8X1N
| Cryo-EM structure of human alpha-fetoprotein | Descriptor: | Alpha-fetoprotein, PALMITIC ACID, ZINC ION, ... | Authors: | Liu, Z.M, Li, M.S, Wu, C, Liu, K. | Deposit date: | 2023-11-08 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.31 Å) | Cite: | Structural characteristics of alpha-fetoprotein, including N-glycosylation, metal ion and fatty acid binding sites. Commun Biol, 7, 2024
|
|
4S1Y
| |
3CX9
| Crystal Structure of Human serum albumin complexed with Myristic acid and lysophosphatidylethanolamine | Descriptor: | (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, MYRISTIC ACID, Serum albumin | Authors: | Guo, S, Yang, F, Chen, L, Bian, C, Huang, M. | Deposit date: | 2008-04-24 | Release date: | 2009-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of transport of lysophospholipids by human serum albumin. Biochem.J., 423, 2009
|
|
6CI6
| Crystal structure of equine serum albumin in complex with nabumetone | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, Serum albumin, ... | Authors: | Venkataramany, B.S, Czub, M.P, Shabalin, I.G, Handing, K.B, Steen, E.H, Cooper, D.R, Joachimiak, A, Satchell, K.J.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2018-02-23 | Release date: | 2018-03-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Albumin-Based Transport of Nonsteroidal Anti-Inflammatory Drugs in Mammalian Blood Plasma. J.Med.Chem., 2020
|
|
7Q4X
| |
7JWN
| Crystal structure of Human Serum Albumin in complex with ketoprofen | Descriptor: | (2S)-2-[3-(benzenecarbonyl)phenyl]propanoic acid, (R)-Ketoprofen, 1,2-ETHANEDIOL, ... | Authors: | Czub, M.P, Shabalin, I.G, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-08-25 | Release date: | 2020-09-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Organism-specific differences in the binding of ketoprofen to serum albumin. Iucrj, 9, 2022
|
|
1O9X
| HUMAN SERUM ALBUMIN COMPLEXED WITH TETRADECANOIC ACID (MYRISTIC ACID) AND HEMIN | Descriptor: | MYRISTIC ACID, PROTOPORPHYRIN IX CONTAINING FE, SERUM ALBUMIN | Authors: | Zunszain, P.A, Ghuman, J, Komatsu, T, Tsuchida, E, Curry, S. | Deposit date: | 2002-12-20 | Release date: | 2003-03-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal Structure Analysis of Human Serum Albumin Complexed with Hemin and Fatty Acid Bmc Struct.Biol., 3, 2003
|
|
7QFE
| Crystal structure of Human Serum albumin in complex with Gemfibrozil | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid, MYRISTIC ACID, ... | Authors: | Liberi, S, Moro, G, Angelini, A, Cendron, L. | Deposit date: | 2021-12-05 | Release date: | 2022-03-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Analysis of Human Serum Albumin in Complex with the Fibrate Drug Gemfibrozil. Int J Mol Sci, 23, 2022
|
|
1UOR
| |
2I30
| Human serum albumin complexed with myristate and salicylic acid | Descriptor: | 2-HYDROXYBENZOIC ACID, MYRISTIC ACID, Serum albumin | Authors: | Yang, F, Bian, C, Zhu, L, Zhao, G, Huang, Z, Huang, M. | Deposit date: | 2006-08-17 | Release date: | 2006-12-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Effect of human serum albumin on drug metabolism: Structural evidence of esterase activity of human serum albumin J.Struct.Biol., 157, 2007
|
|
2I2Z
| Human serum albumin complexed with myristate and aspirin | Descriptor: | 2-HYDROXYBENZOIC ACID, MYRISTIC ACID, Serum albumin | Authors: | Yang, F, Bian, C, Zhu, L, Zhao, G, Huang, Z, Huang, M. | Deposit date: | 2006-08-17 | Release date: | 2006-12-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Effect of human serum albumin on drug metabolism: Structural evidence of esterase activity of human serum albumin J.Struct.Biol., 157, 2007
|
|
7MBL
| Crystal structure of Equine Serum Albumin in complex with Cobalt (II) | Descriptor: | COBALT (II) ION, SULFATE ION, Serum albumin | Authors: | Shabalin, I.G, Czub, M.P, Handing, K.B, Cymborowski, M.T, Grabowski, M, Cooper, D.R, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-03-31 | Release date: | 2021-04-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of Equine Serum Albumin in complex with Cobalt To Be Published
|
|
1YSX
| Solution structure of domain 3 from human serum albumin complexed to an anti-apoptotic ligand directed against Bcl-xL and Bcl-2 | Descriptor: | 4-({2-[(2,4-DIMETHYLPHENYL)SULFANYL]ETHYL}AMINO)-N-[(4'-FLUORO-1,1'-BIPHENYL-4-YL)CARBONYL]-3-NITROBENZENESULFONAMIDE, Serum albumin | Authors: | Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H. | Deposit date: | 2005-02-09 | Release date: | 2005-06-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | An inhibitor of Bcl-2 family proteins induces regression of solid tumours Nature, 435, 2005
|
|
5UJB
