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PDB: 8 results

1N3L
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BU of 1n3l by Molmil
Crystal structure of a human aminoacyl-tRNA synthetase cytokine
Descriptor: GLYCEROL, SULFATE ION, tyrosyl-tRNA synthetase
Authors:Yang, X.-L, Skene, R.J, McRee, D.E, Schimmel, P.
Deposit date:2002-10-28
Release date:2002-11-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Crystal structure of a human aminoacyl-tRNA synthetase cytokine
Proc.Natl.Acad.Sci.USA, 99, 2002
5THL
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BU of 5thl by Molmil
Crystal structure of the human tyrosyl-tRNA synthetase mutant G41R
Descriptor: Tyrosine--tRNA ligase, cytoplasmic
Authors:Blocquel, D, Sajish, M, Yang, X.L.
Deposit date:2016-09-29
Release date:2017-06-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy.
Nucleic Acids Res., 45, 2017
1Q11
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BU of 1q11 by Molmil
Crystal structure of an active fragment of human tyrosyl-tRNA synthetase with tyrosinol
Descriptor: 4-[(2S)-2-amino-3-hydroxypropyl]phenol, GLYCEROL, PHOSPHATE ION, ...
Authors:Yang, X.-L, Schimmel, P, Ribas de Pouplana, L.
Deposit date:2003-07-18
Release date:2004-01-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains
Proc.Natl.Acad.Sci.USA, 100, 2003
7ROU
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BU of 7rou by Molmil
Structure of human tyrosyl tRNA synthetase in complex with ML901-Tyr
Descriptor: SULFATE ION, Tyrosine--tRNA ligase, cytoplasmic, ...
Authors:Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W.
Deposit date:2021-08-02
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy.
Science, 376, 2022
5THH
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BU of 5thh by Molmil
Crystal structure of a human tyrosyl-tRNA synthetase mutant
Descriptor: TYROSINE, Tyrosine--tRNA ligase, cytoplasmic
Authors:Blocquel, D, Yang, X.L.
Deposit date:2016-09-29
Release date:2017-05-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.959 Å)
Cite:Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy.
Nucleic Acids Res., 45, 2017
4QBT
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BU of 4qbt by Molmil
Crystal structure of tyrosine bound human tyrosyl tRNA synthetase
Descriptor: GLYCEROL, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Mathew, S, Schimmel, P.
Deposit date:2014-05-08
Release date:2014-12-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol.
Nature, 519, 2014
4Q93
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BU of 4q93 by Molmil
Crystal structure of resveratrol bound human tyrosyl tRNA synthetase
Descriptor: CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ...
Authors:Mathew, S, Schimmel, P.
Deposit date:2014-04-28
Release date:2014-12-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol.
Nature, 519, 2014
1NTG
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BU of 1ntg by Molmil
Crystal Structure of the EMAP II-like Cytokine Released from human tyrosyl-tRNA Synthetase
Descriptor: Tyrosyl-tRNA synthetase
Authors:Yang, X.-L, Skene, R.J, Mcree, D.E, Schimmel, P.
Deposit date:2003-01-29
Release date:2003-05-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal Structure of an EMAP-II-like Cytokine Released from a human tRNA Synthetase
Helv.Chim.Acta, 86, 2003

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