6HZ8

Structure of McrBC without DNA binding domains (Class 4)

Summary for 6HZ8

• Entry DOI: 10.2210/pdb6hz8/pdb
• EMDB information: 0314
• Descriptor: 5-methylcytosine-specific restriction enzyme B, Protein McrC, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (5 entities in total)
• Functional Keywords: aaa+ superfamily, restriction enzyme, dna binding protein
• Biological source: Escherichia coli (strain K12); More
• Total number of polymer chains: 14
• Total formula weight: 516327.37

Authors

Itoh, Y.,Nirwan, N.,Saikrishnan, K.,Amunts, A. (deposition date: 2018-10-22, release date: 2019-07-24, Last modification date: 2019-11-06)

• Primary citation: Nirwan, N.,Itoh, Y.,Singh, P.,Bandyopadhyay, S.,Vinothkumar, K.R.,Amunts, A.,Saikrishnan, K.; Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.; Nat Commun, 10:3058-3058, 2019; PubMed: 31296862; DOI: 10.1038/s41467-019-11084-1

Experimental method

ELECTRON MICROSCOPY (4.3 Å)