5C5H
R195K E. coli MenE with bound OSB-AMS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0008756 | molecular_function | o-succinylbenzoate-CoA ligase activity |
| A | 0009234 | biological_process | menaquinone biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0016877 | molecular_function | ligase activity, forming carbon-sulfur bonds |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0042802 | molecular_function | identical protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0008756 | molecular_function | o-succinylbenzoate-CoA ligase activity |
| B | 0009234 | biological_process | menaquinone biosynthetic process |
| B | 0016874 | molecular_function | ligase activity |
| B | 0016877 | molecular_function | ligase activity, forming carbon-sulfur bonds |
| B | 0032991 | cellular_component | protein-containing complex |
| B | 0042802 | molecular_function | identical protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 501 |
| Chain | Residue |
| A | ARG9 |
| A | CYS34 |
| A | ASP38 |
| A | GLN74 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | binding site for residue 4YB A 502 |
| Chain | Residue |
| A | GLY247 |
| A | ALA248 |
| A | ALA249 |
| A | GLY268 |
| A | TYR269 |
| A | GLY270 |
| A | LEU271 |
| A | THR272 |
| A | SER276 |
| A | THR277 |
| A | ASP336 |
| A | ILE347 |
| A | ARG350 |
| A | LYS437 |
| A | HOH605 |
| A | HOH614 |
| A | HOH623 |
| A | HOH661 |
| A | HOH666 |
| A | HOH677 |
| A | SER188 |
| A | LEU223 |
| A | LEU244 |
| A | LEU245 |
| A | GLY246 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 501 |
| Chain | Residue |
| A | GLN132 |
| A | PRO133 |
| A | THR134 |
| A | HOH602 |
| B | GLY48 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 502 |
| Chain | Residue |
| B | ASN61 |
| B | PRO183 |
| B | HOH721 |
| site_id | AC5 |
| Number of Residues | 26 |
| Details | binding site for residue 4YB B 503 |
| Chain | Residue |
| B | LEU182 |
| B | HIS186 |
| B | SER188 |
| B | LEU223 |
| B | LEU244 |
| B | LEU245 |
| B | GLY246 |
| B | GLY247 |
| B | ALA248 |
| B | ALA249 |
| B | GLY268 |
| B | TYR269 |
| B | GLY270 |
| B | LEU271 |
| B | THR272 |
| B | SER276 |
| B | THR277 |
| B | VAL289 |
| B | ASP336 |
| B | ARG350 |
| B | LYS437 |
| B | HOH606 |
| B | HOH630 |
| B | HOH654 |
| B | HOH663 |
| B | HOH672 |
Functional Information from PROSITE/UniProt
| site_id | PS00455 |
| Number of Residues | 12 |
| Details | AMP_BINDING Putative AMP-binding domain signature. MTLTSGSTGlPK |
| Chain | Residue | Details |
| A | MET139-LYS150 |
