3FPC
| Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-294 of T. brockii ADH by E. histolytica ADH | Descriptor: | 1,2-ETHANEDIOL, CACODYLATE ION, IMIDAZOLE, ... | Authors: | Felix, F, Goihberg, E, Shimon, L, Burstein, Y. | Deposit date: | 2009-01-05 | Release date: | 2010-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms Biochemistry, 49, 2010
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2OUI
| D275P mutant of alcohol dehydrogenase from protozoa Entamoeba histolytica | Descriptor: | 1,2-ETHANEDIOL, CACODYLATE ION, CHLORIDE ION, ... | Authors: | Frolow, F, Shimon, L, Burstein, Y, Goihberg, E, Peretz, M, Dym, O. | Deposit date: | 2007-02-11 | Release date: | 2008-02-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution. Proteins, 72, 2008
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1Y9A
| Alcohol Dehydrogenase from Entamoeba histolotica in complex with cacodylate | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CACODYLATE ION, ... | Authors: | Shimon, L.J, Peretz, M, Goihberg, E, Burstein, Y, Frolow, F. | Deposit date: | 2004-12-15 | Release date: | 2006-01-17 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structure of alcohol dehydrogenase from Entamoeba histolytica. Acta Crystallogr.,Sect.D, 62, 2006
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7UTC
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7UUT
| Ternary complex crystal structure of secondary alcohol dehydrogenases from the Thermoanaerobacter ethanolicus mutants C295A and I86A provides better understanding of catalytic mechanism | Descriptor: | (2R)-pentan-2-ol, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ... | Authors: | Dinh, T, Phillips, R, Rahn, K. | Deposit date: | 2022-04-28 | Release date: | 2022-05-11 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Crystallographic snapshots of ternary complexes of thermophilic secondary alcohol dehydrogenase from Thermoanaerobacter pseudoethanolicus reveal the dynamics of ligand exchange and the proton relay network. Proteins, 90, 2022
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3FPL
| Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-295 of C. beijerinckii ADH by T. brockii ADH | Descriptor: | 1,2-ETHANEDIOL, CACODYLATE ION, CHLORIDE ION, ... | Authors: | Felix, F, Goihberg, E, Shimon, L, Burstein, Y. | Deposit date: | 2009-01-05 | Release date: | 2010-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms Biochemistry, 49, 2010
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7XY9
| Cryo-EM structure of secondary alcohol dehydrogenases TbSADH after carrier-free immobilization based on weak intermolecular interactions | Descriptor: | MAGNESIUM ION, NADP-dependent isopropanol dehydrogenase, ZINC ION | Authors: | Chen, Q, Li, X, Yang, F, Qu, G, Sun, Z.T, Wang, Y.J. | Deposit date: | 2022-06-01 | Release date: | 2023-06-07 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.12 Å) | Cite: | Active and stable alcohol dehydrogenase-assembled hydrogels via synergistic bridging of triazoles and metal ions. Nat Commun, 14, 2023
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3FTN
| Q165E/S254K Double Mutant Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-295 of T. brockii ADH by C. beijerinckii ADH | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Frolow, F, Goihberg, E, Shimon, L, Burstein, Y. | Deposit date: | 2009-01-13 | Release date: | 2010-01-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.192 Å) | Cite: | Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms. Biochemistry, 49, 2010
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3FSR
| Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-295 of T. brockii ADH by C. beijerinckii ADH | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, NADP-dependent alcohol dehydrogenase, ... | Authors: | Frolow, F, Greenblatt, H, Goihberg, E, Burstein, Y. | Deposit date: | 2009-01-11 | Release date: | 2010-01-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms Biochemistry, 49, 2010
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7UX4
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1YKF
| NADP-DEPENDENT ALCOHOL DEHYDROGENASE FROM THERMOANAEROBIUM BROCKII | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-DEPENDENT ALCOHOL DEHYDROGENASE, ZINC ION | Authors: | Korkhin, Y, Frolow, F. | Deposit date: | 1996-03-25 | Release date: | 1998-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | NADP-dependent bacterial alcohol dehydrogenases: crystal structure, cofactor-binding and cofactor specificity of the ADHs of Clostridium beijerinckii and Thermoanaerobacter brockii. J.Mol.Biol., 278, 1998
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7F3P
| Crystal structure of a nadp-dependent alcohol dehydrogenase mutant in apo form | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent isopropanol dehydrogenase, ZINC ION | Authors: | Han, X, Bi, Y, Wei, H.L, Gao, J, Li, Q, Qu, G, Sun, Z.T, Liu, W.D. | Deposit date: | 2021-06-16 | Release date: | 2021-10-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Unlocking the Stereoselectivity and Substrate Acceptance of Enzymes: Proline-Induced Loop Engineering Test. Angew.Chem.Int.Ed.Engl., 61, 2022
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7XL5
| Crystal structure of the H42T/A85G/I86A mutant of a nadp-dependent alcohol dehydrogenase | Descriptor: | NADP-dependent isopropanol dehydrogenase | Authors: | Jiang, Y.Y, Qu, G, Li, X, Sun, Z.T, Han, X, Liu, W.D. | Deposit date: | 2022-04-21 | Release date: | 2023-05-31 | Last modified: | 2024-06-12 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | Engineering the hydrogen transfer pathway of an alcohol dehydrogenase to increase activity by rational enzyme design Mol Catal, 530, 2022
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2NVB
| Contribution of Pro275 to the Thermostability of the Alcohol Dehydrogenases (ADHs) | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent alcohol dehydrogenase, ZINC ION | Authors: | Goihberg, E, Tel-Or, S, Peretz, M, Frolow, F, Dym, O, Burstein, Y, Israel Structural Proteomics Center (ISPC) | Deposit date: | 2006-11-12 | Release date: | 2007-11-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution Proteins, 72, 2008
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6SDM
| NADH-dependent variant of TBADH | Descriptor: | NADP-dependent isopropanol dehydrogenase, ZINC ION | Authors: | Selles Vidal, L, Murray, J.W, Heap, J.T. | Deposit date: | 2019-07-28 | Release date: | 2020-08-26 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Versatile selective evolutionary pressure using synthetic defect in universal metabolism. Nat Commun, 12, 2021
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1BXZ
| CRYSTAL STRUCTURE OF A THERMOPHILIC ALCOHOL DEHYDROGENASE SUBSTRATE COMPLEX FROM THERMOANAEROBACTER BROCKII | Descriptor: | 2-BUTANOL, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Li, C, Heatwole, J, Soelaiman, S, Shoham, M. | Deposit date: | 1998-10-09 | Release date: | 2000-02-18 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Crystal structure of a thermophilic alcohol dehydrogenase substrate complex suggests determinants of substrate specificity and thermostability. Proteins, 37, 1999
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