PDB Search results for query - Protein Data Bank Japan

PDB: 3 results

The 1.9 A structure of Kex2 in complex with an Ac-R-E-R-K-chloromethyl ketone inhibitor.
Descriptor:	2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ac-RERK-CMK inhibitor, ...
Authors:	Wheatley, J.L, Holyoak, T.
Deposit date:	2006-09-14
Release date:	2007-05-01
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Differential P1 arginine and lysine recognition in the prototypical proprotein convertase Kex2. Proc.Natl.Acad.Sci.Usa, 104, 2007

The 2.2 A crystal structure of Kex2 protease in complex with Ac-Arg-Glu-Lys-boroArg peptidyl boronic acid inhibitor
Descriptor:	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:	Holyoak, T, Kettner, C.A, Petsko, G.A, Fuller, R.S, Ringe, D.
Deposit date:	2003-10-14
Release date:	2004-03-09
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Structural Basis for Differences in Substrate Selectivity in Kex2 and Furin Protein Convertases Biochemistry, 43, 2004

The 2.4 Angstrom Crystal Structure of Kex2 in complex with a peptidyl-boronic acid inhibitor
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ac-Ala-Lys-boroArg N-acetylated boronic acid peptide inhibitor, ...
Authors:	Holyoak, T, Wilson, M.A, Fenn, T.D, Kettner, C.A, Petsko, G.A, Fuller, R.S, Ringe, D.
Deposit date:	2003-03-21
Release date:	2003-06-17
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	2.4 A Resolution Crystal Structure of the Prototypical Hormone-Processing Protease Kex2 in Complex with an Ala-Lys-Arg Boronic Acid Inhibitor Biochemistry, 42, 2003