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PDB: 19 results

8IJP
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BU of 8ijp by Molmil
Structure of DNA binding domain of McrBC endonuclease bound to DNA: L68Y mutant
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*CP*CP*GP*GP*TP*CP*TP*C)-3'), ...
Authors:Adhav, V.A, Saikrishnan, K.
Deposit date:2023-02-27
Release date:2024-02-28
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis of target recognition by the DNA binding domain of McrBC
To Be Published
6GCF
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BU of 6gcf by Molmil
DNA binding domain of restriction endonuclease McrBC in complex with N4-methylcytosine DNA
Descriptor: 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*(C34)P*CP*GP*GP*TP*CP*TP*C)-3')
Authors:Sasnauskas, G.
Deposit date:2018-04-17
Release date:2018-09-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Recognition of modified cytosine variants by the DNA-binding domain of methyl-directed endonuclease McrBC.
FEBS Lett., 592, 2018
6GCE
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BU of 6gce by Molmil
DNA binding domain of restriction endonuclease McrBC in complex with 5-formylcytosine DNA
Descriptor: 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*(5FC)P*CP*GP*GP*TP*CP*TP*C)-3')
Authors:Sasnauskas, G.
Deposit date:2018-04-17
Release date:2018-09-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Recognition of modified cytosine variants by the DNA-binding domain of methyl-directed endonuclease McrBC.
FEBS Lett., 592, 2018
8IJO
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BU of 8ijo by Molmil
Structure of DNA binding domain of McrBC endonuclease bound to DNA: Y41F-L68F double mutant
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*CP*CP*GP*GP*TP*CP*TP*C)-3'), ...
Authors:Adhav, V.A, Saikrishnan, K.
Deposit date:2023-02-27
Release date:2024-02-28
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis of target recognition by the DNA binding domain of McrBC
To Be Published
6GCD
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BU of 6gcd by Molmil
DNA binding domain of restriction endonuclease McrBC in complex with 5-hydroxymethylcytosine DNA
Descriptor: 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*GP*AP*GP*AP*(5HC)P*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*(5HC)P*CP*GP*GP*TP*CP*TP*C)-3')
Authors:Sasnauskas, G, Manakova, E.
Deposit date:2018-04-17
Release date:2018-09-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Recognition of modified cytosine variants by the DNA-binding domain of methyl-directed endonuclease McrBC.
FEBS Lett., 592, 2018
8IK8
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BU of 8ik8 by Molmil
Structure of DNA binding domain of McrBC endonuclease bound to DNA: L68F mutant
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*CP*CP*GP*GP*TP*CP*TP*C)-3'), ...
Authors:Adhav, V.A, Saikrishnan, K.
Deposit date:2023-02-28
Release date:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of target recognition by the DNA binding domain of McrBC
To Be Published
8IK4
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BU of 8ik4 by Molmil
Structure of DNA binding domain of McrBC endonuclease bound to hemimethylated DNA: L68F mutant
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(*AP*GP*AP*(5CM)P*CP*GP*GP*TP*AP*G)-3'), DNA (5'-D(*CP*TP*AP*CP*CP*GP*GP*TP*CP*T)-3'), ...
Authors:Adhav, V.A, Saikrishnan, K.
Deposit date:2023-02-28
Release date:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of target recognition by the DNA binding domain of McrBC
To Be Published
8IKD
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BU of 8ikd by Molmil
Structure of DNA binding domain of McrBC endonuclease bound to DNA: Y41F-L68Y double mutant
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*CP*CP*GP*GP*TP*CP*TP*C)-3'), ...
Authors:Adhav, V.A, Saikrishnan, K.
Deposit date:2023-02-28
Release date:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of target recognition by the DNA binding domain of McrBC
To Be Published
3SSC
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BU of 3ssc by Molmil
DNA binding domain of restriction endonuclease bound to DNA
Descriptor: 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*AP*GP*CP*TP*AP*(5CM)P*CP*GP*GP*TP*CP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*GP*AP*(5CM)P*CP*GP*GP*TP*AP*GP*C)-3')
Authors:Sukackaite, R, Grazulis, S, Siksnys, V.
Deposit date:2011-07-08
Release date:2012-05-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine.
Nucleic Acids Res., 40, 2012
3SSD
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BU of 3ssd by Molmil
DNA binding domain of restriction endonuclease bound to DNA
Descriptor: 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*A*GP*CP*TP*AP*CP*CP*GP*GP*TP*CP*TP*C)-3'), DNA (5'-D(*T*GP*AP*GP*AP*(5CM)P*CP*GP*GP*TP*AP*GP*C)-3')
Authors:Sukackaite, R, Grazulis, S, Siksnys, V.
Deposit date:2011-07-08
Release date:2012-05-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine.
Nucleic Acids Res., 40, 2012
3SSE
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BU of 3sse by Molmil
DNA binding domain of restriction endonuclease bound to DNA
Descriptor: 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*A*GP*CP*TP*AP*CP*CP*GP*GP*TP*CP*TP*C)-3'), DNA (5'-D(*T*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3')
Authors:Sukackaite, R, Grazulis, S, Siksnys, V.
Deposit date:2011-07-08
Release date:2012-05-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine.
Nucleic Acids Res., 40, 2012
6UT6
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BU of 6ut6 by Molmil
Cryo-EM structure of the Escherichia coli McrBC complex
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Niu, Y, Suzuki, H, Hosford, C.J, Chappie, J.S, Walz, T.
Deposit date:2019-10-29
Release date:2020-10-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structural asymmetry governs the assembly and GTPase activity of McrBC restriction complexes.
Nat Commun, 11, 2020
6HZ4
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BU of 6hz4 by Molmil
Structure of McrBC without DNA binding domains (one half of the full complex)
Descriptor: 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A.
Deposit date:2018-10-22
Release date:2019-07-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
6HZ5
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BU of 6hz5 by Molmil
Structure of McrBC without DNA binding domains (Class 1)
Descriptor: 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A.
Deposit date:2018-10-22
Release date:2019-07-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
6HZ6
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BU of 6hz6 by Molmil
Structure of McrBC without DNA binding domains (Class 2)
Descriptor: 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A.
Deposit date:2018-10-22
Release date:2019-07-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
6HZ8
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BU of 6hz8 by Molmil
Structure of McrBC without DNA binding domains (Class 4)
Descriptor: 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A.
Deposit date:2018-10-22
Release date:2019-07-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
6HZ7
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BU of 6hz7 by Molmil
Structure of McrBC without DNA binding domains (Class 3)
Descriptor: 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A.
Deposit date:2018-10-22
Release date:2019-07-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
7VSR
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BU of 7vsr by Molmil
Structure of McrBC (stalkless mutant)
Descriptor: 5-methylcytosine-specific restriction enzyme B, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Saikrishnan, K, Adhav, V.A, Bose, S, Kutti R, V.
Deposit date:2021-10-27
Release date:2023-02-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure of McrBC (stalkless mutant)
To Be Published
6HZ9
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BU of 6hz9 by Molmil
Structure of McrBC without DNA binding domains (Class 5)
Descriptor: 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A.
Deposit date:2018-10-22
Release date:2019-07-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019

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PDB entries from 2024-07-31

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