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PDB: 2 results

6NJ0
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BU of 6nj0 by Molmil
Wild-type E. coli MenE with bound m phenylether-linked analogue of OSB-AMS
Descriptor: 2-succinylbenzoate--CoA ligase, 5'-O-{3-[3-(2-carboxyphenyl)-3-oxopropyl]phenyl}adenosine
Authors:Si, Y, Yin, Y, French, J.B, Tonge, P.J.
Deposit date:2019-01-02
Release date:2019-04-10
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure-Based Design, Synthesis, and Biological Evaluation of Non-Acyl Sulfamate Inhibitors of the Adenylate-Forming Enzyme MenE.
Biochemistry, 58, 2019
5C5H
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BU of 5c5h by Molmil
R195K E. coli MenE with bound OSB-AMS
Descriptor: 2-succinylbenzoate--CoA ligase, 5'-O-{[4-(2-carboxyphenyl)-4-oxobutanoyl]sulfamoyl}adenosine, MAGNESIUM ION
Authors:Matarlo, J.S, Shek, R, Rajashankar, K.R, Tonge, P.J, French, J.B.
Deposit date:2015-06-19
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Mechanism of MenE Inhibition by Acyl-Adenylate Analogues and Discovery of Novel Antibacterial Agents.
Biochemistry, 54, 2015

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