6Z2W
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![BU of 6z2w by Molmil](/molmil-images/mine/6z2w) | Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP | Descriptor: | DNA damage checkpoint protein LCD1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Yates, L.A, Zhang, X. | Deposit date: | 2020-05-18 | Release date: | 2020-11-11 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.82 Å) | Cite: | Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase. Nat.Struct.Mol.Biol., 28, 2021
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6Z2X
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![BU of 6z2x by Molmil](/molmil-images/mine/6z2x) | Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP (State II) | Descriptor: | DNA damage checkpoint protein LCD1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Yates, L.A, Zhang, X. | Deposit date: | 2020-05-18 | Release date: | 2020-11-11 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase. Nat.Struct.Mol.Biol., 28, 2021
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6Z3A
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![BU of 6z3a by Molmil](/molmil-images/mine/6z3a) | Mec1-Ddc2 (wild-type) in complex with AMP-PNP | Descriptor: | DNA damage checkpoint protein LCD1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase MEC1, ... | Authors: | Yates, L.A, Zhang, X. | Deposit date: | 2020-05-19 | Release date: | 2020-11-11 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase. Nat.Struct.Mol.Biol., 28, 2021
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5X6O
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![BU of 5x6o by Molmil](/molmil-images/mine/5x6o) | Intact ATR/Mec1-ATRIP/Ddc2 complex | Descriptor: | DNA damage checkpoint protein LCD1, Serine/threonine-protein kinase MEC1 | Authors: | Wang, X, Ran, T, Cai, G. | Deposit date: | 2017-02-22 | Release date: | 2017-12-20 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | 3.9 angstrom structure of the yeast Mec1-Ddc2 complex, a homolog of human ATR-ATRIP. Science, 358, 2017
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7WZW
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![BU of 7wzw by Molmil](/molmil-images/mine/7wzw) | Cryo-EM structure of MEC1-DDC2-MMS | Descriptor: | DNA damage checkpoint protein LCD1, Serine/threonine-protein kinase MEC1 | Authors: | Zhang, Q, Zhang, Q. | Deposit date: | 2022-02-19 | Release date: | 2023-03-01 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structures of Mec1/ATR kinase endogenously stimulated by different genotoxins. Cell Discov, 8, 2022
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7WZR
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![BU of 7wzr by Molmil](/molmil-images/mine/7wzr) | Cryo-EM structure of Mec1-HU | Descriptor: | DNA damage checkpoint protein LCD1, Serine/threonine-protein kinase MEC1 | Authors: | Zhang, Q, Zhang, Q. | Deposit date: | 2022-02-19 | Release date: | 2023-03-08 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structures of Mec1/ATR kinase endogenously stimulated by different genotoxins. Cell Discov, 8, 2022
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