| Structure of a Mcl-1 Inhibitor Binding to Site 3 of Human Serum Albumin | Descriptor: | 4-{8-chloro-11-[3-(4-chloro-3,5-dimethylphenoxy)propyl]-1-oxo-7-(1,3,5-trimethyl-1H-pyrazol-4-yl)-4,5-dihydro-1H-[1,4]diazepino[1,2-a]indol-2(3H)-yl}-1-methyl-1H-indole-6-carboxylic acid, PHOSPHATE ION, Serum albumin | Authors: | Zhao, B. | Deposit date: | 2017-01-17 | Release date: | 2017-05-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of a Myeloid cell leukemia-1 (Mcl-1) inhibitor bound to drug site 3 of Human Serum Albumin. Bioorg. Med. Chem., 25, 2017
|
|
5V0V
| Crystal structure of Equine Serum Albumin complex with etodolac | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, Serum albumin, ... | Authors: | Czub, M.P, Shabalin, I.G, Handing, K.B, Venkataramany, B.S, Steen, E.H, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-02-28 | Release date: | 2017-03-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Albumin-Based Transport of Nonsteroidal Anti-Inflammatory Drugs in Mammalian Blood Plasma. J.Med.Chem., 2020
|
|
5IJE
| Crystal structure of Equine Serum Albumin in the presence of 30 mM zinc at pH 7.4 | Descriptor: | SULFATE ION, Serum albumin, ZINC ION | Authors: | Handing, K.B, Shabalin, I.G, Cooper, D.R, Szlachta, K, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2016-03-01 | Release date: | 2016-04-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins. Chem Sci, 7, 2016
|
|
5IIX
| Crystal structure of Equine Serum Albumin in the presence of 15 mM zinc at pH 6.5 | Descriptor: | SULFATE ION, Serum albumin, UNKNOWN LIGAND, ... | Authors: | Handing, K.B, Shabalin, I.G, Cooper, D.R, Gasiorowska, O.A, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2016-03-01 | Release date: | 2016-03-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins. Chem Sci, 7, 2016
|
|
5IJ5
| Crystal structure of Equine Serum Albumin in the presence of 50 mM zinc at pH 4.5 | Descriptor: | GLYCEROL, Serum albumin, ZINC ION | Authors: | Handing, K.B, Majorek, K.A, Shabalin, I.G, Cymborowski, M.T, Zheng, H, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2016-03-01 | Release date: | 2016-03-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins. Chem Sci, 7, 2016
|
|
7Z57
| Crystal structure of Human Serum Albumin in complex with surfactant GenX (2,3,3,3-tetrafluoro-2-(heptafluoropropoxy) propanoate) | Descriptor: | (2R)-2,3,3,3-tetrakis(fluoranyl)-2-[1,1,2,2,3,3,3-heptakis(fluoranyl)propoxy]propanoic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, Albumin, ... | Authors: | Liberi, S, Moro, G, Vascon, F, Linciano, S, De Toni, L, Angelin, A, Cendron, L. | Deposit date: | 2022-03-08 | Release date: | 2022-10-12 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Investigation of the Interaction between Human Serum Albumin and Branched Short-Chain Perfluoroalkyl Compounds. Chem.Res.Toxicol., 35, 2022
|
|
8J8E
| Human serum albumin-palladium(II) agent complex | Descriptor: | PALMITIC ACID, Serum albumin, ~{N},~{N}-dimethyl-7-phenyl-3-thia-1$l^{4},5,6$l^{4}-triaza-2$l^{3}-palladatricyclo[6.4.0.0^{2,6}]dodeca-1(12),4,6,8,10-pentaen-4-amine | Authors: | Zhang, Z.L, Zhang, J.Z. | Deposit date: | 2023-05-01 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of human serum albumin palladium(II) agent complex To Be Published
|
|
8OI2
| Crystal structure of Alb1 megabody in complex with human serum albumin | Descriptor: | Alb1 Megabody, Albumin | Authors: | De Felice, S, Zoia, G, Romanyuk, Z, Pardon, E, Steyaert, J, Angelini, A, Cendron, L. | Deposit date: | 2023-03-22 | Release date: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal structure of human serum albumin in complex with megabody reveals unique human and murine cross-reactive binding site. Protein Sci., 33, 2024
|
|
8A9Q
| Computational design of stable mammalian serum albumins for bacterial expression | Descriptor: | Albumin, LAURIC ACID, MYRISTIC ACID, ... | Authors: | Khersonsky, O, Dym, O, Fleishman, J.S. | Deposit date: | 2022-06-29 | Release date: | 2023-05-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Stable Mammalian Serum Albumins Designed for Bacterial Expression. J.Mol.Biol., 435, 2023
|
|
8Q3F
| |
7OV5
| Structure of Human Serum Albumin in complex with Aristolochic Acid II at 1.9 A resolution | Descriptor: | 1,2-ETHANEDIOL, 6-nitronaphtho[1,2-e][1,3]benzodioxole-5-carboxylic acid, MYRISTIC ACID, ... | Authors: | Pomyalov, S, Sidorenko, V.S, Grollman, A.P, Shoham, G. | Deposit date: | 2021-06-14 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and mechanistic insights for the binding of aristolochic acids and their active metabolites to
human serum albumin To Be Published
|
|
7OV6
| Structure of Human Serum Albumin in complex with Aristolochic Acid I at 1.9 A resolution - Optimized | Descriptor: | 1,2-ETHANEDIOL, 8-methoxy-6-nitro-naphtho[1,2-e][1,3]benzodioxole-5-carboxylic acid, MYRISTIC ACID, ... | Authors: | Pomyalov, S, Sidorenko, V.S, Grollman, A.P, Shoham, G. | Deposit date: | 2021-06-14 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and mechanistic insights for the binding of aristolochic acids and their active metabolites to human serum albumin To Be Published
|
|