7RDE
 
 | | Human Triose Phosphate Isomerase Q181P | | Descriptor: | BROMIDE ION, CALCIUM ION, Triosephosphate isomerase | | Authors: | VanDemark, A.P, Kowalski, J. | | Deposit date: | 2021-07-09 | | Release date: | 2022-05-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.31 Å) | | Cite: | Itavastatin and resveratrol increase triosephosphate isomerase protein in a newly identified variant of TPI deficiency.
Dis Model Mech, 15, 2022
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4UNL
 | | Crystal structure of a single mutant (N71D) of triosephosphate isomerase from human | | Descriptor: | TRIOSEPHOSPHATE ISOMERASE | | Authors: | DeLaMora-DeLaMora, I, Torres-Larios, A, Enriquez-Flores, S, Mendez, S.T, Castillo-Villanueva, A, Gomez-Manzo, S, Lopez-Velazquez, G, Marcial-Quino, J, Torres-Arroyo, A, Garcia-Torres, I, Reyes-Vivas, H, Oria-Hernandez, J. | | Deposit date: | 2014-05-29 | | Release date: | 2015-02-04 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal Structure of a Single Mutant (N71D) of Triosephosphate Isomerase from Human
To be Published
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4POC
 | | Structure of Triosephosphate Isomerase Wild Type human enzyme. | | Descriptor: | BROMIDE ION, PHOSPHATE ION, POTASSIUM ION, ... | | Authors: | Amrich, C.G, Aslam, A.A, Heroux, A, VanDemark, A.P. | | Deposit date: | 2014-02-25 | | Release date: | 2015-01-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.601 Å) | | Cite: | Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim.Biophys.Acta, 1852, 2015
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6UPF
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4ZVJ
 | | Structure of human triose phosphate isomerase K13M | | Descriptor: | POTASSIUM ION, SODIUM ION, Triosephosphate isomerase | | Authors: | Amrich, C.G, Smith, C, Heroux, A, VanDemark, A.P. | | Deposit date: | 2015-05-18 | | Release date: | 2016-03-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.6996 Å) | | Cite: | Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim. Biophys. Acta, 1852, 2015
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2JK2
 | | STRUCTURAL BASIS OF HUMAN TRIOSEPHOSPHATE ISOMERASE DEFICIENCY. CRYSTAL STRUCTURE OF THE WILD TYPE ENZYME. | | Descriptor: | TRIOSEPHOSPHATE ISOMERASE | | Authors: | Rodriguez-Almazan, C, Arreola-Alemon, R, Rodriguez-Larrea, D, Aguirre-Lopez, B, De Gomez-Puyou, M.T, Perez-Montfort, R, Costas, M, Gomez-Puyou, A, Torres-Larios, A. | | Deposit date: | 2008-06-22 | | Release date: | 2008-07-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural Basis of Human Triosephosphate Isomerase Deficiency: Mutation E104D is Related to Alterations of a Conserved Water Network at the Dimer Interface.
J.Biol.Chem., 283, 2008
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6UP1
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2VOM
 | | Structural basis of human triosephosphate isomerase deficiency. Mutation E104D and correlation to solvent perturbation. | | Descriptor: | TRIOSEPHOSPHATE ISOMERASE | | Authors: | Rodriguez-Almazan, C, Arreola-Alemon, R, Rodriguez-Larrea, D, Aguirre-Lopez, B, de Gomez-Puyou, M.T, Perez-Montfort, R, Costas, M, Gomez-Puyou, A, Torres-Larios, A. | | Deposit date: | 2008-02-19 | | Release date: | 2008-06-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural Basis of Human Triosephosphate Isomerase Deficiency: Mutation E104D is Related to Alterations of a Conserved Water Network at the Dimer Interface.
J.Biol.Chem., 283, 2008
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4BR1
 | | Protease-induced heterodimer of human triosephosphate isomerase. | | Descriptor: | TRIOSEPHOSPHATE ISOMERASE | | Authors: | DeLaMora-DeLaMora, I, Torres-Larios, A, Hernandez-Alcantara, G, Mendoza-Hernandez, G, Enriquez-Flores, S, Mendez, S.T, Castillo-Villanueva, A, Garcia-Torres, I, Torres-Arroyo, A, Gomez-Manzo, S, Marcial-Quino, J, Oria-Hernandez, J, Lopez-Velazquez, G, Reyes-Vivas, H. | | Deposit date: | 2013-06-03 | | Release date: | 2013-06-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Differential Proteolysis in Human Triosephosphate Isomerase
To be Published
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6UP5
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1KLU
 | | Crystal structure of HLA-DR1/TPI(23-37) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2) | | Descriptor: | ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ... | | Authors: | Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A. | | Deposit date: | 2001-12-12 | | Release date: | 2002-08-02 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.
