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PDB: 15 results

7XV0
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BU of 7xv0 by Molmil
Crystal structure of RPA70N-BLMp1 fusion
Descriptor: Bloom syndrome protein, Replication protein A 70 kDa DNA-binding subunit
Authors:Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C.
Deposit date:2022-05-20
Release date:2023-06-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
7AUC
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BU of 7auc by Molmil
Crystal structure of an engineered helicase domain construct for human Bloom syndrome protein (BLM)
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Chen, X, Oliver, A.W.
Deposit date:2020-11-02
Release date:2020-12-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein.
Elife, 10, 2021
7XUW
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Crystal structure of RPA70N-BLMp2 fusion
Descriptor: fusion protein of Replication protein A 70 kDa DNA-binding subunit and Bloom syndrome protein
Authors:Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C.
Deposit date:2022-05-20
Release date:2023-06-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
5LUP
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BU of 5lup by Molmil
Structures of DHBN domain of human BLM helicase
Descriptor: BLM protein, PHOSPHATE ION, POTASSIUM ION
Authors:Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G.
Deposit date:2016-09-09
Release date:2017-03-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.032 Å)
Cite:A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.
J. Biol. Chem., 292, 2017
5MK5
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BU of 5mk5 by Molmil
Structures of DHBN domain of human BLM helicase
Descriptor: Bloom syndrome protein, IODIDE ION, POTASSIUM ION
Authors:Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G.
Deposit date:2016-12-02
Release date:2017-03-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.
J. Biol. Chem., 292, 2017
4O3M
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Ternary complex of Bloom's syndrome helicase
Descriptor: 1,2-ETHANEDIOL, 5'-D(*AP*GP*CP*GP*TP*CP*GP*AP*GP*AP*TP*CP*CP*AP*AP*G)-3', 5'-D(*CP*TP*TP*GP*GP*AP*TP*CP*TP*CP*GP*AP*CP*GP*CP*TP*CP*TP*CP*CP*CP*TP*TP*A)-3', ...
Authors:Swan, M.K, Bertrand, J.
Deposit date:2013-12-18
Release date:2014-03-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA.
Acta Crystallogr.,Sect.D, 70, 2014
5U6K
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Crystal structure of TopBP1 BRCT4/5 in complex with a BLM phosphopeptide
Descriptor: Bloom Sydrome recQ helicase like protein (BLM), DNA topoisomerase 2-binding protein 1
Authors:Glover, J.N.M, Sun, L, Edwards, R.A.
Deposit date:2016-12-08
Release date:2017-10-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insight into BLM Recognition by TopBP1.
Structure, 25, 2017
3WE2
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BU of 3we2 by Molmil
Structure of BLM RQC domain bound to a phosphate ion
Descriptor: ACETATE ION, Bloom syndrome protein, PHOSPHATE ION
Authors:Kim, S.Y, Hakoshima, T, Kitano, K.
Deposit date:2013-06-28
Release date:2013-11-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the RecQ C-terminal Domain of Human Bloom Syndrome Protein
Sci Rep, 3, 2013
4CDG
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BU of 4cdg by Molmil
Crystal structure of the Bloom's syndrome helicase BLM in complex with Nanobody
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BLOOM SYNDROME PROTEIN, NANOBODY, ...
Authors:Newman, J.A, Savitsky, P, Allerston, C.K, Pike, A.C.W, Pardon, E, Steyaert, J, Arrowsmith, C.H, von Delft, F, Bountra, C, Edwards, A, Gileadi, O.
Deposit date:2013-10-31
Release date:2013-11-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.794 Å)
Cite:Crystal Structure of the Bloom'S Syndrome Helicase Indicates a Role for the Hrdc Domain in Conformational Changes.
Nucleic Acids Res., 43, 2015
3WE3
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BU of 3we3 by Molmil
Structure of BLM RQC domain bound to an arsenate ion
Descriptor: ACETATE ION, ARSENATE, Bloom syndrome protein
Authors:Kim, S.Y, Hakoshima, T, Kitano, K.
Deposit date:2013-06-28
Release date:2013-11-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the RecQ C-terminal Domain of Human Bloom Syndrome Protein
Sci Rep, 3, 2013
7AUD
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BU of 7aud by Molmil
Structure of an engineered helicase domain construct for human Bloom syndrome protein (BLM)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Bloom syndrome protein,Bloom syndrome protein, DNA (5'-D(*GP*TP*AP*CP*CP*CP*GP*AP*TP*GP*TP*GP*T)-3'), ...
Authors:Chen, X, Oliver, A.W.
Deposit date:2020-11-02
Release date:2020-12-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein.
Elife, 10, 2021
4CGZ
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BU of 4cgz by Molmil
Crystal structure of the Bloom's syndrome helicase BLM in complex with DNA
Descriptor: 5'-D(*AP*GP*CP*GP*TP*CP*GP*AP*GP*AP*TP*CP)-3', 5'-D(*GP*AP*TP*CP*TP*CP*GP*AP*CP*GP*CP*TP*CP*DT *CP*CP*CP)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Newman, J.A, Savitsky, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
Deposit date:2013-11-27
Release date:2013-12-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal Structure of the Bloom'S Syndrome Helicase Indicates a Role for the Hrdc Domain in Conformational Changes.
Nucleic Acids Res., 43, 2015
2MH9
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BU of 2mh9 by Molmil
Resonance assignment of RQC domain of human Bloom syndrome protein
Descriptor: Bloom syndrome protein
Authors:Ko, J, Ryu, K.S, Choi, B.S.
Deposit date:2013-11-19
Release date:2014-10-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of the RecQ C-terminal domain of human Bloom syndrome protein.
J.Biomol.Nmr, 58, 2014
2RRD
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BU of 2rrd by Molmil
Structure of HRDC domain from human Bloom syndrome protein, BLM
Descriptor: HRDC domain from Bloom syndrome protein
Authors:Sato, A, Mishima, M, Nagai, A, Kim, S.Y, Ito, Y, Hakoshima, T, Jee, J.G, Kitano, K.
Deposit date:2010-07-19
Release date:2010-09-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the HRDC domain of human Bloom syndrome protein BLM
J.Biochem., 148, 2010
2KV2
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BU of 2kv2 by Molmil
Solution Structure of the human BLM HRDC domain
Descriptor: Bloom syndrome protein
Authors:Kim, Y.M, Choi, B.-S.
Deposit date:2010-03-04
Release date:2010-12-15
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure and function of the regulatory HRDC domain from human Bloom syndrome protein
Nucleic Acids Res., 38, 2010

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PDB entries from 2024-07-17

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