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PDB: 18 results

1EAQ
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BU of 1eaq by Molmil
The RUNX1 Runt domain at 1.25A resolution: A structural switch and specifically bound chloride ions modulate DNA binding
Descriptor: CHLORIDE ION, RUNT-RELATED TRANSCRIPTION FACTOR 1
Authors:Backstrom, S, Wolf-Watz, M, Grundstrom, C, Hard, T, Grundstrom, T, Sauer, U.H.
Deposit date:2001-07-14
Release date:2002-09-12
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The Runx1 Runt Domain at 1.25 A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate DNA Binding
J.Mol.Biol., 322, 2002
1EAO
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BU of 1eao by Molmil
THE RUNX1 Runt domain at 1.4A resolution: a structural switch and specifically bound chloride ions modulate DNA binding
Descriptor: BROMIDE ION, RUNT-RELATED TRANSCRIPTION FACTOR 1
Authors:Backstrom, S, Wolf-Watz, M, Grundstrom, C, Hard, T.H, Grundstrom, T, Sauer, U.H.
Deposit date:2001-07-14
Release date:2002-09-12
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Runx1 Runt Domain at 1.25A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate DNA Binding
J.Mol.Biol., 322, 2002
1EAN
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BU of 1ean by Molmil
THE RUNX1 Runt domain at 1.70A resolution: A structural switch and specifically bound chloride ions modulate DNA binding
Descriptor: CHLORIDE ION, RUNT-RELATED TRANSCRIPTION FACTOR 1
Authors:Backstrom, S, Wolf-Watz, M, Grundstrom, C, Hard, T, Grundstrom, T, Sauer, U.H.
Deposit date:2001-07-13
Release date:2002-09-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Runx1 Runt Domain at 1.25 A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate DNA Binding
J.Mol.Biol., 322, 2002
4L18
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BU of 4l18 by Molmil
Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 3)
Descriptor: 5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', GLYCEROL, ...
Authors:Tahirov, T.H.
Deposit date:2013-06-02
Release date:2014-03-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of Ets1 activation by Runx1.
Leukemia, 28, 2014
3WTT
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BU of 3wtt by Molmil
Crystal structure of the complex comprised of phosphorylated ETS1, RUNX1, CBFBETA, and the tcralpha gene enhancer DNA
Descriptor: 5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Core-binding factor subunit beta, ...
Authors:Shiina, M, Hamada, K, Ogata, K.
Deposit date:2014-04-21
Release date:2014-08-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
3WTS
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BU of 3wts by Molmil
Crystal structure of the complex comprised of ETS1, RUNX1, CBFBETA, and the tcralpha gene enhancer DNA
Descriptor: 5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Core-binding factor subunit beta, ...
Authors:Shiina, M, Hamada, K, Ogata, K.
Deposit date:2014-04-21
Release date:2014-08-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
3WU1
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BU of 3wu1 by Molmil
Crystal structure of the ETS1-RUNX1-DNA ternary complex
Descriptor: DNA (5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), Protein C-ets-1, ...
Authors:Tahirov, T.H, Ogata, K.
Deposit date:2014-04-21
Release date:2014-08-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
4L0Y
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BU of 4l0y by Molmil
Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 1)
Descriptor: 5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Protein C-ets-1, ...
Authors:Tahirov, T.H.
Deposit date:2013-06-01
Release date:2014-03-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of Ets1 activation by Runx1.
Leukemia, 28, 2014
2J6W
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BU of 2j6w by Molmil
R164N mutant of the RUNX1 Runt domain
Descriptor: CHLORIDE ION, RUNT-RELATED TRANSCRIPTION FACTOR 1
Authors:Grembecka, J, Zhe, L, Lukasik, S.M, Liu, Y, Bielnicka, I, Bushweller, J.H, Speck, N.A.
Deposit date:2006-10-04
Release date:2007-10-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Mutation in the S-Switch Region of the Runt Domain Alters the Dynamics of an Allosteric Network Responsible for Cbfbeta Regulation.
