4CGZ
Crystal structure of the Bloom's syndrome helicase BLM in complex with DNA
Summary for 4CGZ
Entry DOI | 10.2210/pdb4cgz/pdb |
Descriptor | BLOOM'S SYNDROME HELICASE, 5'-D(*AP*GP*CP*GP*TP*CP*GP*AP*GP*AP*TP*CP)-3', 5'-D(*GP*AP*TP*CP*TP*CP*GP*AP*CP*GP*CP*TP*CP*DT *CP*CP*CP)-3', ... (5 entities in total) |
Functional Keywords | hydrolase-dna complex, hydrolase/dna |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus : P54132 |
Total number of polymer chains | 3 |
Total formula weight | 84971.42 |
Authors | Newman, J.A.,Savitsky, P.,Krojer, T.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. (deposition date: 2013-11-27, release date: 2013-12-11, Last modification date: 2023-12-20) |
Primary citation | Newman, J.A.,Savitsky, P.,Allerston, C.K.,Bizard, A.H.,Ozer, O.,Sarlos, K.,Liu, Y.,Pardon, E.,Steyaert, J.,Hickson, I.D.,Gileadi, O. Crystal Structure of the Bloom'S Syndrome Helicase Indicates a Role for the Hrdc Domain in Conformational Changes. Nucleic Acids Res., 43:5221-, 2015 Cited by PubMed: 25901030DOI: 10.1093/NAR/GKV373 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
Download full validation report