5ZLT
| Crystal structure of UDP-GlcNAc 2-epimerase NeuC complexed with UDP | Descriptor: | GDP/UDP-N,N'-diacetylbacillosamine 2-epimerase (Hydrolyzing), SULFATE ION, URIDINE-5'-DIPHOSPHATE | Authors: | Ko, T.P, Hsieh, T.J, Yang, C.S, Chen, Y. | Deposit date: | 2018-03-29 | Release date: | 2018-05-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The tetrameric structure of sialic acid-synthesizing UDP-GlcNAc 2-epimerase fromAcinetobacter baumannii: A comparative study with human GNE. J. Biol. Chem., 293, 2018
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4FKZ
| Crystal structure of Bacillus subtilis UDP-GlcNAc 2-epimerase in complex with UDP-GlcNAc and UDP | Descriptor: | UDP-N-acetylglucosamine 2-epimerase, URIDINE-5'-DIPHOSPHATE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | Authors: | Yang, C.S, Chen, S.C, Kuan, S.M, Chen, Y.R, Liu, Y.H, Chen, Y. | Deposit date: | 2012-06-14 | Release date: | 2013-05-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Crystal structure of Bacillus subtilis UDP-GlcNAc 2-epimerase in complex with UDP-GlcNAc and UDP To be Published
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5DLD
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4ZHT
| Crystal structure of UDP-GlcNAc 2-epimerase | Descriptor: | 2-acetamido-2-deoxy-beta-D-mannopyranose, Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, CYTIDINE-5'-MONOPHOSPHATE-5-N-ACETYLNEURAMINIC ACID, ... | Authors: | Chen, S.C, Yang, C.S, Ko, T.P, Chen, Y. | Deposit date: | 2015-04-27 | Release date: | 2016-06-01 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Mechanism and inhibition of human UDP-GlcNAc 2-epimerase, the key enzyme in sialic acid biosynthesis. Sci Rep, 6, 2016
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4HWG
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3OT5
| 2.2 Angstrom Resolution Crystal Structure of putative UDP-N-acetylglucosamine 2-epimerase from Listeria monocytogenes | Descriptor: | DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL, UDP-N-acetylglucosamine 2-epimerase | Authors: | Minasov, G, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-09-10 | Release date: | 2010-09-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | 2.2 Angstrom Resolution Crystal Structure of putative UDP-N-acetylglucosamine 2-epimerase from Listeria monocytogenes. TO BE PUBLISHED
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3BEO
| A Structural Basis for the allosteric regulation of non-hydrolyzing UDP-GlcNAc 2-epimerases | Descriptor: | UDP-N-acetylglucosamine 2-epimerase, URIDINE-5'-DIPHOSPHATE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | Authors: | Velloso, L.M, Bhaskaran, S.S, Schuch, R, Fischetti, V.A, Stebbins, C.E. | Deposit date: | 2007-11-19 | Release date: | 2008-02-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A structural basis for the allosteric regulation of non-hydrolysing UDP-GlcNAc 2-epimerases. Embo Rep., 9, 2008
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1F6D
| THE STRUCTURE OF UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE FROM E. COLI. | Descriptor: | CHLORIDE ION, SODIUM ION, UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE, ... | Authors: | Campbell, R.E, Mosimann, S.C, Tanner, M.E, Strynadka, N.C.J. | Deposit date: | 2000-06-21 | Release date: | 2000-12-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The structure of UDP-N-acetylglucosamine 2-epimerase reveals homology to phosphoglycosyl transferases. Biochemistry, 39, 2000
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5ENZ
| S. aureus MnaA-UDP co-structure | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, TETRAETHYLENE GLYCOL, ... | Authors: | Fischmann, T.O. | Deposit date: | 2015-11-09 | Release date: | 2016-04-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets. Plos Pathog., 12, 2016
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3DZC
| 2.35 Angstrom resolution structure of WecB (VC0917), a UDP-N-acetylglucosamine 2-epimerase from Vibrio cholerae. | Descriptor: | CALCIUM ION, CHLORIDE ION, UDP-N-acetylglucosamine 2-epimerase | Authors: | Minasov, G, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Kwon, K, Hasseman, J, Peterson, S.N, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2008-07-29 | Release date: | 2008-08-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | 2.35 Angstrom resolution structure of WecB (VC0917), a UDP-N-acetylglucosamine 2-epimerase from Vibrio cholerae. TO BE PUBLISHED
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1O6C
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8AHE
