7Q1D
| Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Aminoglycoside N(3)-acetyltransferase III, CHLORIDE ION, ... | Authors: | Pontillo, N, Guskov, A. | Deposit date: | 2021-10-18 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | 3-N-alkylation in aminoglycoside antibiotic neomycin B overcomes bacterial resistance mediated by acetyltransferase (3) IIIa To Be Published
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7Q1X
| Acetyltrasferase(3) type IIIa in complex with neomycin B | Descriptor: | Aminoglycoside N(3)-acetyltransferase III, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Pontillo, N, Guskov, A. | Deposit date: | 2021-10-21 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The 3-N-alkylation of the neomycin B outmaneuvers the aminoglycoside resistant enzyme acetyltransferase(3)IIIa via an unexpected mechanism To Be Published
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7MQK
| AAC(3)-IIIa in complex with CoA and sisomicin | Descriptor: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, Aminoglycoside N(3)-acetyltransferase III, COENZYME A, ... | Authors: | Zielinski, M, Berghuis, A.M. | Deposit date: | 2021-05-05 | Release date: | 2022-07-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural elucidation of substrate-bound aminoglycoside acetyltransferase (3)-IIIa. Plos One, 17, 2022
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7MQM
| AAC(3)-IIIa in complex with CoA and gentamicin | Descriptor: | Aminoglycoside N(3)-acetyltransferase III, COENZYME A, GLYCEROL, ... | Authors: | Zielinski, M, Berghuis, A.M. | Deposit date: | 2021-05-05 | Release date: | 2022-07-06 | Last modified: | 2022-08-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural elucidation of substrate-bound aminoglycoside acetyltransferase (3)-IIIa. Plos One, 17, 2022
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7MQL
| AAC(3)-IIIa in complex with CoA and neomycin | Descriptor: | Aminoglycoside N(3)-acetyltransferase III, COENZYME A, FORMIC ACID, ... | Authors: | Zielinski, M, Berghuis, A.M. | Deposit date: | 2021-05-05 | Release date: | 2022-07-06 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural elucidation of substrate-bound aminoglycoside acetyltransferase (3)-IIIa. Plos One, 17, 2022
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7Q10
| Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B | Descriptor: | 3N methyl nemycin B, ACETATE ION, Aminoglycoside N(3)-acetyltransferase III, ... | Authors: | Pontillo, N, Guskov, A. | Deposit date: | 2021-10-17 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | 3-N-alkylation in aminoglycoside antibiotic neomycin B overcomes bacterial resistance mediated by acetyltransferase (3) IIIa To Be Published
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7Q0Q
| Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B | Descriptor: | 3N methyl nemycin B, ACETATE ION, Aminoglycoside N(3)-acetyltransferase III, ... | Authors: | Pontillo, N, Guskov, A. | Deposit date: | 2021-10-16 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | The 3-N-alkylation of the neomycin B outmaneuvers the aminoglycoside resistant enzyme acetyltransferase(3)IIIa via an unexpected mechanism To Be Published
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