7KAA
| NMR solution structures of tirasemtiv drug bound to a fast skeletal troponin C-troponin I complex | Descriptor: | 6-ethynyl-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2-ol, CALCIUM ION, Troponin C, ... | Authors: | Mercier, P, Li, M.X, Hartman, J.J, Sykes, B.D. | Deposit date: | 2020-09-30 | Release date: | 2021-03-24 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Basis of Tirasemtiv Activation of Fast Skeletal Muscle. J.Med.Chem., 64, 2021
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2MKP
| N domain of cardiac troponin C bound to the switch fragment of fast skeletal troponin I at pH 6 | Descriptor: | CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ... | Authors: | Robertson, I.M, Pineda-Sanabria, S.E, Holmes, P.C, Sykes, B.D. | Deposit date: | 2014-02-11 | Release date: | 2014-02-26 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Conformation of the critical pH sensitive region of troponin depends upon a single residue in troponin I. Arch.Biochem.Biophys., 552-553, 2014
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