7DC1
 
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3K7R
 | | Crystal structure of [TM][CuAtx1]3 | | Descriptor: | COPPER (II) ION, D-MALATE, Metal homeostasis factor ATX1, ... | | Authors: | Xue, Y, Alvarez, H.M, Robinson, C.D, Mondragon, A, O'Halloran, T.V. | | Deposit date: | 2009-10-13 | | Release date: | 2009-11-24 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Tetrathiomolybdate inhibits copper trafficking proteins through metal cluster formation.
Science, 327, 2010
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1Q8L
 | | Second Metal Binding Domain of the Menkes ATPase | | Descriptor: | Copper-transporting ATPase 1 | | Authors: | Jones, C.E, Daly, N.L, Cobine, P.A, Craik, D.J, Dameron, C.T. | | Deposit date: | 2003-08-21 | | Release date: | 2004-01-20 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure and metal binding studies of the second copper binding domain of the Menkes ATPase.
J.Struct.Biol., 143, 2003
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5F0W
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4QOT
 | | Crystal structure of human copper chaperone bound to the platinum ion | | Descriptor: | Copper transport protein ATOX1, PLATINUM (II) ION, SULFATE ION | | Authors: | Belviso, B.D, Galliani, A, Caliandro, R, Arnesano, F, Natile, G. | | Deposit date: | 2014-06-20 | | Release date: | 2015-06-24 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Oxaliplatin Binding to Human Copper Chaperone Atox1 and Protein Dimerization
Inorg.Chem., 55, 2016
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3CJK
 | | Crystal structure of the adduct HAH1-Cd(II)-MNK1. | | Descriptor: | CADMIUM ION, Copper transport protein ATOX1, Copper-transporting ATPase 1 | | Authors: | Banci, L, Bertini, I, Calderone, V, Felli, I, Della-Malva, N, Pavelkova, A, Rosato, A. | | Deposit date: | 2008-03-13 | | Release date: | 2008-12-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Copper(I)-mediated protein-protein interactions result from suboptimal interaction surfaces.
Biochem.J., 422, 2009
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3DXS
 | | Crystal structure of a copper binding domain from HMA7, a P-type ATPase | | Descriptor: | Copper-transporting ATPase RAN1, LITHIUM ION, ZINC ION | | Authors: | Zimmermann, M, Xiao, Z, Clarke, O.B, Gulbis, J.M, Wedd, A.G. | | Deposit date: | 2008-07-25 | | Release date: | 2009-08-11 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Metal binding affinities of Arabidopsis zinc and copper transporters: selectivities match the relative, but not the absolute, affinities of their amino-terminal domains.
Biochemistry, 48, 2009
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5T7L
 | | Pt(II)-mediated copper-dependent interactions between ATOX1 and MNK1 | | Descriptor: | COPPER (II) ION, Copper transport protein ATOX1, Copper-transporting ATPase 1, ... | | Authors: | Caliandro, R, Mirabelli, V, Caliandro, R, Rosato, A, Lasorsa, A, Galliani, A, Arnesano, F, Natile, G. | | Deposit date: | 2016-09-05 | | Release date: | 2016-10-12 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.83 Å) | | Cite: | Mechanistic and Structural Basis for Inhibition of Copper Trafficking by Platinum Anticancer Drugs.
J.Am.Chem.Soc., 141, 2019
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6FF1
 | | CsoZ metallochaperone | | Descriptor: | CALCIUM ION, CsoZ | | Authors: | Pelicioli-Riboldi, G, Basle, A, Waldron, K. | | Deposit date: | 2018-01-03 | | Release date: | 2019-01-30 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | The copper homeostasis system of Staphylococcus aureus:
Two putative metallochaperones with contrasting copper binding properties.
To Be Published
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6FF2
 | | CopZ metallochaperone | | Descriptor: | COPPER (I) ION, Copper chaperone CopZ, MAGNESIUM ION | | Authors: | Pelicioli-Riboldi, G, Basle, A, Waldron, K. | | Deposit date: | 2018-01-03 | | Release date: | 2019-01-30 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | The copper homeostasis system of Staphylococcus aureus:
Two putative metallochaperones with contrasting copper binding properties.
To Be Published
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5VDF
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5ZCZ
 | | Solution structure of the T. Thermophilus HB8 TTHA1718 protein in living eukaryotic cells by in-cell NMR spectroscopy | | Descriptor: | Heavy metal binding protein | | Authors: | Tanaka, T, Teppei, I, Kamoshida, H, Mishima, M, Shirakawa, M, Guentert, P, Ito, Y. | | Deposit date: | 2018-02-22 | | Release date: | 2019-08-21 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | High-Resolution Protein 3D Structure Determination in Living Eukaryotic Cells.
