6FCH
 
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6FD4
 | | Crystal Structure of Human APRT-Tyr105Phe variant in complex with Adenine, PRPP and Mg2+, 14 hours post crystallization | | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Adenine phosphoribosyltransferase, MAGNESIUM ION | | Authors: | Nioche, P, Huyet, J, Ozeir, M. | | Deposit date: | 2017-12-21 | | Release date: | 2018-08-15 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase.
Cell Chem Biol, 25, 2018
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6FCL
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6HGR
 | | Crystal Structure of Human APRT wild type in complex with IMP | | Descriptor: | Adenine phosphoribosyltransferase, INOSINIC ACID | | Authors: | Nioche, P, Huyet, J, Ozeir, M. | | Deposit date: | 2018-08-23 | | Release date: | 2019-07-31 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | Structural basis for substrate selectivity and nucleophilic substitution mechanisms in human adenine phosphoribosyltransferase catalyzed reaction.
J.Biol.Chem., 294, 2019
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6HGS
 | | Crystal Structure of Human APRT wild type in complex with GMP | | Descriptor: | Adenine phosphoribosyltransferase, GUANOSINE-5'-MONOPHOSPHATE | | Authors: | Nioche, P, Huyet, J, Ozeir, M. | | Deposit date: | 2018-08-23 | | Release date: | 2019-07-31 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural basis for substrate selectivity and nucleophilic substitution mechanisms in human adenine phosphoribosyltransferase catalyzed reaction.
J.Biol.Chem., 294, 2019
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6FD5
 | | Crystal Structure of Human APRT-Tyr105Phe variant in complex with Adenine, PRPP and Mg2+, 14 days post crystallization (with AMP and PPi products partially generated) | | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase, ... | | Authors: | Nioche, P, Huyet, J, Ozeir, M. | | Deposit date: | 2017-12-21 | | Release date: | 2018-08-15 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase.
Cell Chem Biol, 25, 2018
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6HGP
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4X45
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1ZN8
 | | Human Adenine Phosphoribosyltransferase Complexed with AMP, in Space Group P1 at 1.76 A Resolution | | Descriptor: | ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase, CHLORIDE ION | | Authors: | Iulek, J, Silva, M, Tomich, C.H.T.P, Thiemann, O.H. | | Deposit date: | 2005-05-11 | | Release date: | 2006-04-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Structural Complexes of Human Adenine Phosphoribosyltransferase Reveal Novel Features of the APRT Catalytic Mechanism
J.Biomol.Struct.Dyn., 25, 2008
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6FD6
 | | Crystal Structure of Human APRT-Tyr105Phe variant in complex with Adenine, PRPP and Mg2+, 30 days post crystallization (with AMP and PPi products fully generated) | | Descriptor: | ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase, MAGNESIUM ION, ... | | Authors: | Nioche, P, Huyet, J, Ozeir, M. | | Deposit date: | 2017-12-21 | | Release date: | 2018-08-15 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase.
Cell Chem Biol, 25, 2018
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1ZN7
 | | Human Adenine Phosphoribosyltransferase Complexed with PRPP, ADE and R5P | | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 5-O-phosphono-alpha-D-ribofuranose, ADENINE, ... | | Authors: | Iulek, J, Silva, M, Tomich, C.H.T.P, Thiemann, O.H. | | Deposit date: | 2005-05-11 | | Release date: | 2006-04-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Structural Complexes of Human Adenine Phosphoribosyltransferase Reveal Novel Features of the APRT Catalytic Mechanism
J.Biomol.Struct.Dyn., 25, 2008
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6HGQ
 | | Crystal Structure of Human APRT wild type in complex with Hypoxanthine, PRPP and Mg2+ | | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Adenine phosphoribosyltransferase, GLYCEROL, ... | | Authors: | Nioche, P, Huyet, J, Ozeir, M. | | Deposit date: | 2018-08-23 | | Release date: | 2019-07-31 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for substrate selectivity and nucleophilic substitution mechanisms in human adenine phosphoribosyltransferase catalyzed reaction.
J.Biol.Chem., 294, 2019
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6FCI
 | | Crystal Structure of Human APRT wild type in complex with Adenine, PRPP and Mg2+ | | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ADENINE, Adenine phosphoribosyltransferase, ... | | Authors: | Nioche, P, Huyet, J, Ozeir, M. | | Deposit date: | 2017-12-20 | | Release date: | 2018-08-15 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase.
Cell Chem Biol, 25, 2018
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1ZN9
 | | Human Adenine Phosphoribosyltransferase in Apo and AMP Complexed Forms | | Descriptor: | ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase | | Authors: | Iulek, J, Silva, M, Tomich, C.H.T.P, Thiemann, O.H. | | Deposit date: | 2005-05-11 | | Release date: | 2006-04-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural Complexes of Human Adenine Phosphoribosyltransferase Reveal Novel Features of the APRT Catalytic Mechanism
J.Biomol.Struct.Dyn., 25, 2008
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4X44
 | | Crystal Structure of Mutant R89Q of human Adenine phosphoribosyltransferase | | Descriptor: | ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase, GLYCEROL, ... | | Authors: | Pimenta, A, Pereira, H.M, Mercaldi, G, Thiemann, O.H. | | Deposit date: | 2014-12-02 | | Release date: | 2015-12-02 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.0535 Å) | | Cite: | Crystal Structure of Mutant R89Q of human Adenine phosphoribosyltransferase
To Be Published
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1ORE
 | | Human Adenine Phosphoribosyltransferase | | Descriptor: | ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase, CHLORIDE ION | | Authors: | Thiemann, O.H, Silva, M, Oliva, G, Silva, C.H.T.P, Iulek, J. | | Deposit date: | 2003-03-12 | | Release date: | 2004-03-30 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Three-dimensional structure of human adenine phosphoribosyltransferase and its relation to DHA-urolithiasis.
Biochemistry, 43, 2004
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