12-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
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7UG6
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![BU of 7ug6 by Molmil](/molmil-images/mine/7ug6) | Cryo-EM structure of pre-60S ribosomal subunit, unmethylated G2922 | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Yelland, J.N, Bravo, J.P.K, Black, J.J.B, Taylor, D.W, Johnson, A.W. | Deposit date: | 2022-03-24 | Release date: | 2022-12-21 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | A single 2'-O-methylation of ribosomal RNA gates assembly of a functional ribosome. Nat.Struct.Mol.Biol., 30, 2023
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6YLG
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![BU of 6ylg by Molmil](/molmil-images/mine/6ylg) | |
7R7A
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![BU of 7r7a by Molmil](/molmil-images/mine/7r7a) | State E1 nucleolar 60S ribosome biogenesis intermediate - Composite model | Descriptor: | 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | Authors: | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | Deposit date: | 2021-06-24 | Release date: | 2022-11-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
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7NAC
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![BU of 7nac by Molmil](/molmil-images/mine/7nac) | State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model | Descriptor: | 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | Authors: | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | Deposit date: | 2021-06-21 | Release date: | 2022-11-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
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5H4P
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![BU of 5h4p by Molmil](/molmil-images/mine/5h4p) | Structural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1 | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Ma, C, Wu, S, Li, N, Chen, Y, Yan, K, Li, Z, Zheng, L, Lei, J, Woolford, J.L, Gao, N. | Deposit date: | 2016-11-01 | Release date: | 2017-01-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Structural snapshot of cytoplasmic pre-60S ribosomal particles bound by Nmd3, Lsg1, Tif6 and Reh1 Nat. Struct. Mol. Biol., 24, 2017
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3JCT
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![BU of 3jct by Molmil](/molmil-images/mine/3jct) | Cryo-em structure of eukaryotic pre-60S ribosomal subunits | Descriptor: | 60S ribosomal protein L11-A, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... | Authors: | Wu, S, Kumcuoglu, B, Yan, K.G, Brown, H, Zhang, Y.X, Tan, D, Gamalinda, M, Yuan, Y, Li, Z.F, Jakovljevic, J, Ma, C.Y, Lei, J.L, Dong, M.Q, Woolford Jr, J.L, Gao, N. | Deposit date: | 2016-03-09 | Release date: | 2016-06-01 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes Nature, 534, 2016
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7OHQ
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![BU of 7ohq by Molmil](/molmil-images/mine/7ohq) | |
7OF1
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![BU of 7of1 by Molmil](/molmil-images/mine/7of1) | |
6QIK
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![BU of 6qik by Molmil](/molmil-images/mine/6qik) | |