Angew.Chem.Int.Ed.Engl., 58, 2019
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6A72
 | | Copper transporter protein | | Descriptor: | ATP7B protein, CALCIUM ION, dioxo(di-mu-sulfide)dimolybdenum | | Authors: | Chen, W.B. | | Deposit date: | 2018-07-01 | | Release date: | 2019-04-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein.
Nat Commun, 10, 2019
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6A71
 | | Crystal Structure of Human ATP7B and TM Complex | | Descriptor: | ATP7B protein, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Chen, W.B. | | Deposit date: | 2018-06-30 | | Release date: | 2019-04-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein.
Nat Commun, 10, 2019
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5VDE
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2CRL
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4A48
 | | Crosstalk between Cu(I) and Zn(II) homeostasis | | Descriptor: | MAGNESIUM ION, PROBABLE COPPER-TRANSPORTING ATPASE PACS, ZINC ION | | Authors: | Badarau, A, Basle, A, Firbank, S.J, Denninson, C. | | Deposit date: | 2011-10-07 | | Release date: | 2012-12-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Investigating the Role of Zinc and Copper Binding Motifs of Trafficking Sites in the Cyanobacterium Synechocystis Pcc 6803.
Biochemistry, 52, 2013
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4A46
 | | Crosstalk between Cu(I) and Zn(II) homeostasis | | Descriptor: | CHLORIDE ION, SODIUM ION, SSR2857 PROTEIN, ... | | Authors: | Badarau, A, Basle, A, Firbank, S.J, Denninson, C. | | Deposit date: | 2011-10-07 | | Release date: | 2012-12-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crosstalk between Cu(I) and Zn(II) Homeostasis Via Atx1 and Cognate Domains.
Chem.Commun.(Camb.), 49, 2013
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4A4J
 | | Crosstalk between Cu(I) and Zn(II) homeostasis | | Descriptor: | COPPER-TRANSPORTING ATPASE PACS, ZINC ION | | Authors: | Badarau, A, Basle, A, Firbank, S.J, Denninson, C. | | Deposit date: | 2011-10-14 | | Release date: | 2012-12-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Investigating the Role of Zinc and Copper Binding Motifs of Trafficking Sites in the Cyanobacterium Synechocystis Pcc 6803.
Biochemistry, 52, 2013
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4A47
 | | Crosstalk between Cu(I) and Zn(II) homeostasis | | Descriptor: | SSR2857 PROTEIN, ZINC ION | | Authors: | Badarau, A, Basle, A, Firbank, S.J, Denninson, C. | | Deposit date: | 2011-10-07 | | Release date: | 2012-12-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Investigating the Role of Zinc and Copper Binding Motifs of Trafficking Sites in the Cyanobacterium Synechocystis Pcc 6803.
Biochemistry, 52, 2013
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3I9Z
 | | Crystal structure of a metallochaperone with a trinuclear Cu(I) cluster | | Descriptor: | COPPER (I) ION, Copper chaperone copZ | | Authors: | Hearnshaw, S.J, Zhou, L, Le Brun, N.E, Hemmings, A.M. | | Deposit date: | 2009-07-13 | | Release date: | 2009-11-17 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Mechanistic insights into Cu(I) cluster transfer between the chaperone CopZ and its cognate Cu(I)-transporting P-type ATPase, CopA.
Biochem.J., 424, 2009
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3IWX
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2AW0
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3IWL
 | | Crystal structure of cisplatin bound to a human copper chaperone (monomer) | | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, Copper transport protein ATOX1, PLATINUM (II) ION, ... | | Authors: | Boal, A.K, Rosenzweig, A.C. | | Deposit date: | 2009-09-02 | | Release date: | 2009-09-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structures of cisplatin bound to a human copper chaperone.
J.Am.Chem.Soc., 131, 2009
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2AJ1
 | | Solution structure of apoCadA | | Descriptor: | Probable cadmium-transporting ATPase | | Authors: | Banci, L, Bertini, I, Ciofi-Baffoni, S, Su, X.-C, Miras, R, Bal, N, Mintz, E, Catty, P, Shokes, J.E, Scott, R.A. | | Deposit date: | 2005-08-01 | | Release date: | 2006-05-02 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structural basis for metal binding specificity: the N-terminal cadmium binding domain of the P1-type ATPase CadA
J.Mol.Biol., 356, 2006
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