6NJ0

Wild-type E. coli MenE with bound m phenylether-linked analogue of OSB-AMS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0008756	molecular_function	o-succinylbenzoate-CoA ligase activity
A	0009234	biological_process	menaquinone biosynthetic process
A	0016878	molecular_function	acid-thiol ligase activity
A	0032991	cellular_component	protein-containing complex
A	0042802	molecular_function	identical protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	binding site for residue KOY A 501

Chain	Residue
A	LEU182
A	TYR269
A	GLY270
A	THR272
A	SER276
A	THR277
A	VAL289
A	ASP336
A	ARG350
A	HOH639
A	HOH643
A	SER188
A	HOH743
A	ARG195
A	LEU223
A	LEU244
A	GLY246
A	ALA248
A	ALA249
A	GLY268

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Functional Information from PROSITE/UniProt

site_id	PS00455
Number of Residues	12
Details	AMP_BINDING Putative AMP-binding domain signature. MTLTSGSTGlPK

Chain	Residue	Details
A	MET139-LYS150

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00731","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30912442","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6NJ0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26394156","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30912442","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5C5H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6NJ0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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