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PDB: 3 results

3FE3
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BU of 3fe3 by Molmil
Crystal structure of the kinase MARK3/Par-1: T211A-S215A double mutant
Descriptor: MAP/microtubule affinity-regulating kinase 3
Authors:Nugoor, C, Marx, A, Panneerselvam, S, Mandelkow, E.-M, Mandelkow, E.
Deposit date:2008-11-27
Release date:2008-12-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the kinase MARK3/Par-1: T211A-S215A double mutant
TO BE PUBLISHED
7P1L
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BU of 7p1l by Molmil
The MARK3 Kinase Domain Bound To AA-CS-1-008
Descriptor: 1,2-ETHANEDIOL, 5-Bromo-4-N-[2-(1H-imidazol-5-yl)ethyl]-2-N-[3-(morpholin-4-ylmethyl)phenyl]pyrimidine-2,4-diamine, MAP/microtubule affinity-regulating kinase 3
Authors:Dederer, V, Preuss, F, Chatterjee, D, Vlassova, A, Mathea, S, Axtman, A, Knapp, S.
Deposit date:2021-07-01
Release date:2021-07-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Identification of Pyrimidine-Based Lead Compounds for Understudied Kinases Implicated in Driving Neurodegeneration.
J.Med.Chem., 65, 2022
2QNJ
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Kinase and Ubiquitin-associated domains of MARK3/Par-1
Descriptor: MAP/microtubule affinity-regulating kinase 3
Authors:Murphy, J.M, Ceccarelli, D.F.J, Sicheri, F, Pawson, T.
Deposit date:2007-07-18
Release date:2007-09-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational instability of the MARK3 UBA domain compromises ubiquitin recognition and promotes interaction with the adjacent kinase domain
Proc.Natl.Acad.Sci.Usa, 104, 2007

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