| PAC-FragmentDEL: Photoactivated covalent capture of DNA encoded fragments for hit discovery | Descriptor: | SULFATE ION, UDP-N-acetylglucosamine 2-epimerase, ~{N},5-dimethyl-1-phenyl-pyrazole-4-sulfonamide | Authors: | Baker, L.M, Murray, J.B, Hubbard, R.E. | Deposit date: | 2022-07-21 | Release date: | 2022-09-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.108 Å) | Cite: | PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery. Rsc Med Chem, 13, 2022
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8AHF
| PAC-FragmentDEL: Photoactivated covalent capture of DNA encoded fragments for hit discovery | Descriptor: | (2~{R},4~{S})-4-[bis(fluoranyl)methoxy]-~{N}-methyl-1-(2~{H}-pyrazolo[4,3-b]pyridin-6-ylcarbonyl)pyrrolidine-2-carboxamide, SULFATE ION, UDP-N-acetylglucosamine 2-epimerase | Authors: | Baker, L.M, Murray, J.B, Hubbard, R.E. | Deposit date: | 2022-07-21 | Release date: | 2022-09-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.271 Å) | Cite: | PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery. Rsc Med Chem, 13, 2022
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1VGV
| Crystal structure of UDP-N-acetylglucosamine_2 epimerase | Descriptor: | UDP-N-acetylglucosamine 2-epimerase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | Authors: | Structural GenomiX | Deposit date: | 2003-11-03 | Release date: | 2003-11-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Structural analysis of a set of proteins resulting from a bacterial genomics project Proteins, 60, 2005
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6VLB
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4NEQ
| The structure of UDP-GlcNAc 2-epimerase from Methanocaldococcus jannaschii | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, UDP-N-acetylglucosamine 2-epimerase | Authors: | Chen, S.C, Yang, C.S, Huang, C.H, Chen, Y. | Deposit date: | 2013-10-29 | Release date: | 2014-04-23 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal structures of the archaeal UDP-GlcNAc 2-epimerase from Methanocaldococcus jannaschii reveal a conformational change induced by UDP-GlcNAc. Proteins, 82, 2014
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5XVS
| Crystal structure of UDP-GlcNAc 2-epimerase NeuC complexed with UDP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GDP/UDP-N,N'-diacetylbacillosamine 2-epimerase (Hydrolyzing), LITHIUM ION, ... | Authors: | Ko, T.P, Hsieh, T.J, Chen, S.C, Wu, S.C, Guan, H.H, Yang, C.H, Chen, C.J, Chen, Y. | Deposit date: | 2017-06-28 | Release date: | 2018-04-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.383 Å) | Cite: | The tetrameric structure of sialic acid-synthesizing UDP-GlcNAc 2-epimerase fromAcinetobacter baumannii: A comparative study with human GNE. J. Biol. Chem., 293, 2018
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6VLC
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1V4V
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4NES
| Crystal structure of Methanocaldococcus jannaschii UDP-GlcNAc 2-epimerase in complex with UDP-GlcNAc and UDP | Descriptor: | UDP-N-acetylglucosamine 2-epimerase, URIDINE-5'-DIPHOSPHATE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | Authors: | Chen, S.C, Yang, C.S, Huang, C.H, Chen, Y. | Deposit date: | 2013-10-30 | Release date: | 2014-04-23 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Crystal structures of the archaeal UDP-GlcNAc 2-epimerase from Methanocaldococcus jannaschii reveal a conformational change induced by UDP-GlcNAc. Proteins, 82, 2014
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5ZLR
| Structure of NeuC | Descriptor: | GDP/UDP-N,N'-diacetylbacillosamine 2-epimerase (Hydrolyzing), LITHIUM ION, SULFATE ION | Authors: | Ko, T.P, Hsieh, T.J, Yang, C.S, Chen, Y. | Deposit date: | 2018-03-29 | Release date: | 2018-05-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | The tetrameric structure of sialic acid-synthesizing UDP-GlcNAc 2-epimerase fromAcinetobacter baumannii: A comparative study with human GNE. J. Biol. Chem., 293, 2018
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7YA2
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7VYY
| The crystal structure of Non-hydrolyzing UDPGlcNAc 2-epimerase | Descriptor: | Putative UDP-N-acetylglucosamine 2-epimerase, SODIUM ION | Authors: | Li, T.L, Rattinam, R. | Deposit date: | 2021-11-15 | Release date: | 2022-11-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.443 Å) | Cite: | KasQ an Epimerase Primes the Biosynthesis of Aminoglycoside Antibiotic Kasugamycin and KasF/H Acetyltransferases Inactivate Its Activity. Biomedicines, 10, 2022
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7VZA
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7VZ6
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