4CGZ
Crystal structure of the Bloom's syndrome helicase BLM in complex with DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BLOOM'S SYNDROME HELICASE | polymer | 665 | 75692.1 | 1 | UniProt (P54132) Pfam (PF00270) Pfam (PF00271) Pfam (PF16124) Pfam (PF09382) Pfam (PF00570) | HOMO SAPIENS (HUMAN) | DNA HELICASE, RECQ-LIKE TYPE 2, RECQ2, RECQ PROTEIN-LIKE 3 |
| 2 | B (B) | 5'-D(*AP*GP*CP*GP*TP*CP*GP*AP*GP*AP*TP*CP)-3' | polymer | 12 | 3687.4 | 1 | SYNTHETIC CONSTRUCT | ||
| 3 | C (C) | 5'-D(*GP*AP*TP*CP*TP*CP*GP*AP*CP*GP*CP*TP*CP*DT *CP*CP*CP)-3' | polymer | 17 | 5099.3 | 1 | SYNTHETIC CONSTRUCT | ||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) |
Sequence modifications
A: 636 - 1298 (UniProt: P54132)
| PDB | External Database | Details |
|---|---|---|
| Ser 634 | - | expression tag |
| Met 635 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 84478.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 492.6 | |
| All* | Total formula weight | 84971.4 |
