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PDB: 13 results

6YJS
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BU of 6yjs by Molmil
Crystal structure of MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase V) luminal domain with a Lys329-Ile345 loop truncation, in complex with biantennary pentasaccharide M592
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, ...
Authors:Wu, L, Darby, J.F, Gilio, A.K, Davies, G.J.
Deposit date:2020-04-04
Release date:2020-08-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
Acs Catalysis, 2020
6YJT
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BU of 6yjt by Molmil
Crystal structure of MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase V) luminal domain with a Lys329-Ile345 loop truncation, in complex with UDP
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, ...
Authors:Wu, L, Darby, J.F, Gilio, A.K, Davies, G.J.
Deposit date:2020-04-04
Release date:2020-08-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
Acs Catalysis, 2020
6YJV
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BU of 6yjv by Molmil
Crystal structure of unliganded MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase V) luminal domain with a Lys329-Ile345 loop truncation, in complex with UDP-2-deoxy-2-fluoroglucose and biantennary pentasaccharide M592
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose, ...
Authors:Wu, L, Darby, J.F, Gilio, A.K, Davies, G.J.
Deposit date:2020-04-04
Release date:2020-08-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
Acs Catalysis, 2020
8CE3
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BU of 8ce3 by Molmil
Crystal structure of MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase V) luminal domain with a Lys329-Ile345 loop truncation, in complex with 3D fragment 2548
Descriptor: (3~{S})-1-ethanoyl-3-(4-methylphenyl)piperidine-3-carboxylic acid, 1,2-ETHANEDIOL, Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, ...
Authors:Gilio, A.K, Darby, J.F, Wu, L, Davies, G.J.
Deposit date:2023-02-01
Release date:2024-02-21
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:A Modular 3-D Fragment Collection: Design, Synthesis and Screening
To Be Published
6YJQ
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BU of 6yjq by Molmil
Crystal structure of unliganded MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase V) luminal domain with a Lys329-Ile345 loop truncation
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A,Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, ...
Authors:Wu, L, Darby, J.F, Gilio, A.K, Davies, G.J.
Deposit date:2020-04-04
Release date:2020-08-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
Acs Catalysis, 2020
5ZIB
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BU of 5zib by Molmil
Crystal structure of human GnT-V luminal domain in apo form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
Authors:Nagae, M, Yamaguchi, Y.
Deposit date:2018-03-14
Release date:2018-08-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V.
Nat Commun, 9, 2018
6YJU
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BU of 6yju by Molmil
Crystal structure of MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase V) luminal domain with a Lys329-Ile345 loop truncation, in complex with UDP and biantennary pentasaccharide M592
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose, ...
Authors:Wu, L, Darby, J.F, Gilio, A.K, Davies, G.J.
Deposit date:2020-04-04
Release date:2020-08-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
Acs Catalysis, 2020
5ZIC
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BU of 5zic by Molmil
Crystal structure of human GnT-V luminal domain in complex with acceptor sugar
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-6-thio-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose, Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
Authors:Nagae, M, Yamaguchi, Y.
Deposit date:2018-03-14
Release date:2018-08-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V.
Nat Commun, 9, 2018
6YJR
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BU of 6yjr by Molmil
Crystal structure of unliganded MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase V) luminal domain.
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, ...
Authors:Wu, L, Darby, J.F, Gilio, A.K, Davies, G.J.
Deposit date:2020-04-04
Release date:2020-08-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
Acs Catalysis, 2020
7YYI
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BU of 7yyi by Molmil
Solution NMR structure of N-acetylglucosaminyltransferase V (GnTV) TMD
Descriptor: Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
Authors:Silber, M, Muhle-Goll, C.
Deposit date:2022-02-17
Release date:2022-12-28
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage.
Sci Rep, 12, 2022
7Z07
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BU of 7z07 by Molmil
Solution NMR structure of N-acetylglucosaminyltransferase V (GnTV) G26P mutant TMD
Descriptor: Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
Authors:Silber, M, Muhle-Goll, C.
Deposit date:2022-02-22
Release date:2022-12-28
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage.
Sci Rep, 12, 2022
7Z08
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BU of 7z08 by Molmil
Solution NMR structure of N-acetylglucosaminyltransferase V (GnTV) G22L mutant TMD
Descriptor: Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
Authors:Silber, M, Muhle-Goll, C.
Deposit date:2022-02-22
Release date:2022-12-28
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage.
Sci Rep, 12, 2022
7Z0B
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BU of 7z0b by Molmil
Solution NMR structure of N-acetylglucosaminyltransferase V (GnTV) G22L and G26L double mutant TMD
Descriptor: Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
Authors:Silber, M, Muhle-Goll, C.
Deposit date:2022-02-22
Release date:2022-12-28
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage.
Sci Rep, 12, 2022

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