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PDB: 3 results

6SGR
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BU of 6sgr by Molmil
Cryo-EM structure of Escherichia coli AcrBZ and DARPin in Saposin A-nanodisc with cardiolipin
Descriptor: DARPin, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrB
Authors:Szewczak-Harris, A, Du, D, Newman, C, Neuberger, A, Luisi, B.F.
Deposit date:2019-08-05
Release date:2020-05-13
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Interactions of a Bacterial RND Transporter with a Transmembrane Small Protein in a Lipid Environment.
Structure, 28, 2020
4C48
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BU of 4c48 by Molmil
Crystal structure of AcrB-AcrZ complex
Descriptor: ACRIFLAVINE RESISTANCE PROTEIN B, DARPIN, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Du, D, James, N, Klimont, E, Luisi, B.F.
Deposit date:2013-09-02
Release date:2014-04-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the AcrAB-TolC multidrug efflux pump.
Nature, 509, 2014
5NG5
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BU of 5ng5 by Molmil
multi-drug efflux; membrane transport; RND superfamily; Drug resistance
Descriptor: 6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrA, ...
Authors:Wang, Z, Fan, G, Hryc, C.F, Blaza, J.N, Serysheva, I.I, Schmid, M.F, Chiu, W, Luisi, B.F, Du, D.
Deposit date:2017-03-16
Release date:2017-04-19
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump.
Elife, 6, 2017

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