5C5H

R195K E. coli MenE with bound OSB-AMS

Summary for 5C5H

• Entry DOI: 10.2210/pdb5c5h/pdb
• Descriptor: 2-succinylbenzoate--CoA ligase, MAGNESIUM ION, 5'-O-{[4-(2-carboxyphenyl)-4-oxobutanoyl]sulfamoyl}adenosine, ... (4 entities in total)
• Functional Keywords: ligase
• Biological source: Escherichia coli (strain K12)
• Total number of polymer chains: 2
• Total formula weight: 102041.24

Authors

Matarlo, J.S.,Shek, R.,Rajashankar, K.R.,Tonge, P.J.,French, J.B. (deposition date: 2015-06-19, release date: 2015-10-07, Last modification date: 2023-09-27)

• Primary citation: Matarlo, J.S.,Evans, C.E.,Sharma, I.,Lavaud, L.J.,Ngo, S.C.,Shek, R.,Rajashankar, K.R.,French, J.B.,Tan, D.S.,Tonge, P.J.; Mechanism of MenE Inhibition by Acyl-Adenylate Analogues and Discovery of Novel Antibacterial Agents.; Biochemistry, 54:6514-6524, 2015; PubMed: 26394156; DOI: 10.1021/acs.biochem.5b00966

Experimental method

X-RAY DIFFRACTION (2.401 Å)