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PDB: 2 results

7KAA
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BU of 7kaa by Molmil
NMR solution structures of tirasemtiv drug bound to a fast skeletal troponin C-troponin I complex
Descriptor: 6-ethynyl-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2-ol, CALCIUM ION, Troponin C, ...
Authors:Mercier, P, Li, M.X, Hartman, J.J, Sykes, B.D.
Deposit date:2020-09-30
Release date:2021-03-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Basis of Tirasemtiv Activation of Fast Skeletal Muscle.
J.Med.Chem., 64, 2021
2MKP
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BU of 2mkp by Molmil
N domain of cardiac troponin C bound to the switch fragment of fast skeletal troponin I at pH 6
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Robertson, I.M, Pineda-Sanabria, S.E, Holmes, P.C, Sykes, B.D.
Deposit date:2014-02-11
Release date:2014-02-26
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Conformation of the critical pH sensitive region of troponin depends upon a single residue in troponin I.
Arch.Biochem.Biophys., 552-553, 2014

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