7XV0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xv0 by Molmil](/molmil-images/mine/7xv0) | Crystal structure of RPA70N-BLMp1 fusion | Descriptor: | Bloom syndrome protein, Replication protein A 70 kDa DNA-binding subunit | Authors: | Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C. | Deposit date: | 2022-05-20 | Release date: | 2023-06-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural characterization of human RPA70N association with DNA damage response proteins. Elife, 12, 2023
|
|
7AUC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7auc by Molmil](/molmil-images/mine/7auc) | |
7XUW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xuw by Molmil](/molmil-images/mine/7xuw) | Crystal structure of RPA70N-BLMp2 fusion | Descriptor: | fusion protein of Replication protein A 70 kDa DNA-binding subunit and Bloom syndrome protein | Authors: | Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C. | Deposit date: | 2022-05-20 | Release date: | 2023-06-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural characterization of human RPA70N association with DNA damage response proteins. Elife, 12, 2023
|
|
5LUP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lup by Molmil](/molmil-images/mine/5lup) | Structures of DHBN domain of human BLM helicase | Descriptor: | BLM protein, PHOSPHATE ION, POTASSIUM ION | Authors: | Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G. | Deposit date: | 2016-09-09 | Release date: | 2017-03-01 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.032 Å) | Cite: | A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation. J. Biol. Chem., 292, 2017
|
|
5MK5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mk5 by Molmil](/molmil-images/mine/5mk5) | Structures of DHBN domain of human BLM helicase | Descriptor: | Bloom syndrome protein, IODIDE ION, POTASSIUM ION | Authors: | Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G. | Deposit date: | 2016-12-02 | Release date: | 2017-03-01 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation. J. Biol. Chem., 292, 2017
|
|
4O3M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o3m by Molmil](/molmil-images/mine/4o3m) | Ternary complex of Bloom's syndrome helicase | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*AP*GP*CP*GP*TP*CP*GP*AP*GP*AP*TP*CP*CP*AP*AP*G)-3', 5'-D(*CP*TP*TP*GP*GP*AP*TP*CP*TP*CP*GP*AP*CP*GP*CP*TP*CP*TP*CP*CP*CP*TP*TP*A)-3', ... | Authors: | Swan, M.K, Bertrand, J. | Deposit date: | 2013-12-18 | Release date: | 2014-03-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA. Acta Crystallogr.,Sect.D, 70, 2014
|
|
5U6K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5u6k by Molmil](/molmil-images/mine/5u6k) | |
3WE2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3we2 by Molmil](/molmil-images/mine/3we2) | |
4CDG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4cdg by Molmil](/molmil-images/mine/4cdg) | Crystal structure of the Bloom's syndrome helicase BLM in complex with Nanobody | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BLOOM SYNDROME PROTEIN, NANOBODY, ... | Authors: | Newman, J.A, Savitsky, P, Allerston, C.K, Pike, A.C.W, Pardon, E, Steyaert, J, Arrowsmith, C.H, von Delft, F, Bountra, C, Edwards, A, Gileadi, O. | Deposit date: | 2013-10-31 | Release date: | 2013-11-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.794 Å) | Cite: | Crystal Structure of the Bloom'S Syndrome Helicase Indicates a Role for the Hrdc Domain in Conformational Changes. Nucleic Acids Res., 43, 2015
|
|
3WE3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3we3 by Molmil](/molmil-images/mine/3we3) | |
7AUD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7aud by Molmil](/molmil-images/mine/7aud) | |
4CGZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4cgz by Molmil](/molmil-images/mine/4cgz) | Crystal structure of the Bloom's syndrome helicase BLM in complex with DNA | Descriptor: | 5'-D(*AP*GP*CP*GP*TP*CP*GP*AP*GP*AP*TP*CP)-3', 5'-D(*GP*AP*TP*CP*TP*CP*GP*AP*CP*GP*CP*TP*CP*DT *CP*CP*CP)-3', ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Newman, J.A, Savitsky, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | Deposit date: | 2013-11-27 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal Structure of the Bloom'S Syndrome Helicase Indicates a Role for the Hrdc Domain in Conformational Changes. Nucleic Acids Res., 43, 2015
|
|
2MH9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mh9 by Molmil](/molmil-images/mine/2mh9) | |
2RRD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2rrd by Molmil](/molmil-images/mine/2rrd) | Structure of HRDC domain from human Bloom syndrome protein, BLM | Descriptor: | HRDC domain from Bloom syndrome protein | Authors: | Sato, A, Mishima, M, Nagai, A, Kim, S.Y, Ito, Y, Hakoshima, T, Jee, J.G, Kitano, K. | Deposit date: | 2010-07-19 | Release date: | 2010-09-08 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the HRDC domain of human Bloom syndrome protein BLM J.Biochem., 148, 2010
|
|
2KV2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kv2 by Molmil](/molmil-images/mine/2kv2) | |