J.Mol.Biol., 319, 2002
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4POD
 | | Structure of Triosephosphate Isomerase I170V mutant human enzyme. | | Descriptor: | BROMIDE ION, PHOSPHATE ION, POTASSIUM ION, ... | | Authors: | Amrich, C.G, Aslam, A.A, Heroux, A, VanDemark, A.P. | | Deposit date: | 2014-02-25 | | Release date: | 2015-01-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim.Biophys.Acta, 1852, 2015
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7T0Q
 | | human triosephosphate isomerase mutant v154m | | Descriptor: | 2-PHOSPHOGLYCOLIC ACID, GLYCEROL, ISOPROPYL ALCOHOL, ... | | Authors: | Romero, J.M. | | Deposit date: | 2021-11-30 | | Release date: | 2022-12-14 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | human triosephosphate isomerase mutant v154m
To Be Published
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7UXB
 | | Human triosephosphate isomerase mutant G122R | | Descriptor: | GLYCEROL, ISOPROPYL ALCOHOL, Triosephosphate isomerase | | Authors: | Romero, J.M. | | Deposit date: | 2022-05-05 | | Release date: | 2023-05-24 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Human triosephosphate isomerase mutant G122R
To Be Published
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6UP8
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4UNK
 | | Crystal structure of human triosephosphate isomerase (mutant N15D) | | Descriptor: | TRIOSEPHOSPHATE ISOMERASE | | Authors: | DeLaMora-DeLaMora, I, Torres-Larios, A, Enriquez-Flores, S, Mendez, S.T, Castillo-Villanueva, A, Gomez-Manzo, S, Lopez-Velazquez, G, Marcial-Quino, J, Torres-Arroyo, A, Garcia-Torres, I, Reyes-Vivas, H, Oria-Hernandez, J. | | Deposit date: | 2014-05-29 | | Release date: | 2015-02-04 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of Human Triosephosphate Isomerase (Mutant N15D)
To be Published
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6D43
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7UXV
 | | human triosephosphate isomerase mutant G122R | | Descriptor: | 2-PHOSPHOGLYCOLIC ACID, GLYCEROL, ISOPROPYL ALCOHOL, ... | | Authors: | Romero, J.M. | | Deposit date: | 2022-05-06 | | Release date: | 2023-05-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | human triosephosphate isomerase mutant G122R
To Be Published
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6NLH
 | | Structure of human triose phosphate isomerase R189A | | Descriptor: | BROMIDE ION, PHOSPHATE ION, SODIUM ION, ... | | Authors: | Richards, K.R, Roland, B.P, Palladino, M.J, VanDemark, A.P. | | Deposit date: | 2019-01-08 | | Release date: | 2019-06-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.199 Å) | | Cite: | Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo.
Biochim Biophys Acta Mol Basis Dis, 1865, 2019
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1WYI
 | | human triosephosphate isomerase of new crystal form | | Descriptor: | Triosephosphate isomerase | | Authors: | Kinoshita, T. | | Deposit date: | 2005-02-14 | | Release date: | 2005-04-12 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of a high-resolution crystal form of human triosephosphate isomerase: improvement of crystals using the gel-tube method.
Acta Crystallogr.,Sect.F, 61, 2005
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7SX1
 | | human triosephosphate isomerase mutant v154m | | Descriptor: | ISOPROPYL ALCOHOL, Triosephosphate isomerase | | Authors: | Romero, J.M. | | Deposit date: | 2021-11-22 | | Release date: | 2022-11-30 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | human triosephosphate isomerase mutant v154m
To Be Published
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6C2G
 | | Human triosephosphate isomerase mutant V231M | | Descriptor: | Triosephosphate isomerase | | Authors: | Torres, L.A, Enriquez, F.S. | | Deposit date: | 2018-01-08 | | Release date: | 2018-03-21 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Differential effects on enzyme stability and kinetic parameters of mutants related to human triosephosphate isomerase deficiency.
Biochim. Biophys. Acta, 1862, 2018
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1KLG
 | | Crystal structure of HLA-DR1/TPI(23-37, Thr28-->Ile mutant) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2) | | Descriptor: | ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ... | | Authors: | Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A. | | Deposit date: | 2001-12-11 | | Release date: | 2002-08-02 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.
J.Mol.Biol., 319, 2002
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4E41
 | | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4 | | Descriptor: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ... | | Authors: | Deng, L, Langley, R.J, Wang, Q, Topalian, S.L, Mariuzza, R.A. | | Deposit date: | 2012-03-11 | | Release date: | 2012-08-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Proc.Natl.Acad.Sci.USA, 2012
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1HTI
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