4QOT

Crystal structure of human copper chaperone bound to the platinum ion

Summary for 4QOT

Related3IWX 3IWL
DescriptorCopper transport protein ATOX1, PLATINUM (II) ION, SULFATE ION, ... (4 entities in total)
Functional Keywordsmetal-binding, metal transport, chaperone, platinum, oxaliplatin
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight15695.76
Authors
Belviso, B.D.,Galliani, A.,Caliandro, R.,Arnesano, F.,Natile, G. (deposition date: 2014-06-20, release date: 2015-06-24, Last modification date: 2016-10-26)
Primary citation
Belviso, B.D.,Galliani, A.,Lasorsa, A.,Mirabelli, V.,Caliandro, R.,Arnesano, F.,Natile, G.
Oxaliplatin Binding to Human Copper Chaperone Atox1 and Protein Dimerization
Inorg.Chem., 55:6563-6573, 2016
PubMed: 27305454 (PDB entries with the same primary citation)
DOI: 10.1021/acs.inorgchem.6b00750
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.245202.6%1.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload