2OJP
 
 | | The crystal structure of a dimeric mutant of Dihydrodipicolinate synthase from E.coli- DHDPS-L197Y | | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL | | Authors: | Griffin, M.D.W, Dobson, R.C.J, Antonio, L, Perugini, M.A, Jameson, G.B, Gerrard, J.A. | | Deposit date: | 2007-01-13 | | Release date: | 2008-01-01 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Evolution of quaternary structure in a homotetrameric enzyme.
J.Mol.Biol., 380, 2008
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2PUR
 | | Structure of dihydrodipicolinate synthase mutant Thr44Ser at 1.7 A. | | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A. | | Deposit date: | 2007-05-09 | | Release date: | 2008-05-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Specificity versus catalytic potency: The role of threonine 44 in Escherichia coli dihydrodipicolinate synthase mediated catalysis.
Biochimie, 91, 2009
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7JZ7
 | | Dihydrodipicolinate synthase mutant S48F | | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase, GLYCEROL, POTASSIUM ION | | Authors: | Board, A.J, Dobson, R.C.J. | | Deposit date: | 2020-09-01 | | Release date: | 2021-10-06 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Mapping the unchartered waters of dihydrodipicolinate synthase: a novel mechanism of allosteric inhibition.
To Be Published
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7JZ8
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7JZG
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7JZF
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7JZ9
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7JZA
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1YXC
 | | Structure of E. coli dihydrodipicolinate synthase to 1.9 A | | Descriptor: | CHLORIDE ION, POTASSIUM ION, dihydrodipicolinate synthase | | Authors: | Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A. | | Deposit date: | 2005-02-20 | | Release date: | 2005-08-02 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance.
Acta Crystallogr.,Sect.D, 61, 2005
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2ATS
 | | Dihydrodipicolinate synthase co-crystallised with (S)-lysine | | Descriptor: | CHLORIDE ION, D-LYSINE, POTASSIUM ION, ... | | Authors: | Devenish, S.R.A, Dobson, R.C.J, Jameson, G.B, Gerrard, J.A. | | Deposit date: | 2005-08-26 | | Release date: | 2006-09-19 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The co-crystallisation of (S)-lysine-bound dihydrodipicolinate synthase from E. coli indicates that domain movements are not responsible for (S)-lysine inhibition
To be published
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7JZD
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7JZB
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2A6N
 | | Dihydrodipicolinate synthase (E. coli)- mutant R138A | | Descriptor: | Dihydrodipicolinate synthase, POTASSIUM ION | | Authors: | Dobson, R.C, Devenish, S.R, Turner, L.A, Clifford, V.R, Pearce, F.G, Jameson, G.B, Gerrard, J.A. | | Deposit date: | 2005-07-03 | | Release date: | 2005-10-18 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase.
Biochemistry, 44, 2005
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3I7Q
 | | Dihydrodipicolinate synthase mutant - K161A | | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | | Deposit date: | 2009-07-08 | | Release date: | 2010-04-14 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase?
Biochimie, 92, 2010
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7JZE
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3DU0
 | | E. coli dihydrodipicolinate synthase with first substrate, pyruvate, bound in active site | | Descriptor: | CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL, ... | | Authors: | Dobson, R.C.J, Devenish, S.R.A, Gerrard, J.A, Jameson, G.B. | | Deposit date: | 2008-07-16 | | Release date: | 2008-11-18 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The high-resolution structure of dihydrodipicolinate synthase from Escherichia coli bound to its first substrate, pyruvate.
Acta Crystallogr.,Sect.F, 64, 2008
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1YXD
 | | Structure of E. coli dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine to 2.0 A | | Descriptor: | CHLORIDE ION, LYSINE, POTASSIUM ION, ... | | Authors: | Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A. | | Deposit date: | 2005-02-20 | | Release date: | 2005-08-02 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance.
Acta Crystallogr.,Sect.D, 61, 2005
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2A6L
 | | Dihydrodipicolinate synthase (E. coli)- mutant R138H | | Descriptor: | Dihydrodipicolinate synthase, POTASSIUM ION | | Authors: | Dobson, R.C, Devenish, S.R, Turner, L.A, Clifford, V.R, Pearce, F.G, Jameson, G.B, Gerrard, J.A. | | Deposit date: | 2005-07-03 | | Release date: | 2005-10-18 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase.
Biochemistry, 44, 2005
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7JZC
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5T26
 | | Kinetic, Spectral and Structural Characterization of the Slow Binding Inhibitor Acetopyruvate with Dihydrodipicolinate Synthase from Escherichia coli. | | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase, GLYCEROL, L(+)-TARTARIC ACID, ... | | Authors: | Chooback, L, Thomas, L.M, Karsten, W.E, Fleming, C.D, Seabourn, P. | | Deposit date: | 2016-08-23 | | Release date: | 2016-10-05 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Kinetic, Spectral and Structural Characterization of the Slow Binding Inhibitor Acetopyruvate with Dihydrodipicolinate Synthase from Escherichia coli.
To Be Published
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3I7R
 | | Dihydrodipicolinate synthase - K161R | | Descriptor: | CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL, ... | | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | | Deposit date: | 2009-07-08 | | Release date: | 2010-04-14 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase?
Biochimie, 92, 2010
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3DEN
 | | Structure of E. coli DHDPS mutant Y107W | | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | | Authors: | Pearce, F.G, Gerrard, J.A, Perugini, M.A, Jameson, G.B. | | Deposit date: | 2008-06-10 | | Release date: | 2008-11-25 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme
Biochemistry, 47, 2008
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4EOU
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1DHP
 | | DIHYDRODIPICOLINATE SYNTHASE | | Descriptor: | DIHYDRODIPICOLINATE SYNTHASE, POTASSIUM ION | | Authors: | Mirwaldt, C, Korndoerfer, I, Huber, R. | | Deposit date: | 1995-02-09 | | Release date: | 1997-02-12 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The crystal structure of dihydrodipicolinate synthase from Escherichia coli at 2.5 A resolution.
J.Mol.Biol., 246, 1995
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1S5T
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