J.Mol.Biol., 364, 2006
1HJC
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BU of 1hjc by Molmil
CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER
Descriptor: DNA (5'-(*GP*AP*AP*CP*TP*CP*TP*GP*TP*GP*GP* TP*TP*GP*CP*G)-3'), DNA (5'-(CP*CP*GP*CP*AP*AP*CP*CP*AP*CP*AP* GP*AP*GP*TP*T)-3'), RUNT-RELATED TRANSCRIPTION FACTOR 1
Authors:Tahirov, T.H, Ogata, K.
Deposit date:2001-01-11
Release date:2001-03-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Analyses of DNA Recognition by the Aml1/Runx-1 Runt Domain and its Allosteric Control by Cbfbeta
Cell(Cambridge,Mass.), 104, 2001
4L0Z
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BU of 4l0z by Molmil
Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 2)
Descriptor: 5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Protein C-ets-1, ...
Authors:Tahirov, T.H.
Deposit date:2013-06-01
Release date:2014-03-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of Ets1 activation by Runx1.
Leukemia, 28, 2014
3WTY
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BU of 3wty by Molmil
Crystal structure of the complex comprised of ETS1(G333P), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA
Descriptor: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ...
Authors:Shiina, M, Hamada, K, Ogata, K.
Deposit date:2014-04-21
Release date:2014-08-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
3WTV
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BU of 3wtv by Molmil
Crystal structure of the complex comprised of ETS1(V170G), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA
Descriptor: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ...
Authors:Shiina, M, Hamada, K, Ogata, K.
Deposit date:2014-04-21
Release date:2014-08-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
3WTU
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BU of 3wtu by Molmil
Crystal structure of the complex comprised of ETS1 (V170A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA
Descriptor: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ...
Authors:Shiina, M, Hamada, K, Ogata, K.
Deposit date:2014-04-21
Release date:2014-08-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
3WTX
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BU of 3wtx by Molmil
Crystal structure of the complex comprised of ETS1(Y329A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA
Descriptor: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ...
Authors:Shiina, M, Hamada, K, Ogata, K.
Deposit date:2014-04-21
Release date:2014-08-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
3WTW
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BU of 3wtw by Molmil
Crystal structure of the complex comprised of ETS1(K167A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA
Descriptor: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ...
Authors:Shiina, M, Hamada, K, Ogata, K.
Deposit date:2014-04-21
Release date:2014-08-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
1HJB
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BU of 1hjb by Molmil
CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER
Descriptor: CCAAT/ENHANCER BINDING PROTEIN BETA, DNA (5'-(*CP*CP*GP*CP*AP*AP*CP*CP*AP*CP* AP*GP*AP*GP*TP*TP*TP*GP*GP*AP*AP*AP*TP*CP*TP*T)-3'), DNA (5'-(*GP*AP*AP*GP*AP*TP*TP*TP*CP*CP* AP*AP*AP*CP*TP*CP*TP*GP*TP*GP*GP*TP*TP*GP*CP*G)-3'), ...
Authors:Tahirov, T.H, Ogata, K.
Deposit date:2001-01-11
Release date:2001-03-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Analyses of DNA Recognition by the Aml1/Runx-1 Runt Domain and its Allosteric Control by Cbfbeta
Cell(Cambridge,Mass.), 104, 2001
1IO4
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BU of 1io4 by Molmil
CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN-CBFBETA CORE DOMAIN HETERODIMER AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER
Descriptor: CAAT/ENHANCER BINDING PROTEIN BETA, CORE-BINDING FACTOR, BETA SUBUNIT, ...
Authors:Tahirov, T.H, Ogata, K.
Deposit date:2001-01-10
Release date:2001-03-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta.
Cell(Cambridge,Mass.), 104, 2001

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PDB entries from 2024-07-17

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