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PDB: 19 results

3BQP
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BU of 3bqp by Molmil
Crystal Structure of Human Saposin D (orthorhombic)
Descriptor: MAGNESIUM ION, Proactivator polypeptide
Authors:Prive, G.G, Popovic, K.
Deposit date:2007-12-20
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structures of the human ceramide activator protein saposin D.
Acta Crystallogr.,Sect.D, 64, 2008
4UEX
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BU of 4uex by Molmil
Structure of human Saposin A at lysosomal pH
Descriptor: PROSAPOSIN
Authors:Hill, C.H, Read, R.J, Deane, J.E.
Deposit date:2014-12-20
Release date:2015-07-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Human Saposin a at Lysosomal Ph.
Acta Crystallogr.,Sect.D, 71, 2015
4DDJ
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BU of 4ddj by Molmil
Crystal structure of saposin A in complex with lauryldimethylamine-N-oxide (LDAO)
Descriptor: LAURYL DIMETHYLAMINE-N-OXIDE, Saposin-A
Authors:Popovic, K, Prive, G.G.
Deposit date:2012-01-18
Release date:2012-02-15
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of saposin A lipoprotein discs.
Proc.Natl.Acad.Sci.USA, 109, 2012
3BQQ
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BU of 3bqq by Molmil
Crystal Structure of Human Saposin D (triclinic)
Descriptor: PROACTIVATOR POLYPEPTIDE
Authors:Prive, G.G, Popovic, K.
Deposit date:2007-12-20
Release date:2008-02-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the human ceramide activator protein saposin D.
Acta Crystallogr.,Sect.D, 64, 2008
2DOB
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BU of 2dob by Molmil
Crystal Structure of Human Saposin A
Descriptor: CALCIUM ION, Proactivator polypeptide
Authors:Prive, G.G, Ahn, V.E.
Deposit date:2006-04-28
Release date:2006-07-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of saposins A and C.
Protein Sci., 15, 2006
2RB3
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BU of 2rb3 by Molmil
Crystal Structure of Human Saposin D
Descriptor: GLYCEROL, Proactivator polypeptide, SULFATE ION
Authors:Maier, T, Rossman, M, Saenger, W.
Deposit date:2007-09-18
Release date:2008-04-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
4V2O
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BU of 4v2o by Molmil
Structure of saposin B in complex with chloroquine
Descriptor: N4-(7-CHLORO-QUINOLIN-4-YL)-N1,N1-DIETHYL-PENTANE-1,4-DIAMINE, SAPOSIN-B
Authors:Zubieta, C, Lai, X, Doyle, R.P.
Deposit date:2014-10-13
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:The Lysosomal Protein Saposin B Binds Chloroquine.
Chemmedchem, 11, 2016
1N69
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BU of 1n69 by Molmil
Crystal structure of human saposin B
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, SAPOSIN B
Authors:Ahn, V.E, Faull, K.F, Whitelegge, J.P, Fluharty, A.L, Prive, G.G.
Deposit date:2002-11-08
Release date:2003-01-07
Last modified:2021-06-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of saposin B reveals a dimeric shell for lipid binding
Proc.Natl.Acad.Sci.USA, 100, 2003
6SLR
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BU of 6slr by Molmil
Structure of saposin B in complex with atovaquone
Descriptor: 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione, GLYCEROL, Prosaposin
Authors:Zubieta, C, Milliken, B, Doyle, R.
Deposit date:2019-08-20
Release date:2020-09-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structure of saposin B in complex with atovaquone
To Be Published
2GTG
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BU of 2gtg by Molmil
Crystal Structure of Human Saposin C
Descriptor: Proactivator polypeptide
Authors:Prive, G.G, Ahn, V.E.
Deposit date:2006-04-28
Release date:2006-07-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of saposins A and C.
Protein Sci., 15, 2006
2QYP
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BU of 2qyp by Molmil
Orthorhombic Crystal Structure of Human Saposin C Dimer in Open Conformation
Descriptor: Proactivator polypeptide
Authors:Rossmann, M, Saenger, W, Maier, T.
Deposit date:2007-08-15
Release date:2008-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2R1Q
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BU of 2r1q by Molmil
Crystal Structure of Iodinated Human Saposin D in Space Group C2221
Descriptor: Proactivator polypeptide
Authors:Maier, T, Rossman, M, Saenger, W.
Deposit date:2007-08-23
Release date:2008-04-29
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2Z9A
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BU of 2z9a by Molmil
Crystal Structure of Human Saposin C Dimer in Open Conformation
Descriptor: GLYCEROL, Proactivator polypeptide
Authors:Rossmann, M, Saenger, W, Maier, T.
Deposit date:2007-09-18
Release date:2008-04-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2R0R
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BU of 2r0r by Molmil
Crystal Structure of Human Saposin D variant SapD K9E
Descriptor: Proactivator polypeptide, SULFATE ION
Authors:Rossmann, M, Saenger, W, Maier, T.
Deposit date:2007-08-21
Release date:2008-04-29
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
9AXG
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BU of 9axg by Molmil
Human saposin B in the presence of globotriaosylceramide-NBD
Descriptor: MALONATE ION, Saposin-B
Authors:Sawyer, T.K, Garman, S.C.
Deposit date:2024-03-06
Release date:2024-03-13
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Human Saposin B Ligand Binding and Presentation to alpha-Galactosidase A.
Biorxiv, 2024
8EQU
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BU of 8equ by Molmil
Structure of SARS-CoV-2 Orf3a in late endosome/lysosome-like environment, Saposin A nanodisc
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ORF3a protein, Saposin A, ...
Authors:Miller, A.N, Houlihan, P.R, Matamala, E, Cabezas-Bratesco, D, Lee, G.Y, Cristofori-Armstrong, B, Dilan, T.L, Sanchez-Martinez, S, Matthies, D, Yan, R, Yu, Z, Ren, D, Brauchi, S.E, Clapham, D.E.
Deposit date:2022-10-09
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins.
Elife, 12, 2023
9AVS
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BU of 9avs by Molmil
Human alpha-galactosidase A in complex with saposin B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ...
Authors:Sawyer, T.K, Garman, S.C.
Deposit date:2024-03-04
Release date:2024-04-17
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (3.53 Å)
Cite:Human Saposin B Ligand Binding and Presentation to alpha-Galactosidase A.
Biorxiv, 2024
1SN6
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BU of 1sn6 by Molmil
NMR solution structure of human Saposin C in SDS micelles
Descriptor: Proactivator polypeptide
Authors:Hawkins, C.A, de Alba, E, Tjandra, N.
Deposit date:2004-03-10
Release date:2005-03-01
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of human saposin C in a detergent environment.
J.Mol.Biol., 346, 2005
1M12
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BU of 1m12 by Molmil
NMR solution structure of human Saposin C
Descriptor: SAPOSIN C
Authors:de Alba, E, Weiler, S, Tjandra, N.
Deposit date:2002-06-17
Release date:2003-07-29
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of human saposin C: pH-dependent interaction with phospholipid vesicles.
Biochemistry, 42, 2003

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PDB entries from 2024-06-12

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