6NJ0
Wild-type E. coli MenE with bound m phenylether-linked analogue of OSB-AMS
Summary for 6NJ0
Entry DOI | 10.2210/pdb6nj0/pdb |
Descriptor | 2-succinylbenzoate--CoA ligase, 5'-O-{3-[3-(2-carboxyphenyl)-3-oxopropyl]phenyl}adenosine (3 entities in total) |
Functional Keywords | mene, e. coli, menaquinone, ligase |
Biological source | Escherichia coli (strain K12) |
Total number of polymer chains | 1 |
Total formula weight | 50755.97 |
Authors | Si, Y.,Yin, Y.,French, J.B.,Tonge, P.J. (deposition date: 2019-01-02, release date: 2019-04-10, Last modification date: 2024-03-13) |
Primary citation | Evans, C.E.,Si, Y.,Matarlo, J.S.,Yin, Y.,French, J.B.,Tonge, P.J.,Tan, D.S. Structure-Based Design, Synthesis, and Biological Evaluation of Non-Acyl Sulfamate Inhibitors of the Adenylate-Forming Enzyme MenE. Biochemistry, 58:1918-1930, 2019 Cited by PubMed: 30912442DOI: 10.1021/acs.biochem.9b00003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
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